晚清热河避暑山庄河工考述

避暑山庄与热河河工息息相关.利用档案资料系统地考证了清代热河河工舆图"热河城外河山图"的具体绘制时间与作者,并对于其所绘信息进行了解析.全面识读并分析了刊刻于1888年的热河河工碑碣——"避暑山庄宫墙及武列河堤坝各工程碑""武列河西崖大坝岁修章程碑".梳理了该河工舆图、碑碣所记载的河工始末,1884-1888年先后2期...     

基于图像处理的药片包装视觉检测系统滤波算法

目的为了有效滤除药片包装视觉检测系统中的噪声,提升图像清晰度,保证后期图像分割、边缘处理顺利进行。方法针对药片视觉检测图像中存在大量不确定噪声,提出一种自适应模糊神经网络的图像滤波算法。在模糊神经网络结构中引入一个鲁棒性较强的隶属函数,并通过梯度下降法对模糊神经网络中的参数进行优化训练,利用优化后的网络结构对被噪声污染的图像进行滤波处理。结果仿真结果表明,该算法能够在保留较完整的图像边缘和重要细节的前提下,有效滤除药片中的噪声。结论该滤波算法有效提高了药片图像的清晰度,对于后期药片图像分割以及边缘化处理具有重要意义。     

余甘子含片的生产工艺研究

将余甘子压碎,提取果汁,分离苦、涩的物质,提取氨基酸、蛋白质等有效成分进行精制,然后加入一定量的辅料,压成片剂。去除余甘果的苦、涩,保持余甘子的特殊风味、口感及疗效。提高有效成分的功效,服用方便。并应用高效液相色谱、全谱直读等离子体发射光谱仪(ICP)分析余甘子含片的成分,对制取余甘子含片的经济效益进行评价。     

30%氟吗啉水分散片剂防治黄瓜霜霉病

室内及田间试验表明：30％氟吗啉水分散片剂对黄瓜霜霉病有良好的防治效果,田间处理剂量100～200ga．i．／hm^2,对黄瓜霜霉病的防效在81％～97％之间,持效期在10d以上,且对供试作物安全。     

黄栀护肝片的薄层色谱鉴别及含量测定研究

用薄层色谱法对处方中的黄连、栀子、五味子、羌活进行定性鉴别,用高效液相色谱法测定制剂中黄芩苷的含量,色谱条件为：色谱柱为Diamonsil C18（4.6 mm×200 mm,5μm）;流动相为甲醇体积∶水体积∶冰醋酸体积（50∶50∶1）;流速为1 mL.min-1;柱温为35℃;检测波长为274 nm。薄层色谱能检出黄连、栀子、五味子、羌活的特征斑点,黄芩苷在0.354～3.54μg范围内呈良好线性关系,r=0.999 8,平均回收率为99.77%,RSD值为0.32%,5批样品黄芩苷含量平均值为3.92 mg.g-1。结论：本试验建立的方法专属性强,可作为黄栀护肝片的定性定量检测方法。     

关于ZP—33型旋转式压片机压轮机构的改进设计

本文阐述了 ZP-33型旋转式压片机压轮机构中存在的问题,介绍了压片机压轮机构的改进设计.     

Tablet game-supported speech therapy embedded in children’s popular practices

Modern speech-language pathology practices (SLPPs) have adopted tablet games in recent years. Research is needed to take advantage of the potential benefits tablets can offer and to explore the factors that influence its introduction. This paper discusses a survey that was conducted to investigate the factors that influence speech-language pathologists’ (SLPs) beliefs and the actual use of tablets in SLPPs. The results of the survey, conducted among Slovenian SLPs, indicated that their most positive beliefs concerning tablets relate to social influence. Specifically, the beliefs relate to children’s interest and practice with tablets and have a significant impact on the decision-making of SLPs concerning introducing tablets in therapy. Conversely, SLPs’ most negative beliefs relate to the conditions for facilitating tablet use, particularly the lack of Slovenian applications. This paper discusses a separate case study that was conducted in which tablet game-supported therapy was introduced to a group of 44 children. The case study results indicated that the children accepted the use of tablet games for therapy purposes and the games had a positive impact on the children’s motivation and satisfaction.     

