Use of prosthesis-generated computed tomographic information for diagnostic and surgical treatment planning

Diagnosis, treatment planning, and prediction of a final implant-supported prosthetic outcome require precise noninvasive presurgical information. By combining the use of a clinically verified barium-coated template and interactive computed tomography (SIM/Plant, Columbia Scientific, Inc., Columbia, Maryland), the implant team can determine and address the relevant issues affecting treatment outcomes. Those issues include: implant-prosthesis incompatibility, recognition of anatomic limitations and anomalies, the need for presurgical bone augmentation, implant diameter and distribution, abutment type and angle, bone density, soft tissue augmentation requirements, accurate fee determination, and medicolegal protection. The data collection methodology and format for the Mecall and Rosenfeld prosthesis prediction analysis are discussed as part of case presentation.     

Gender gap in cystic fibrosis mortality

The authors conducted the largest study to date of survival in cystic fibrosis. The study cohort consisted of all patients with cystic fibrosis seen at Cystic Fibrosis Foundation-accredited care centers in the United States between 1988 and 1992 (n = 21,047), or approximately 85% of all US patients diagnosed with cystic fibrosis. Cox proportional hazards regression analysis was used to compare the age-specific mortality rates of males and females and to identify risk factors serving as potential explanatory variables for the gender-related difference in survival. Among the subjects 1-20 years of age, females were 60% more likely to die than males (relative risk = 1.6, 95% confidence interval 1.4-1.8). Outside this age range, male and female survival rates were not significantly different. The median survival for females was 25.3 years and for males was 28.4 years. Nutritional status, pulmonary function, and airway microbiology at a given age were strong predictors of mortality at subsequent ages. Nonetheless, differences between the genders in these parameters, as well as pancreatic insufficiency, age at diagnosis, mode of presentation, and race, could not account for the poorer survival among females. Even after adjustment for all these potential risk factors, females in the age range 1-20 years remained at greater risk for death (relative risk = 1.6, 95% confidence interval 1.2-2.1). The authors concluded that in 1- to 20-year-old individuals with cystic fibrosis, survival in females was poorer than in males. This "gender gap" was not explained by a wide variety of potential risk factors.     

Shooting a smooth video with a shaky camera

Abstract. The image sequence in a video taken by a moving camera may suffer from irregular perturbations because of irregularities in the motion of the person or vehicle carrying the camera. We show how to use information in the image sequence to correct the effects of these irregularities so that the sequence is smoothed, i.e., is approximately the same as the sequence that would have been obtained if the motion of the camera had been smooth. Our method is based on the fact that the irregular motion is almost entirely rotational, and that the rotational image motion can be detected and corrected if a distant object, such as the horizon, is visible. Received: 14 February 2001 / Accepted: 11 February 2002 Correspondence to: A. Rosenfeld     

3-D shape recovery using distributed aspect matching

An approach to the recovery of 3-D volumetric primitives from a single 2-D image is presented. The approach first takes a set of 3-D volumetric modeling primitives and generates a hierarchical aspect representation based on the projected surfaces of the primitives; conditional probabilities capture the ambiguity of mappings between levels of the hierarchy. From a region segmentation of the input image, the authors present a formulation of the recovery problem based on the grouping of the regions into aspects. No domain-independent heuristics are used; only the probabilities inherent in the aspect hierarchy are exploited. Once the aspects are recovered, the aspect hierarchy is used to infer a set of volumetric primitives and their connectivity. As a front end to an object recognition system, the approach provides the indexing power of complex 3-D object-centered primitives while exploiting the convenience of 2-D viewer-centered aspect matching; aspects are used to represent a finite vocabulary of 3-D parts from which objects can be constructed     

Estimation of exposure to sunlight of the liner under a tiled roof

One construction for a pitched roof is to use tiles on battens, with a liner attached below the battens. The shape of some types of tiles is such that, at each corner where four tiles overlap, a small gap is formed. At certain positions of the sun solar radiation can penetrate through these gaps and strike the liner, accelerating its degradation. The purpose of this study is to estimate the extent and duration of the exposure. A typical gap is modelled in a ray-tracing program and the size and position of the illuminated area on the liner is calculated for given directions of the light beam relative to the roof. Analytic expressions for the size of the illuminated area are obtained using a thick slit model. The accuracy of the model was assessed by some experimental measurements. The exposure over one year of the roof liner was calculated using the Design Reference Year for Copenhagen, Denmark. Simulations were carried out for a roof tilted at 25°, 35° or 45°, facing SE, S, SW or W. For the particular roof construction and gap studied, the maximum annual exposure of a 25 mm² piece of the liner placed 150 mm below the gap (corresponding to about 100 mm below the base of the tiles) is about 140 kJ m⁻² to UV-B and 4.2 MJ m⁻² to UV-A radiation. Variations in tile size and misalignment of tiles could lead to other gap shapes and sizes, possibly leading to greater exposure. Constructions with the liner placed closer to the tiles would also lead to greater exposures. However the method developed in this study could form the basis of a standard method of assessment.     

Approximation of waveforms and contours by one-dimensional pyramid linking

A method of segmenting an image was recently developed based on constructing links between the pixels at consecutive levels in a “pyramid” of successively reduced-resolution versions of the image. We develop here an analgous method of piecewise approximating a waveform or a closed curve by linking nodes in a one-dimensional “pyramid” of reduced-resolution versions of the curve. The method can be efficiently implemented in parallel on a one-dimensional cellular array or cellular “pyramid”.     

Image processing on MPP: 1

The Massively Parallel Processor (MPP) is a 128 by 128 array of processing elements that communicate with their horizontal and vertical neighbors by shifting data one bit at a time. This paper describes the efficient use of MPP for various types of image processing operations, including point and local operations, discrete transforms and computation of image statistics. A comparison between MPP and ZMOB (a system consisting of 256 microprocessors) is also presented.     

Comparison of mRNA binding by Met-tRNAf binding protein and mRNA-associated proteins

One of the heterogeneous mRNA binding activities in the 0.5 M KCl eluate of rabbit reticulocyte polyribosomes co-purified to apparent homogeneity through phosphocellulose and DEAE-cellulose chromatography and isoelectric focusing with the GTP-dependent Met-tRNAf binding protein. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis following iodination revealed putative subunits of 51,000 and 39,000 apparent molecular weights. Specificity of mRNA binding by this protein was suggested since the ability of poly(A)-rich mRNA to compete for binding of [3H]poly(A)-rich mRNA exceeded by 10- to 100-fold that of most natural or synthetic RNAs tested, except for the hybrid poly(G) - poly(C) which was almost as effective, and poly(G), which was more effective, at competing for protein-dependent binding. The mRNA binding activity exhibited complete GTP independence and no apparent divalent cation requirement. GDP inhibited Met-tRNAf binding but neither GDP, GMP, nor 7-methylguanosine 5'-monophosphate inhibited mRNA binding by this protein. Similar data were obtained with respect to the ability of natural or synthetic RNAs to compete for binding of [3H]poly(A)-rich mRNA by proteins associated with purified rabbit reticulocyte polyribosomal mRNA-protein particles; while poly(A) was an ineffective competitor, poly(G) was more effective than even mRNA at competing for protein-dependent binding. No significant binding of Met-tRNAf by mRNA-protein particles was detected. Polyacrylamide gel electrophoresis following reduction of mRNA-protein particles revealed apparent co-migration of a major protein with one subunit of the GTP-dependent Met-tRNAf binding protein, but no protein comparable to the 39,000 dalton subunit protein.