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61.
In this work, the effect of ZrB2 (0, 5, 10 and 20?vol%) ceramic reinforcement on densification, structure, and properties of mechanically alloyed Al was investigated. The milling of Al-ZrB2 powder compositions resulted in formation of agglomerates with varied size. In particular, the size of agglomerates was reduced considerably with increased addition of ZrB2 to Al. Interestingly, the densification of hot pressed Al increased from 96.06% to 99.22% with ZrB2 addition. The reduction of agglomerates size was attributed to the enhanced densification of Al-ZrB2 composites. Pure Al showed relatively low hardness (0.94?GPa) and it was improved to 1.78?GPa with the addition of 20?vol% ZrB2. The mechanical properties have significantly been improved for Al-ZrB2 composites. Especially Al - 20?vol% ZrB2 possessed a very high yield strength (529?MPa), compressive strength (630?MPa) and compressive strain of 19.25%. Realization of such a good combination of mechanical properties is the highest ever reported for Al composites so far in the literature. The coefficient of friction (COF) of Al-ZrB2 varied narrowly between 0.33 and 0.40 after dry sliding wear against steel disc. The wear rate of Al-ZrB2 composites was within mild wear regime and varied between 98.88?×?10?6 and 34.66?×?10?6 mm3/Nm. Among all the compositions, Al - 20?vol% ZrB2 composite exhibited the lowest wear rate and high wear rate was noted for pure Al. Mild abrasion, tribo-oxidation, third body wear (wear debris) and delamination were the major material removal mechanisms for Al-ZrB2 composites. Overall the hardness, strength and wear resistance of Al - 20?vol% ZrB2 composite was improved by 84.3%, 84.3% and 64.2%, respectively when compared to pure Al.  相似文献   
62.
ABSTRACT

A mathematical model has been developed by coupling genetic algorithm (GA) with heat and material balance equations to estimate rate parameters and solid-phase evolution related to the reduction of iron ore-coal composite pellets in a multi-layer bed Rotary hearth Furnace (RHF). The present process involves treating iron ore-coal composite pellets in a crucible over the hearth in RHF. The various solid phases evolved at the end of the process are estimated experimentally, and are used in conjunction with the model to estimate rate parameters. The predicted apparent activation energy for the wustite reduction step is found to be lower than those of the reduction of higher oxides. The thermal efficiency is found to decrease significantly with an increase in the carbon content of the pellet. Thermal efficiency was also found to increase mildly up to three layers. Multilayer bed remains as a potential design parameter to increase thermal efficiency.  相似文献   
63.
Many argue that digital technologies have the potential to enhance the teaching and learning of mathematics. However, the availability of technology is not sufficient to realise this potential. The study reported takes a detailed approach to investigate the utility of the particular offerings of the available technologies in the teaching and learning of a specific area of mathematics, functions. Sixteen affordances identified in the data are described. The complexity of the process involved in resolving a situation where particular affordances would be useful so as they are perceived and enacted is detailed. Finally, a grounded theory framework arising from the data analysis from this study that can be used to explain, predict and guide action in other digital environments is presented.  相似文献   
64.
Production planning and control (PPC) systems that employ aspects from both make-to-order (MTO) and make-to-stock (MTS) production control are known as hybrid MTS/MTO systems. While both MTO and MTS separately have been studied extensively, their combined use has received less attention. However, the literature on this topic is growing and this paper shows that the review performed in this paper is an important addition to the field. We categorise relevant literature according to a novel taxonomy and show that hybrid MTS/MTO production control can be used in different contexts. In addition, an overview of the modelling techniques and methods used in these papers is provided. Based on the reviewed literature, relevant research questions and directions for future research are identified. Finally, it is shown that hybrid MTS/MTO production control is prevalent in practice by discussing research with industrial applications. The paper contains an overview of research on hybrid MTS/MTO production control to be used as reference for researchers active in the field, and provides managerial insights and directions for future research on this topic.  相似文献   
65.