Unobtrusive touch‐free interaction on mobile devices in dirty working environments

In this work, we propose a new mode of interaction using hand gestures captured by the back camera of a mobile device. Using a simple intuitive two‐finger picking gesture, the user can perform mouse click and drag‐and‐drop operations from the back of the device, which provides an unobstructed touch‐free interaction. This method allows users to operate on a tablet and maintain full awareness of the display, which is especially suitable for certain working environments, such as the machine shop, garage, kitchen, gym, or construction site, where people's hands may be dirty, wet, or in gloves. The speed, accuracy, and error rate of this interaction have been evaluated and compared with the typical touch interaction in an empirical study. The results show that, although this method is not, in general, as efficient and accurate as direct touch, participants still consider it an effective and intuitive method of interacting with mobile devices in environments where direct touch is impractical.     

Optimal location of the tablet for typing while listening to a song

Tablets are much heavier than smartphones and able to bring more musculoskeletal disorders in the upper extremities. The aim of this study was to understand the effects of tablet location on the recruitment of muscles in the neck and upper extremities. Fifteen healthy volunteers typed the lyrics while listening to a song at three tablet locations for 5 min. An iPad 2 was randomly located at one of the levels with 70, 90, and 130 degrees of elbow flexion in sitting. Typing duration, frequency of typing error, perceived levels of fatigue, and subjective position preferences were recorded and recruitment of muscles in the neck and upper extremities was measured. Muscle recruitment of three parts of the trapezius and biceps brachii decreased and use of the levator scapula increased as the vertical level of the tablet heightened. Self‐reported discomfort increased significantly in the neck, upper back, shoulders, elbows, and wrists over time regardless of the tablet location. The table location affected the self‐reported discomfort only at the elbow joints. Subjective preference was highest at the lowest tablet location with the 130‐degree elbow flexion. The vertical levels of the tablet and typing duration independently affected the muscle recruitment and self‐reported discomfort. Findings of this study can be helpful for tablet users in preventing musculoskeletal disorders in the upper extremities.     

Development and uniform evaluation of ropinirole osmotic pump tablets with REQUIP XL both in vitro and in beagle dogs

REQUIP XL, prolonged release formulation of ropinirole hydrochloride (RH) in market, could release ropinirole constantly and showed satisfactory therapeutic effect and good compliance. REQUIP XL was composed of more than 10 kinds of excipients and prepared by Geomatrix technology, which was complex and laborious. The purpose of this study was to obtain a dosage form of RH with similar in vitro release profile and bioequivalence in vivo compared to REQUIP XL. Osmotic pump tablet combined with fast release phase was selected as the delivery system of RH and similar release curves were obtained in different media. The tablets were also administered to beagle dogs and the pharmacokinetic parameters were calculated using a non-compartmental model. C_max, t_max, mean residence time (MRT), and area under the curve from 0 to 24?h (AUC_0–24) were 3.97?±?0.53?ng/mL, 3.58?±?0.49?h, 8.29?±?0.93?h, and 35.20?±?8.11?ng/mL???h for ropinirole osmotic pump tablets (ROPT) and 4.15?±?1.07?ng/mL, 2.92?±?0.49?h, 7.84?±?1.09?h, and 34.34?±?10.06?ng/mL???h for REQUIP XL. The log-transformed mean C_max and AUC_0–24 of ROPT were about 92.15% and 102.49% relative to that of REQUIP XL, respectively. The 90% confidence intervals of C_max and AUC_0–24 for ROPT were 75.69–115.31% and 88.89–122.30%, respectively. So it could be concluded that ROPT was uniform with REQUIP XL both in vitro and in beagles and the release profiles of Geomatrix technology may be obtained by osmotic pump combined with fast release technology.