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Biodegradable Microparticles for Simultaneous Detection of Counterfeit and Deteriorated Edible Products 下载免费PDF全文
Ivan Rehor Sophie van Vreeswijk Tina Vermonden Wim E. Hennink Willem K. Kegel Huseyin Burak Eral 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(39)
In an era of globalized trade relations where food and pharmaceutical products cross borders effortlessly, consumers face counterfeit and deteriorated products at elevated rates. This paper presents multifunctional, biodegradable hydrogel microparticles that can provide information on the authenticity and the potential deterioration of the tagged food or pharmaceutical formulations. These microparticles integrate spatially patterned authenticity code with two sensors—the first one detects possible presence of pathogenic microbes through monitoring pH while the second one identifies products stored above optimal temperatures via optical monitoring of the microparticle degradation. Particles are synthesized from a biocompatible polymer and a photoinitiator, dextran modified with 2‐hydroxyethylmethacrylate and riboflavin, respectively, using a continuous, high throughput method stop‐flow lithography. The proposed synthesis approach also enables crosslinking with visible light bringing about additional flexibility to flow lithography. Model liquid and solid food and pharmaceutical products are successfully labeled with microparticles and the functionality of the sensors in aqueous solutions is demonstrated. 相似文献
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In this paper, a social capital perspective is applied to the relationship between the IT department and the Business organization. IT and Business are conceptualized as different occupational communities, with different understandings of their work. Our focus is on the level of social capital and the process of knowledge sharing between these occupational communities. We analyze the role that these factors play in reaching a mutual understanding within the process of IS development, and the influence this has on the perceived performance of the IT organization. Our study, combining qualitative and quantitative methods, points out that a lack of social capital (structural, relational as well as cognitive) can serve as an explanation for the often problematic relationship between these communities. Our analyses also show that social capital is especially relevant for the Business organization's perception of IT performance, whereas the IT department's perception is that performance is primarily dependent on the exchange of information. 相似文献
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The process of designing a networked learning environment can be characterized by a high degree of uncertainty. This is especially true when the design includes innovative technologies. It is difficult to design a networked learning environment that closely fits the requirements of the educational practice. Often the technology seems leading in the design process because it is the most tangible aspect of the e-learning environment. This brings along the risk that the technology becomes detached from its context of use.Design patterns are a means to overcome this problem of detachment between design and practice. Design patterns make the tight relationship between the two more explicit. In this paper we further elaborate on the relationship between design and practice. We will stress the importance of theory in the development of design patterns. Theory development is an essential aspect of our approach to the development of design patterns. The approach is oriented towards a systematic analysis of problems and the development of conceptual models that guide the definition and evaluation of design patterns. In this paper we present a case study of how the approach was used to develop design patterns for networked learning in the classroom. 相似文献
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A connected algebraic group in characteristic 0 is uniquely determined by its Lie algebra. In this paper algorithms are given for constructing an algebraic group in characteristic 0, given its Lie algebra. In particular, this leads to an algorithm for finding a maximal reductive subgroup and the unipotent radical of an algebraic group. 相似文献
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In domains like decision theory and social choice theory it is known for a long time that stochastic transitivity properties yield necessary and sufficient conditions for the ranking or utility representability of reciprocal preference relations. In this article we extend these results for reciprocal preference relations originating from the pairwise comparison of random vectors in a machine learning context. More specifically, the expected ranking accuracy (ERA) is such a reciprocal relation that occurs in multi-class classification problems, when ranking or utility functions are fitted to the data in a pairwise manner. We establish necessary and sufficient conditions for which these pairwise bipartite ranking functions can be simplified to a single ranking function such that the pairwise expected ranking accuracies of both models coincide. Similarly as for more common reciprocal preference relations, cycle transitivity plays a crucial role in this new setting. We first consider the finite sample case, for which expected ranking accuracy can be estimated by means of the area under the ROC curve (AUC), and subsequently, we further generalize these results to the underlying distributions. It turns out that the ranking representability of pairwisely compared random vectors can be expressed elegantly in a distribution-independent way by means of a specific type of cycle transitivity, defined by a conjunctor that is closely related to the algebraic product. 相似文献
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Marcel P. C. M. Krijn Siebe T. de Zwart Dick K. G. de Boer Oscar H. Willemsen Maarten Sluijter 《Journal of the Society for Information Display》2008,16(8):847-855
Abstract— An attractive concept for 3‐D displays is the one based on LCDs equipped with lenticular lenses. This enables autostereoscopic multiview 3‐D displays without a loss in brightness. A general issue in multiview 3‐D displays is their relatively low spatial resolution because the pixels are divided among the different views. To overcome this problem, we have developed switchable displays, using liquid‐crystal (LC) filled switchable lenticulars. In this way, it is possible to have a high‐brightness 3‐D display capable of fully exploiting the native 2‐D resolution of the underlying LCD. The feasibility of LC‐filled switchable lenticulars was shown in several applications. For applications in which it is advantageous to be able to display 3‐D and 2‐D content simultaneously, a 42‐in. locally switchable prototype having a matrix electrode structure was developed. These displays were realized using cylindrically shaped lenticular lenses in contact with LC. An alternative for these are lenticulars based on gradient‐index (GRIN) LC lenses. Preliminary results for such switchable GRIN lenses are presented as well. 相似文献
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