Improved synergetic excitation control for transient stability enhancement and voltage regulation of power systems

This paper proposes decentralized improved synergetic excitation controllers (ISEC) for synchronous generators to enhance transient stability and obtain satisfactory voltage regulation performance of power systems. Each generator is considered as a subsystem, for which an ISEC is designed. According to the control objectives, a manifold, which is a linear combination of the deviation of generator terminal voltage, rotor speed and active power, is chosen for the design of ISEC. Compared with the conventional synergetic excitation controller (CSEC), a parameter adaptation scheme is proposed for updating the controller parameter online in order to improve the transient stability and voltage regulation performance simultaneously under various operating conditions. Case studies are undertaken on a single-machine infinite-bus power system and a two-area four-machine power system, respectively. Simulation results show the ISEC can provide better damping and voltage regulation performance, compared with the CSEC without parameter adaptation scheme and the conventional power system stabilizer.     

microRNA在亨廷顿病中的研究进展

亨廷顿病(Huntington's disease, HD)是神经退行性疾病(neurodegenerative disorders)中一种单基因遗传病,由亨廷顿基因(the huntingtin gene, HTT)第一个外显子中的CAG三核苷酸序列重复扩增引起,尚无法治愈。HTT编码的蛋白产物被称为亨廷顿蛋白(Huntingtin protein, Htt)。突变亨廷顿蛋白(mutated huntingtin protein, mHtt)容易形成聚集体,具有毒性,导致一系列细胞学异常和神经元功能障碍。microRNA(miRNA)在基因转录后水平调控中起重要作用,其表达的改变与HD病理过程有关,成为治疗HD的潜在生物标志物。近年来,对一些特定miRNA在HD中调控机制及靶基因预测方面的研究可为HD提供潜在的治疗方法。本文就miRNA在HD中的相关研究进展进行综述。     

Metabolism of phospholipids in the yeast Schizosaccharomyces pombe

The fission yeast Schizosaccharomyces pombe is an important model organism for the study of fundamental questions in eukaryotic cell and molecular biology. A plethora of cellular processes are membrane associated and/or dependent on the proper functioning of cellular membranes. Phospholipids are not only the basic building blocks of cellular membranes; they also serve as precursors to numerous signaling molecules. In this review, we describe the biosynthetic pathways leading to major S. pombe phospholipids, how these pathways are regulated, and what is known about degradation and turnover of fission yeast phospholipids. This review also addresses the synthesis, regulation and the role of water-soluble phospholipid precursors. The last chapter of the review is devoted to the use of S. pombe for the biotechnological production of value-added lipid molecules.     

平面桁架构建的定日镜面形支撑结构优化及实验

针对反射面成型的复杂影响因素，提出平面桁架构建的定日镜面形支撑结构优化技术路线. 利用模拟仿真、数值计算和优化算法等方法，解析20 m²定日镜面形定义技术路线的4个组成环节：面形规格及宽高比、上弦杆的截面矩、平面桁架组间距的最优值、机加工中工艺控制要点的量化. 试制小型定日镜进行实验，分析光斑形状和能流密度分布特性，并与理想球面形光斑比较，两者的拟合优度大于0.98. 实验结果表明，当反射镜宽高比取1.2，上弦杆截面矩取40 000 mm⁴，桁架组间距取950 mm，上弦杆和斜杆的开孔公差小于0.9 mm时，反射面形的质量提升. 研究从原理和实践上证明了该优化技术路线的可行性.     

Reexamination of the Ergothioneine Biosynthetic Methyltransferase EgtD from Mycobacterium tuberculosis as a Protein Kinase Substrate

Ergothioneine has emerged as a crucial cytoprotectant in the pathogenic lifestyle of Mycobacterium tuberculosis. Production of this antioxidant from primary metabolites may be regulated by phosphorylation of Thr213 in the active site of the methyltransferase EgtD. The structure of mycobacterial EgtD suggests that this post-translational modification would require a large-scale change in conformation to make the active-site residue accessible to a protein kinase. In this report, we show that, under in vitro conditions, EgtD is not a substrate of protein kinase PknD.     

基于ＰＩＤ控制算法的直流微网容错控制方法研究

构建直流微网容错控制对象模型，调节直流微电网的输出回路参数；以输出功率、直流微网的 参考电压、弱电网下系统惯性响应特征等为约束参量，构建直流微网容错控制目标函数，在不同电网强度下 进行直流微网容错控制的参数自整定性调节，采用无功环比例积分控制方法进行直流微网容错寻优分析， 建立模糊 ＰＩＤ控制模型，采用变结构的模糊 ＰＩＤ控制方法进行直流微网容错控制过程中的自适应加权学习 和误差反馈调节，实现直流微网容错控制改进设计。仿真结果表明，采用该方法进行直流微网控制的容错 性能较好，输出稳定性较强，具有较好的直流微网输出增益。     

一种平面结构的V波段上变频器

介绍了平面结构的V波段变频器，该变频器采用平衡变频结构，变频电路主体为平面结构，同时采用了E面探针结构的波导微带转换作为射频信号输出，文中给出了该上变频器的电路软件仿真结果和实测结果以及E面探针波导微带转换的仿真和测试结果，最后给出了该上变频器的实物结构。     

自动交换光网络控制平面功能结构的探讨

文章主要讨论了自动交换光网络(ASON)控制平面的两种不同结构：控制平面在网元外部的结构和控制平面部分集成在网元内部的结构，并对这两种结构进行了比较．