Study of viscosity of mono-, di-, and trialkylamines

Viscosities of several mono-, di-, and trialkylamines have been measured in the temperature range 298 to 333 K. It is observed that viscosities are highly dependent on shape, size, and association through H-bond or through dipole. Following the transition state theory, energy, Gibbs free energy, and entropy of activation of viscous flow have been calculated. The values of expansion energy for these liquids have also been calculated using free volume theory, and subsequently amines have been classified as volume-restrained or energy-restrained liquids. The group contribution method of Van Velzen, Cardozo, and Langenkamp for estimating viscosity has been examined with the present and literature data, and the new group contribution increments N _i and B _i for amines have been evaluated.     

车载自组网中一种支持群签名认证的分布式密钥管理方案

群签名具备良好的匿名认证特性,满足车载自组网信息安全和隐私保护需求。但是,其作废开销较大,不适于在大规模网络环境中应用。为此,本文提出了一种支持群签名认证的分布式密钥管理方案DKM,将车载自组网的覆盖区域划分为若干子区域,车辆周期性地从所在子区域的群管理机构更新群密钥。这样,作废某个成员只需要在其拥有合法密钥的子区域内通告,而不是整个网络,有利于降低作废开销。同时,DKM中的密钥更新机制能够保证车辆的群密钥的私密性,从而避免了车辆与区域群管理机构的授权争议,保持了数字签名的不可否认性。性能分析表明DKM能够显著缩短作废列表长度,同时没有增加认证开销。     

Group contributions to activity coefficients from the hard sphere expansion corresponding states theory

A new method has been developed for predicting liquid activity coefficients in ternary mixtures from group contributions. In this method, activity coefficients are obtained from the excess Gibbs free energy of mixing at constant temperature and pressure. In calculating this excess function, the constituent and mixture Gibbs free energies are each represented by an expansion about a pure reference fluid in powers of ratios of hard-sphere diameters and molecular attraction parameters. When the pure component differs from the reference by a single structural group, these ratios represent, respectively, the size contribution and the attraction contribution of this group to the thermodynamic property of the pure fluid. Contributions of intermolecular repulsion to the excess Gibbs free energy are calculated directly from hard-sphere equations of state for the mixture and pure components. The effect of polar contributions calculated by a Padé approximant is also examined. Results indicate that the method developed from the hard-sphere expansion corresponding-states theory is useful for predicting activity coefficients in ternary mixtures when unlike-pair interaction parameters are fitted to binary activity coefficient data. Furthermore, the method shows promise in providing a theoretical basis for applying group contributions to activity coefficients.Nomenclature A Residual Helmholtz free energy - C _p Constant-pressure heat capacity - H _vap Heat of vaporization - P ^s Saturated vapor pressure - R Gas constant - T Temperature - U ^HS Hard-sphere internal energy - V _c Critical volume - V ^L Liquid volume - x Dimensionless residual thermodynamic property - Z Compressibility factor - d Center-to-center distance between two touching molecules - k Boltzmann constant - n Moles - x Liquid mole fraction - y Vapor mole fraction - Volume expansivity - Liquid activity coefficient - Minimum molecular attraction potential - Isothermal compressibility - Permanent dipole moment - 3.14159... - Density - Fugacity coefficient Paper presented at the Ninth Symposium on Thermophysical Properties, June 24–27, 1985, Boulder, Colorado, U.S.A.     

强隐私保护的移动群智感知方案

为了实现移动群智感知系统中身份隐私、证书撤销和积分激励功能,同时解决恶意用户身份追踪与诚实用户隐私保护之间的矛盾,提出了强隐私保护的移动群智感知方案.基于门限密码思想将身份追踪能力分散到多个实体上,使得多个追踪者合作才能追踪用户身份;将Pointcheval-Sanders签名和基于RSA假设的Camenisch-Lysyanskaya累加器结合起来实现了证书的安全快速撤销;利用Pointcheval-Sanders签名构造了保护隐私的积分激励机制.对该方案进行了安全性分析和实验分析.研究结果表明,该方案不仅满足安全要求,而且在实际应用中具有可行性.     

