A DC-coupled wide dynamic range AGC amplifier IC for 560-Mbit/s optical transmission

A wide-band high-gain AGC amplifier stabilizing the output dc level against a broad gain variation is proposed and monolithically integrated using high-speed 1-μm Si-bipolar IC technology. The fabricated IC exhibits a maximum gain of 39 dB, gain dynamic range of 44 dB, bandwidth of 800 MHz, and output dc-level fluctuation of 8 mV, and realizes wide dynamic range and direct dc-coupling of the multistage AGC amplifier. Also, in order to examine the feasibility of the fabricated IC, a 1.5-μm-wavelength optical transmission experiment was carried out using DFB-LD and InGaAs-APD. Measured minimum received optical power for an error rate of 10^-9is -40 dBm at 560 Mbit/s and -38 dBm at 1.12 Gbit/s. Optical dynamic range of 30 dB is also achieved by using the fabricated IC and APD.     

Cooking up an interactive olfactory game display.

It's long been possible to give users outside an actual environment that environment's visual and auditory information and thus contribute to establishing presence. However, we've yet to establish much presence when users require olfactory information - such as in environments focused on foods, flowers, perfumes, or, in some cases, more offensive smells. Recently, several VR researchers have become interested in olfaction and olfactory displays that present smells in virtual environments (VEs). In this article, we describe our interactive olfactory display. One of our development goals is to confirm the assumption that users' interactions with the system increases presence. Thus, we used our interactive olfactory display to develop a cooking game in collaboration with electronic engineers and artists.     

Agglomeration of magnesium oxide particles formed by the decomposition of magnesium hydroxide

The agglomeration process of MgO powder derived from Mg (OH)₂ was investigated at fixed temperatures of 600, 800, 900 and 1200° C; these temperatures were chosen as representative of four regions, i.e. below 600° C, 650 to 850° C, 850 to 1050°C and 1050 to 1200° C previously reported. At 600° C, coherent crystallites coalesced within the heating time of 60 min; on further heating till 300 min, the primary particles which consisted of crystallites grew rapidly. The original Mg (OH)₂ framework or pseudomorphs, composed of minute crystallites and primary particles, still remained in the powder. At 800° C, the pseudomorphs had disintegrated into fragments. The crystallite growth and primary particle growth were accelerated with increasing the heating times beyond 60 min. At 900° C, a further fragmentation of agglomerates occurred with increasing the heating times; the crystallite and primary particle growth in fragments brought about the pore coalescence. At 1200° C, the crystallite and primary particle growth proceeded with the coarsening of pores; on heating beyond 240 min, the crystallites and primary particles grew rapidly due to the entrapment of pores within them.     

Sinterability of various high-purity magnesium oxide powders

The sinterability of high-purity MgO powders with different production histories was investigated to make clear the relationship between the powder characterization, the densification processes, and the changes in microstructure both with increasing temperature at a rate of 10° C min^–1 and at a fixed temperature of 1450° C for 5 h. The densification behaviour and the changes in microstructure of these compressed bodies were affected chiefly by their original surface activity and degree of agglomeration, depending on the production histories: (i) the ultra-fine and well-dispersed powder prepared by the vapour-phase oxidation process showed that densification proceeded with an appreciable grain growth with few closed pores remaining; (ii) powder derived from the sea-water magnesia process showed that the densification behaviour was affected by the species of magnesium salt, i.e. basic magnesium carbonate or magnesium hydroxide, used as a precursor; however, whichever magnesium salt was used, its sintered compact showed similar closed porosities and grain-size distributions; (iii) powder derived from the spark-discharge process contained skeletons of the original Mg(OH)₂ particles; however, the densification proceeded gradually with slow grain growth, reflecting the fact that the powder has a moderate surface area (36 m² g^–1). The sintered compact from (iii) had a small closed porosity and the smallest grain-size distribution among the compacts used in this investigation.     

Effect of voluntary exercise on maximal oxygen uptake in young female Fischer 344 rats

The effect of voluntary exercise on maximal oxygen uptake (VO2 max) was studied in young female Fischer 344 rats. After 10 weeks of wheel-running training, the absolute VO2 max and VO2 max relative to body mass increased without a decline in body mass. The running speed eliciting VO2 max, heart and soleus muscle mass, and succinate dehydrogenase (SDH) activity in the soleus muscle also increased. These results suggest that voluntary exercise is an effective means of increasing the aerobic exercise capacity of young female Fischer 344 rats.     

