温针传热研究与电子温针的研制

温针临床疗效显著、应用范围广,但其操作有许多不便之处。温针疗效来源于针刺手法和温热刺激,艾炷燃烧产生的温热刺激在治疗中起着重要的作用,因此有必要研究其热量传递过程,并模拟温热刺激,研制电子温针。本文采用有限元方法分析温针稳定工作时组织内的温度场分布,并在此基础上,研制毫针微型加热装置。研究认为由于金属针身的快速导热能力,组织内的热量主要集中在针身和针身附近,从而热量能更加有效地作用于穴位,获得更好的疗效。针身的热传导在组织内传热中发挥着重要的作用。所研制的电子温针依靠针身传导热量到穴位处,使皮肤进针点的温度根据临床治疗要求在37--45℃范围内可调。     

基于多温度信息融合的PCR仪

本系统采用双卡尔曼滤波器算法对多通道的试剂热辐射、环境温度和热源温度数据进行信息融合从而估计出多通道试剂表面温度的真实值,有效克服热成像仪的缺点.算法结合了迭代扩展卡尔曼滤波器(IEKF)非线性估计收敛快与线性卡尔曼滤波器(KF)实时性高的优点,实现了多通道实时滤波与温控.实验表明,滤波估计后的红外热成像仪可使误差由2℃降低到0.3℃;聚合酶链式反应(PCR)测试结果较为满意,恒温时间设置更加合理.     

NBS–rCDs(OH−) chemiluminescence analysis system for the determination of cobalt ions

A novel sensing system has been designed for cobalt ion detection based on a cobalt ion improved chemiluminescence (CL) in N-bromosuccinimide(NBS)-reduced carbon quantum dot (rCD) (OH⁻) system. The mechanism of this CL analysis system has been preliminarily studied. In this work, it was demonstrated that this facile methodology offers rapid, sensitive and reliable detection for cobalt ions with a detection limit as low as 3.252 × 10^− 6 mol/L and a linearity range from 1.004 × 10^− 5 to 1.004 × 10^− 3 mol/L (r = 0.9990), which has promising application prospects.     

基于改进CenterNet的竹条表面缺陷检测方法

在竹条表面缺陷检测中,竹条表面缺陷形状各异,成像环境脏乱,现有基于卷积神经网络(CNN)的目标检测模型面对这样特定的数据时并不能很好地发挥神经网络的优势;而且竹条来源复杂且有其他条件限制,因此没办法采集所有类型的数据,导致竹条表面缺陷数据量少到CNN不能充分学习.针对这些问题,提出一种专门针对竹条表面缺陷的检测网络.该...     

Analysis of sEMG signal for KOA classification

The sEMG signals are collected from the vastus lateralis,vastus medialis,biceps femoris,and semitendinosus of lower extremity during level walking among control subjects and knee osteoarthritis (OA) pa...     

Carbon dots-initiated luminol chemiluminescence in the absence of added oxidant

This paper reports for the first time the chemiluminescence (CL) of luminol in the absence of added oxidant with carbon dots (CDs) as the catalyst. By means of CL spectra, UV–vis spectra, electron spin resonance spectra, Fourier transform infrared and X-ray photoelectron spectra, the possible CL reaction mechanism is proposed. The CL luminophor was still 3-aminophthalate, the CL enhancement of luminol system was supposed to originate from the intrinsic catalytic activity of CDs, which can efficiently catalyze the decomposition of dissolved oxygen to generate superoxide radical anion in luminol solution. Then, the resulting superoxide radical anion reacted with luminol to cause CL emission. Furthermore, the effects of size and surface states on the catalytic activity of CDs were investigated. The results suggested that the catalytic activity of CDs are mainly affected by the surface states, and the size of CDs display little influence on the catalytic activity of CDs. Therefore, the catalytic activity of CDs can be tuned by modulating functional groups on the surface of CDs, which sheds new light on the characteristic of CDs.     

串联双卡尔曼滤波器在PCR非接触测温中的应用

传统PCR仪对试剂样品进行接触式测温时,存在测量迟滞大、无法直接测量试剂温度以及只能测量局部点温度的缺点,采用红外温度传感器对样品进行非接触测量可以克服以上局限.但红外温度传感器测量噪声较大,为此提出一种串联式双卡尔曼滤波算法来对红外温度传感器采集到的温度数据进行实时滤波.滤波过程中迭代卡尔曼滤波器(IEKF)与线性卡...     

基于知识蒸馏的超分辨率卷积神经网络压缩方法

针对目前用于超分辨率图像重建的深度学习网络模型结构深且计算复杂度高，以及存储网络模型所需空间大，进而导致其无法在资源受限的设备上有效运行的问题，提出一种基于知识蒸馏的超分辨率卷积神经网络的压缩方法。该方法使用一个参数多、重建效果好的教师网络和一个参数少、重建效果较差的学生网络。首先训练好教师网络，然后使用知识蒸馏的方法将知识从教师网络转移到学生网络，最后在不改变学生网络的网络结构及参数量的前提下提升学生网络的重建效果。实验使用峰值信噪比（PSNR）评估重建质量的结果，使用知识蒸馏方法的学生网络与不使用知识蒸馏方法的学生网络相比，在放大倍数为3时，在4个公开测试集上的PSNR提升量分别为0.53 dB、0.37 dB、0.24 dB和0.45 dB。在不改变学生网络结构的前提下，所提方法显著地改善了学生网络的超分辨率重建效果。     

Nonlinear model predictive control of functional electrical stimulation

Minimizing the amount of electrical stimulation can potentially mitigate the adverse effects of muscle fatigue during functional electrical stimulation (FES) induced limb movements. A gradient projection-based model predictive controller is presented for optimal control of a knee extension elicited via FES. A control Lyapunov function was used as a terminal cost to ensure stability of the model predictive control. The controller validation results show that the algorithm can be implemented in real-time with a steady-state RMS error of less than 2°. The experiments also show that the controller follows step changes in desired angles and is robust to external disturbances.     

基于红外热成像的PCR温控系统

电化学实时定量PCR仪中,对热循环3个温度区试剂温度的精度控制至关重要,因为其决定了PCR反应效率.根据非稳态传热原理,热量从基座传递到试剂存在延迟,因此基座上的接触式温度传感器无法直接测得试剂的温度.设计基于红外热成像仪温度检测的温控系统.可以同时对多通道试剂表面的温度进行直接测量,从而准确控制DNA解链-结合-延伸时间,提高DNA扩增效率.为了实现红外热像仪对温度的精确测量,对获取的红外温度进行中值滤波,根据热辐射理论与红外热像仪的测温原理以及公式推导,在线得到被测试剂表面发射率,通过换算从而获得试剂真实温度.实验表明,校准后热像仪测温精度由2.0℃提高到0.3℃;对试剂表面温度的监控使得PCR温控更加准确高效,具有重要意义.