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61.
OBJECTIVE: To update the 1984 recommendations of the Canadian Task Force on the Periodic Health Examination on the routine screening of asymptomatic patients for infection with Chlamydia trachomatis. OPTIONS: Screening, with the use of culture or nonculture tests, of the general population, of certain high-risk groups or of all pregnant women; or no routine screening. OUTCOMES: Rates of asymptomatic and symptomatic chlamydial infection, perinatal complications, longterm complications of infection (i.e., pelvic inflammatory disease, infertility and ectopic pregnancy), coinfection with other sexually transmitted diseases, disease spread, hospital care, complications of therapy and costs of infection and of screening. EVIDENCE: Search of MEDLINE for articles published between Jan. 1, 1983, and Dec. 31, 1995, with the use of the major MeSH heading "chlamydial infections," references from recent review articles and recommendation by other organizations. VALUES: The evidence-based methods of the Canadian Task Force on the Periodic Health Examination were used. Advice from reviewers and experts and recommendations of other organizations were taken into consideration. Prevention of symptomatic disease and decreased overall costs were given high values. BENEFITS, HARMS AND COSTS: The greatest potential benefits of screening asymptomatic patients for chlamydial infections are the prevention of complications, especially infertility and perinatal complications, and the prevention of disease spread. There is no evidence that screening of the general population for chlamydial infections leads to a reduction in complications, and screening may increase costs. However, there is evidence that annual screening of selected high-risk groups and of pregnant women during the first trimester is beneficial in preventing symptoms and reducing the overall cost resulting from infection. RECOMMENDATIONS: There is fair evidence to support screening and treatment of pregnant women during the first trimester (grade B recommendation) as well as annual screening and treatment of high-risk groups (sexually active women less than 25 years of age, men or women with new or multiple sexual partners during the preceding year, women who use nonbarrier contraceptive methods and women who have symptoms of chlamydial infection: cervical friability, mucopurulent cervical discharge or intermenstrual bleeding; grade B recommendation). There is fair evidence to exclude routine screening of the general population (grade D recommendation). VALIDATION: These recommendations are similar to those of the US Preventive Services Task Force and the US Centers for Disease Control and Prevention, Atlanta. SPONSOR: These guidelines were developed and endorsed by the Canadian Task Force on the Periodic Health Examination, which is funded by Health Canada and the National Health Canada and the National Health Research and Development Program. The principal author (H.D.D.) was supported in part by the Ontario Ministry of Health and the Canadian Infectious Diseases Society Lilly Fellowship. 相似文献
62.
Yaroslav Tenzer Brian L. Davies Ferdinando Rodriguez y Baena 《Robotics and Autonomous Systems》2010,58(3):249-255
This paper outlines work on a novel programmable braking system, which is widely applicable to most passive haptic applications and benefits from a simple design, theoretically infinite positional resolution and the ability to generate stiff collision forces, without the need for any explicit force measurements. Results are also given of a preliminary concept demonstrator which is based on a simple 2-Degrees-Of-Freedom (DOF) Revolute–Revolute (RR) manipulator incorporating the programmable brakes. Performance measures for the joint, as well as figures describing the ability of the 2-DOF prototype to constrain the end effector motion to a plane and a circle, are also provided. 相似文献
63.
Cybercrime and cybercriminal activities continue to impact communities as the steady growth of electronic information systems enables more online business. The collective views of sixty-six computer users and organizations, that have an exposure to cybercrime, were analyzed using concept analysis and mapping techniques in order to identify the major issues and areas of concern, and provide useful advice. The findings of the study show that a range of computing stakeholders have genuine concerns about the frequency of information security breaches and malware incursions (including the emergence of dangerous security and detection avoiding malware), the need for e-security awareness and education, the roles played by law and law enforcement, and the installation of current security software and systems. While not necessarily criminal in nature, some stakeholders also expressed deep concerns over the use of computers for cyberbullying, particularly where younger and school aged users are involved. The government’s future directions and recommendations for the technical and administrative management of cybercriminal activity were generally observed to be consistent with stakeholder concerns, with some users also taking practical steps to reduce cybercrime risks. 相似文献
64.
65.
Abstract. Information technology (IT) innovation research examines the organizational and technological factors that determine IT adoption and diffusion, including firm size and scope, technological competency and expected benefits. We extend the literature by focusing on information requirements as a driver of IT innovation adoption and diffusion. Our framework of IT innovation diffusion incorporates three industry-level sources of information requirements: process complexity, clock speed and supply chain complexity. We apply the framework to US manufacturing industries using aggregate data of internet-based innovations and qualitative analysis of two industries: wood products and beverage manufacturing. Results show systematic patterns supporting the basic thesis of the information processing paradigm: higher IT innovation diffusion in industries with higher information processing requirements; the salience of downstream industry structure in the adoption of interorganizational systems; and the role of the location of information intensity in the supply chain in determining IT adoption and diffusion. Our study provides a new explanation for why certain industries were early and deep adopters of internet-based innovations while others were not: variation in information processing requirements. 相似文献
66.