Development of an indoor navigation system for a monocular-vision-based autonomous mobile robot

We have developed a technology for a robot that uses an indoor navigation system based on visual methods to provide the required autonomy. For robots to run autonomously, it is extremely important that they are able to recognize the surrounding environment and their current location. Because it was not necessary to use plural external world sensors, we built a navigation system in our test environment that reduced the burden of information processing mainly by using sight information from a monocular camera. In addition, we used only natural landmarks such as walls, because we assumed that the environment was a human one. In this article we discuss and explain two modules: a self-position recognition system and an obstacle recognition system. In both systems, the recognition is based on image processing of the sight information provided by the robot’s camera. In addition, in order to provide autonomy for the robot, we use an encoder and information from a two-dimensional space map given beforehand. Here, we explain the navigation system that integrates these two modules. We applied this system to a robot in an indoor environment and evaluated its performance, and in a discussion of our experimental results we consider the resulting problems.     

Cellular Antisense Activity of PNA–Oligo(bicycloguanidinium) Conjugates Forming Self‐Assembled Nanoaggregates

A series of peptide nucleic acid–oligo(bicycloguanidinium) (PNA–BG_n) conjugates were synthesized and characterized in terms of cellular antisense activity by using the pLuc750HeLa cell splice correction assay. PNA–BG₄ conjugates exhibited low micromolar antisense activity, and their cellular activity required the presence of a hydrophobic silyl terminal protecting group on the oligo(BG) ligand and a minimum of four guanidinium units. Surprisingly, a nonlinear dose–response with an activity threshold around 3–4 μM , indicative of large cooperativity, was observed. Supported by light scattering and electron microscopy analyses, we propose that the activity, and thus cellular delivery, of these lipo‐PNA–BG₄ conjugates is dependent on self‐assembled nanoaggregates. Finally, cellular activity was enhanced by the presence of serum. Therefore we conclude that the lipo‐BG‐PNA conjugates exhibit an unexpected mechanism for cell delivery and are of interest for further in vivo studies.     

Analysis of ultrasonic welding process of mild steel and 5052 aluminium alloy

Ultrasonic welding of mild steel sheet (SPCC) and aluminium alloy sheet (A5052) was conducted using two different weld tips of a knurled tip (K-tip) and a curved shape tip without knurled edges (C-tip). Behaviours of the weld tip and the welded materials during the weld process were analysed using a high-speed camera observation and an image correlation. The C-tip welding shows a completely different displacement behaviour from the K-tip welding; a relative motion between the tool tip and A5052 in contact with the tip predominantly occurs in the C-tip in contrast to a relative motion between A5052 and SPCC observed in the K-tip. The joint strength using the C-tip was higher than that using the K-tip under the weld conditions in this study. It is demonstrated that the relative motion behaviour in the C-tip causes a macroscopic deformation of A5052 in the vibration direction. This phenomenon promotes growth of a bonded region, resulting in the increase of joint strength. It is surmised that Fe–Al intermetallic layer forms at the weld interface, and the joint strength consequently decreases for the longer weld time condition.     

Correction: patil, a. Et Al. Hub promiscuity in protein-protein interaction networks. Int. J. Mol. Sci. 2010, 11, 1930-1943

[This corrects the article on p. 1930 in vol. 11, PMID: 20480050.].     

Electron microscopic observation on the parathyroid gland of the cardiomyopathic hamster (UM-X7.1 Syrian hamster).

The ultrastructure of the parathyroid gland (PTG) of the UM-X7.1 cardiomyopathic hamster (the UM-X7.1) was qualitatively and quantitatively compared with that of the normal hamster. In the UM-X7.1, the Golgi apparatus and rER were well developed compared with those of the control hamster. Morphometric analysis revealed that the mean values of the Golgi apparatus, rER and large vacuolar bodies were significantly greater in the UM-X7.1 than in the normal hamster and the mean value of lipid droplets was significantly less in the UM-X7.1 than in the normal hamster. Ultrastructurally, we consider that in the UM-X7.1, the synthesis and release of the parathyroid hormone may be activated by an excessive amount of circulating catecholamine, and the functional activity of the PTG may be higher than that in the normal hamster.