γ—TiAl增压涡轮熔模铸造过程数值模拟研究

根据熔模型壳离心浇注的铸造工艺特点，建立了γ－TiAl增压涡轮凝固传热过程的数值模型，推导了离心压力下γ－TiAl金属间化合物的凝固收缩和补缩过程数学模型，模拟计算了γ－TiAl增压涡轮铸件的温度场和收缩缺陷，结果表明，模型能可靠计算γ－TiAl增压涡轮铸件凝固过程的温度分布和准确预测铸件的收缩缺陷，数值模拟结果与实验结果吻合良好，数值模拟结果证实了前期工作所提出的进一步减少及消除收缩缺陷的优化工艺措施的合理性。     

灰铸铁几个关键技术问题的探讨

对灰铸铁熔炼中的几个关键问题进行探讨：1）锰、硫对灰铸铁力学性能及切削加工性能的影响；2）硬质点颗粒对断屑性能的影响；3）时效处理对高速切削时刀具寿命的影响；4）如何减小高强度灰铸铁的收缩倾向；5）如何生产HT350及更高牌号的灰铸铁。     

IS风险评估方法分类研究*

尝试分别从信息技术演化过程和驱动因素两个方面对信息系统风险评估方法(ISRAM)进行分类.首先选择信息技术和ISRAM发展的时间主线划分ISRAM,然后提取ISRAM设计实现过程中考虑的驱动因素划分ISRAM,并分别给出两种分类方法的半形式化描述;最后,分析目前ISRAM面临的挑战和未来发展趋势.     

A Novel Volume-Stable Collagen Matrix Induces Changes in the Behavior of Primary Human Oral Fibroblasts,Periodontal Ligament,and Endothelial Cells

The aim of the present study was to investigate the influence of a novel volume-stable collagen matrix (vCM) on early wound healing events including cellular migration and adhesion, protein adsorption and release, and the dynamics of the hemostatic system. For this purpose, we utilized transwell migration and crystal violet adhesion assays, ELISAs for quantification of adsorbed and released from the matrix growth factors, and qRT-PCR for quantification of gene expression in cells grown on the matrix. Our results demonstrated that primary human oral fibroblasts, periodontal ligament, and endothelial cells exhibited increased migration toward vCM compared to control cells that migrated in the absence of the matrix. Cellular adhesive properties on vCM were significantly increased compared to controls. Growth factors TGF-β1, PDGF-BB, FGF-2, and GDF-5 were adsorbed on vCM with great efficiency and continuously delivered in the medium after an initial burst release within hours. We observed statistically significant upregulation of genes encoding the antifibrinolytic thrombomodulin, plasminogen activator inhibitor type 1, thrombospondin 1, and thromboplastin, as well as strong downregulation of genes encoding the profibrinolytic tissue plasminogen activator, urokinase-type plasminogen activator, its receptor, and the matrix metalloproteinase 14 in cells grown on vCM. As a general trend, the stimulatory effect of the vCM on the expression of antifibrinolytic genes was synergistically enhanced by TGF-β1, PDGF-BB, or FGF-2, whereas the strong inhibitory effect of the vCM on the expression of profibrinolytic genes was reversed by PDGF-BB, FGF-2, or GDF-5. Taken together, our data strongly support the effect of the novel vCM on fibrin clot stabilization and coagulation/fibrinolysis equilibrium, thus facilitating progression to the next stages of the soft tissue healing process.     

Biomarkers for Cancer Cachexia: A Mini Review

Cancer cachexia is a common condition in many cancer patients, particularly those with advanced disease. Cancer cachexia patients are generally less tolerant to chemotherapies and radiotherapies, largely limiting their treatment options. While the search for treatments of this condition are ongoing, standards for the efficacy of treatments have yet to be developed. Current diagnostic criteria for cancer cachexia are primarily based on loss of body mass and muscle function. However, these criteria are rather limiting, and in time, when weight loss is noticeable, it may be too late for treatment. Consequently, biomarkers for cancer cachexia would be valuable adjuncts to current diagnostic criteria, and for assessing potential treatments. Using high throughput methods such as “omics approaches”, a plethora of potential biomarkers have been identified. This article reviews and summarizes current studies of biomarkers for cancer cachexia.     

基于连续小波变换的电力系统动态稳定综合评估

提出一种基于连续小波变换的电力系统主导振荡模式、振荡模态、参与因子及同调机群的综合评估方法.首先,借助小波变换实现电力系统多通道广域量测信息的时频域分解,获取各量测通道对应的小波系数矩阵;针对各小波系数矩阵,通过小波功率谱甄别与系统主导振荡模式强相关的关键小波系数向量;然后,利用关键小波系数向量估计系统主导振荡模式的振荡频率和阻尼比;在此基础上,借助交叉小波变换,估计各主导振荡模式下系统的振荡模态;进一步地,根据估计得到的振荡模态,估计系统各量测通道的参与因子和同调机群构成,实现基于连续小波变换的电力系统动态稳定综合评估.利用所提方法对16机68节点测试系统的仿真数据和实际电网的广域实测数据进行分析,结果验证了所提方法的有效性和可行性.     

影响中小企业球铁质量稳定的因素

分析了影响中小企业球铁生产稳定性的关键因素,指出在一定的原材料条件下,目前中小型企业生产球铁存在的问题是温度偏低,孕育方法不当。     

类金刚石膜的制备及其影响因素

概述了近年来制类金刚石膜的新技术如双射频辉光放电（RF－RF）法，射频－直流辉光放电（RF－DC）法和微波－射频（MW－RF）法等，并且对影响类金刚石膜制备及性能的因素如基体材料，制备类金刚石膜时在膜中添加元素，类金刚石膜与基材之间的中间层等进行了较全面的分析。     

埋地钢管热缩套补口材料现场应用状况调查与分析

通过对埋地钢管热缩套补口材料的现场应用状况的调查,分析了腐蚀发生的原因,探讨了改进钢管热缩套补口施工工艺和优化补口结构的方法.