敞口管型桩压入对既有受荷桩基承载性状影响

基于经典桩侧摩阻力公式和圆孔扩张理论,优化考虑土压力系数、土塞增长率、扩孔塑性半径等问题,计算新增管桩的植入对在役桩承载性状的影响. 对比分析有限元的软件与理论计算结果,发现管型桩贯入引致的桩间土挤土效应,使在役桩侧摩阻力在一定深度范围内增加,且桩长越长、桩间距越小,贡献越明显. 新增桩与在役桩的距离小于3倍桩径,会形成局部群桩效应,使群桩协同工作时的桩顶沉降增加;距离大于6倍桩径,管型桩压入对既有桩侧摩阻力、群桩协同工作效应的影响较小.     

一种基于RSA安全可行的（t，n）门限签名方案*

分析了大多数RSA门限群签名方案存在的缺陷,RSA的模数是n,φ(n)是秘密参数,参加部分签名的成员无法知晓,求Lagrange相关系数存在困难,也为建立门限RSA密码体制带来困难.提出一种新的方案以克服上述困难,通过求ai无须在求Lagrange相关系数时进行求逆运算,使该方案在保证安全的前提下变得可行实用.     

基于身份的指定验证者代理签名方案*

在代理签名中,原始签名人能将其数字签名权力委托给代理签名人;在指定验证者签名方案中,只有事先指定的验证者才能验证签名的有效性.综合上述两种方案的优点,利用Weil对的双线性映射,构造了一个基于身份的指定验证者代理签名方案,并对其安全性进行简要的分析.     

改进的代理多重签名方案*

Ji和Li提出的一种基于椭圆曲线离散对数问题的代理多重签名方案存在两个问题：a）安全性,该方案的签名验证数据中没有避免孤悬因子这一现象,因此并不满足强不可伪造性,任意一个原始签名者能伪造代理多重签名;b）效率,代理多重签名的长度和验证其签名效率与原始签名者的个数有关。对Ji-Li代理多签名方案的安全性和效率进行了分析,提出了新的、安全的基于椭圆曲线离散对数问题的代理多签名体制,提高了签名验证效率、缩短了签名长度。     

一种基于身份的群签名方案*

群签名使得群中任何一个成员均可以代表该群进行签名,而不会暴露签名者的身份.当争议发生时,签名者的身份可以通过群管理员公开.基于身份的签名与群签名有许多相似性,给出了一个由基于身份的签名转换而来的群签名,并给出了它在电子选举中的应用实例.     

Design,Synthesis and Biological Evaluation of Steroidal Glycoconjugates as Potential Antiproliferative Agents

To systematically evaluate the impact of neoglycosylation upon the anticancer activities and selectivity of steroids, four series of neoglycosides of diosgenin, pregnenolone, dehydroepiandrosterone and estrone were designed and synthesized according to the neoglycosylation approach. The structures of all the products were elucidated by NMR analysis, and the stereochemistry of C20-MeON-pregnenolone was confirmed by crystal X-ray diffraction. The compounds′ cytotoxicity on five human cancer cell lines was evaluated using a Cell Counting Kit-8 assay, and structure–activity relationships (SAR) are discussed. 2-deoxy-d -glucoside 5 k displayed the most potent antiproliferative activities against HepG2 cells with an IC₅₀ value of 1.5 μM. Further pharmacological experiments on compound 5 k on HepG2 cells revealed that it could cause morphological changes and cell-cycle arrest at the G0/G1 phase and then induced the apoptosis, which might be associated with the enhanced expression of high-mobility group Box 1 (HMGB1). Taken together, these findings prove that the neoglycosylation of steroids could be a promising strategy for the discovery of potential antiproliferative agents.