凝析油自动计量测控系统的设计

从减小生产工况对凝析油计量的影响、提高计量精度出发,提出了一种集凝析油产量和含水率计量为一体的高精度计量方案,介绍了该自动计量系统测控电路及其软件的设计思路,现场运行与测试表明该自动计量系统原理正确、工作稳定、精度较高。     

多位LED串行显示电路设计与应用

74HC595A芯片具有串行输入、并行输出功能,利用该集成电路可设计多位LED(发光二极管)串行显示电路。文中介绍了利用该芯片设计的12位LED串行显示电路,详细说明了该电路的工作原理及编程思路,并给出了参考程序。该电路只占用单片机3根口线,较并行显示方式极大地节省了系统资源,已在实际系统中得到应用。     

MC68HC908GP32单片机编程器的设计与实现

在分析Motorola M68HC08系列MCU的Flash存储器编程模式基础上，提出了MC68HC908HP32芯片的一种简明而实用的编程器设计方案，给出了基本设计思想，硬件设计电路，软件设计框架，并与Motorola公司提供的电路进行了对比分析。     

HC轧机板形板凸度控制特性的计算机模拟

用三次样条流线条元法分析带材的三维塑性变形，用影响系数法分析辊系的弹性变形用，BP神经网络方法对轧后带材板形进行模式识别，将三者联立，对900mmHC轧机板形板凸度控制特性进行了计算机模拟。结果表明：HC轧机控制二次板形能力很强，对四次及更高次板形控制能力较弱；中间辊横移和工作辊弯辊对板形板凸度的控制需要相互配合。对板凸度的控制应着重在开始道次进行。     

热轧卷取温度对HC340LAD+Z带钢力学性能的影响

为了研究热轧卷取温度对热镀锌HC340LAD+Z带钢力学性能的影响规律,对同一炉次、相同规格的3批次钢坯,分别采用580、620、660 ℃3个卷取温度,以及相同的冷轧、热镀锌、退火工艺进行了试验研究。结果表明,随着卷取温度的升高,成品带钢的屈服强度、抗拉强度降低,伸长率稍有增加,均满足EN10346标准对HC340LAD+Z带钢力学性能的要求。热轧卷取温度为620 ℃时,HC340LAD+Z带钢的屈服强度为389.2 MPa,抗拉强度为474.3 MPa,伸长率A80为26.5%,其综合力学性能对比标准指标,富裕量最佳。     

The in vitro and in vivo investigation of inhaled migraine therapies using a novel aerosol delivery system consisting of an air pressurized capsule device (APCD) in combination with a pMDI spacer for endotracheal dosing into beagle dogs

Abstract

Context: Aerosol delivery to animals in preclinical settings has historically been very challenging, requiring the use of techniques, such as intratracheal instillation and dry powder insufflation, that are somewhat invasive, inefficient and not representative of clinical inhalation.

Objective: The objective of this work is to develop a system to deliver dry powder to dogs in an efficient and effective manner for the study of new anti-migraine compounds in development.

Materials and methods: The new device uses a metered aliquot of a dry gas to force dry powder drug from a pre-filled HPMC capsule into an AeroChamber® spacer for subsequent inhalation by the animal.

Results: The delivery of two invesigational migraine drugs via the new device was assessed in vitro using abbreviated Andersen cascade impaction and showed the device is capable of generating a reproducible delivered dose of up to ～68% with more than 50% of the dose in the respirable range. In vivo studies have also been performed showing that this device effectively delivered the migraine drugs to spontaneously breathing dogs using a proprietary validated dog inhalation model.

Discussion: Results confirmed that the air pressurized capsule device (APCD) was effective in delivering the APIs to lungs of the animals. The in vivo data verified the advantages of inhaled delivery over oral delivery for this class of drugs and were used to establish the cardiopulmonary and respiratory side effect liability profile for these compounds.

Conclusions: This work has demonstrated the utility of this device for quick and accurate screening of prospective drug candidates, representing a significant improvement in ease of use and reprodicibility over current delivery methods.     

超规格宽带钢生产设计

通过对攀钢冷轧厂酸轧机组限制设备进行技改,及对工艺参数、轧制模型进行优化,利用1 220 mm酸轧机组开发生产出超原机组设计（1 120 mm）的宽带钢产品(1 155～1 250 mm)。拓宽了酸轧机组产品结构,满足了镀锌机组及客户要求,节约了成本,提高了合同兑现。     

基于MC68HC08系列单片机下汽车防盗器程序设计

文中具体介绍应用MC68HC08系列单片机的汽车防盗器的功能、硬件组成及原理,采用Protel软件画出电路图、汽车防盗器主程序流程图,并且编写了汽车防盗器汇编语言程序.     

基于GP32的射频读写模块的设计

本文基于模块化设计思想、应用在线编程技术,设计了一种基于Freescale 8位微控制器MC68HC908GP32的射频识别卡Mifare1的读写模块。给出了该模块的设计方案和硬件系统组成,并介绍了其软硬件实现过程。该读写模块不仅能完成对射频识别卡的控制和读写操作,而且可供用户进行二次开发。