基于眼前节相干光断层扫描成像的核性白内障分类算法

白内障是导致视觉损害和致盲的主要眼病,眼前节光学相干断层成像技术(Anterior Segment Optical Coherence Tomography,AS-OCT)具有非接触、高分辨率、检查快速、客观定量化测量等特点,在临床上已经被广泛应用于眼病的诊断.目前缺乏基于眼前节OCT图像的核性白内障分类研究工作,为此...     

AS-OCT图像下的自动皮质性白内障分类框架

白内障是一种主要导致视觉损伤的眼病. 早期干预和白内障手术是改善患者视力和生活质量的主要手段. 眼前节光学相干断层成像图像 (anterior segment optical coherence tomography, AS-OCT) 是一种新型眼科图像, 其具有非接触、高分辨率、检查快速等特点. 在临床上, 眼科医生已经逐渐采用AS-OCT图像进行眼科疾病如青光眼的诊断, 然而尚未有研究工作利用它进行皮质性白内障 (cortical cataract, CC) 自动分类. 为此, 提出了一个基于AS-OCT图像的自动皮质性白内障分类框架, 由图像预处理、特征提取、特征筛选和分类等4部分组成. 首先, 利用反光区域去除和对比度增强方法进行图像预处理; 紧接着使用灰度共生矩阵 (grey level co-occurrence matrix, GLCM)、灰度区域大小矩阵 (grey level size zone matrix, GLSZM) 和邻域灰度差矩阵 (neighborhood grey tone difference matrix, NGTDM) 方法从皮质区域提取了22个特征; 然后, 采用斯皮尔曼相关系数方法对提取的特征进行特征重要性分析并筛除冗余特征; 最后利用线性支持向量机方法进行分类. 在一个临床AS-OCT图像数据集上的实验结果表明, 所提出的皮质性白内障分类框架准确率、召回率、精确率和F1分别达到86.04%, 86.18%, 88.27%和86.35%, 取得与先进的深度学习算法接近的性能, 表明其具有作为辅助眼科医生进行皮质性白内障临床诊断工具的潜力.     

Machine Learning for Cataract Classification/Grading on Ophthalmic Imaging Modalities: A Survey

Cataracts are the leading cause of visual impairment and blindness globally. Over the years, researchers have achieved significant progress in developing state-of-the-art machine learning techniques for automatic cataract classification and grading, aiming to prevent cataracts early and improve clinicians’ diagnosis efficiency. This survey provides a comprehensive survey of recent advances in machine learning techniques for cataract classification/grading based on ophthalmic images. We summarize existing literature from two research directions: conventional machine learning methods and deep learning methods. This survey also provides insights into existing works of both merits and limitations. In addition, we discuss several challenges of automatic cataract classification/grading based on machine learning techniques and present possible solutions to these challenges for future research.