Matt Jones Steve Jones Gareth Bradley Nigel Warren David Bainbridge Geoff Holmes 《Personal and Ubiquitous Computing》2008,12(7):513-525
Listening to music on personal, digital devices whilst mobile is an enjoyable, everyday activity. We explore a scheme for
exploiting this practice to immerse listeners in navigation cues. Our prototype, ONTRACK, continuously adapts audio, modifying
the spatial balance and volume to lead listeners to their target destination. First we report on an initial lab-based evaluation
that demonstrated the approach’s efficacy: users were able to complete tasks within a reasonable time and their subjective
feedback was positive. Encouraged by these results we constructed a handheld prototype. Here, we discuss this implementation
and the results of field-trials. These indicate that even with a low-fidelity realisation of the concept, users can quite
effectively navigate complicated routes.
相似文献
Matt Jones (Corresponding author)Email: |
Steve JonesEmail: |
Gareth BradleyEmail: |
Nigel WarrenEmail: |
David BainbridgeEmail: |
Geoff HolmesEmail: |
67.
Nigel Burton 《程序员》2008,(5):12-13
27年前当我还是个学生的时候,我每周六都会去一家英格兰的首批电脑卖场打工。起初我觉得工作的每一天都很漫长,也几乎没有什么工资,但在那里我很享受于能使用到早期的第一代微型计算机,很快让自己变得非常充实起来。我还记得那时电脑卖场办了一个英文叫做“Easy Sell”的活动, 相似文献
68.
Armstrong MR Boyden K Browning ND Campbell GH Colvin JD DeHope WJ Frank AM Gibson DJ Hartemann F Kim JS King WE LaGrange TB Pyke BJ Reed BW Shuttlesworth RM Stuart BC Torralva BR 《Ultramicroscopy》2007,107(4-5):356-367
Although recent years have seen significant advances in the spatial resolution possible in the transmission electron microscope (TEM), the temporal resolution of most microscopes is limited to video rate at best. This lack of temporal resolution means that our understanding of dynamic processes in materials is extremely limited. High temporal resolution in the TEM can be achieved, however, by replacing the normal thermionic or field emission source with a photoemission source. In this case the temporal resolution is limited only by the ability to create a short pulse of photoexcited electrons in the source, and this can be as short as a few femtoseconds. The operation of the photo-emission source and the control of the subsequent pulse of electrons (containing as many as 5 x 10(7) electrons) create significant challenges for a standard microscope column that is designed to operate with a single electron in the column at any one time. In this paper, the generation and control of electron pulses in the TEM to obtain a temporal resolution <10(-6)s will be described and the effect of the pulse duration and current density on the spatial resolution of the instrument will be examined. The potential of these levels of temporal and spatial resolution for the study of dynamic materials processes will also be discussed. 相似文献
69.
Valence electron energy-loss spectroscopy (VEELS) performed in a monochromated scanning transmission electron microscope was used to measure the energy gaps of individual quantum dots (QDs). The gap energies of a series of CdSe QDs measured by VEELS reveal the expected quantum confinement effect; the gap energy increases with decreasing particle size. However, the values derived from these first VEELS measurements of single QDs are larger than the values commonly measured by optical spectroscopy. As standard optical methods lack the spatial resolution to probe individual nanoparticles, the particle-size distribution influences the optical response. It is suggested that the impact of the particle-size distribution accounts for the discrepancy between the energy-gap values derived from VEELS of single QDs and from optical methods of ensembles of QDs. 相似文献
70.
Davies BL Rodriguez y Baena FM Barrett AR Gomes MP Harris SJ Jakopec M Cobb JP 《Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine》2007,221(1):71-80
A brief history of robotic systems in knee arthroplasty is provided. The place of autonomous robots is then discussed and compared to more recent 'hands-on' robotic systems that can be more cost effective. The case is made for robotic systems to have a clear justification, with improved benefits compared to those from cheaper navigation systems. A number of more recent, smaller, robot systems for knee arthroplasty are also described. A specific example is given of an active constraint medical robot, the ACROBOT system, used in a prospective randomized controlled trial of unicondylar robotic knee arthroplasty in which the robot was compared to conventional surgery. The results of the trial are presented together with a discussion of the need for measures of accuracy to be introduced so that the efficacy of the robotic surgery can be immediately identified, rather than have to wait for a number of years before long-term clinical improvements can be demonstrated. 相似文献