The mammalian cell cycle is important in controlling normal cell proliferation and the development of various diseases. Cell cycle checkpoints are well regulated by both activators and inhibitors to avoid cell growth disorder and cancerogenesis. Cyclin dependent kinase 20 (CDK20) and p21Cip1/Waf1 are widely recognized as key regulators of cell cycle checkpoints controlling cell proliferation/growth and involving in developing multiple cancers. Emerging evidence demonstrates that these two cell cycle regulators also play an essential role in promoting cell survival independent of the cell cycle, particularly in those cells with a limited capability of proliferation, such as cardiomyocytes. These findings bring new insights into understanding cytoprotection in these tissues. Here, we summarize the new progress of the studies on these two molecules in regulating cell cycle/growth, and their new roles in cell survival by inhibiting various cell death mechanisms. We also outline their potential implications in cancerogenesis and protection in heart diseases. This information renews the knowledge in molecular natures and cellular functions of these regulators, leading to a better understanding of the pathogenesis of the associated diseases and the discovery of new therapeutic strategies.  相似文献   
66.
Due to the law of reflection, a concave reflecting surface/mirror causes the incident light rays to converge and a convex surface/mirror causes the light rays to reflect away so that they all appear to be diverging. These converging and diverging behaviors cause that the curved mirrors show different image types depending on the distance between the object and the mirror. We model such optical phenomena metaphorically into the searching process of numerical optimization by a new algorithm called optics inspired optimization (OIO). OIO treats the surface of the numerical function to be optimized as a reflecting surface in which each peak is assumed to reflect as a convex mirror and each valley to reflect as a concave one. Each individual is assumed to be an artificial object (or light point) that its artificially glittered ray is reflected back by the function surface, given that the surface is convex or concave, and the artificial image is formed (a candidate solution is generated within the search domain) based on the mirror equations adopted from physics of optics. Besides OIO, we introduce different variants of it, called ROIO (Rotation based OIO), and COIO (Convex combination based OIO) algorithms and conduct an extensive computational effort to find out the merit of the new algorithms. Our comparisons on benchmark test functions and a real world engineering design application (i.e., optimization of a centrifuge pump) demonstrate that the new algorithms are efficient and compete better than or similar to most of state of the art optimization algorithms with the advantage of accepting few input parameters.  相似文献   
67.
The micromechanics models for composites usually underpredict the tensile strength of polymer nanocomposites. This paper establishes a simple model based on Kelly–Tyson theory for tensile strength of polymer/CNT nanocomposites assuming the effect of interphase between polymer and CNT. In addition, Pukanszky model is joined with the suggested model to calculate the interfacial shear strength (τ), interphase strength (σi) and critical length of CNT (Lc).The proposed approach is applied to calculate τ, σi and Lc for various samples from recent literature. It is revealed that the experimental data are well fitted to calculations by new model which confirm the important effect of interphase on the properties of nanocomposites. Moreover, the derived equations demonstrate that dissimilar correlations are found between τ and B (from Pukanszky model) as well as Lc and B. It is shown that a large B value obtained by strong interfacial adhesion between polymer and CNT is adequate to reduce Lc in polymer/CNT nanocomposites.  相似文献   
68.
《Ceramics International》2019,45(15):18972-18979
Kaolin/graphene oxide composite has been widely utilized in aero-space and architectural engineering applications due to its excellent mechanical property. Direct ink writing (DIW) is a freeform rapid prototyping technology that could be used to accurately fabricate the resulting size with complex shapes. In this study, we reported the DIW of kaolin/graphene oxide (GO) composite suspensions (KGCS) to assemble 3D structures at ambient temperature for the first time. The effects of GO on the chemical constitution and microstructure of kaolin suspensions were investigated. Rheology was characterized to ensure printability of KGCS. The addition of GO in kaolin suspensions quickened a flocculation structure, which dramatically changed their rheology properties. The DIW of 3D structures from the optimal KGCS sample maintained their initial shape without spreading. The flexural and compressive strengths of the dried optimal KGCS samples were obviously enhanced due to the improvement and reduction of the micro-defects compared from cured kaolin matrix.  相似文献   
69.
The mechanisms by which neoplastic cells disseminate from the primary tumor to metastatic sites, so-called metastatic organotropism, remain poorly understood. Epithelial–mesenchymal transition (EMT) plays a role in cancer development and progression by converting static epithelial cells into the migratory and microenvironment-interacting mesenchymal cells, and by the modulation of chemoresistance and stemness of tumor cells. Several findings highlight that pathways involved in EMT and its reverse process (mesenchymal–epithelial transition, MET), now collectively called epithelial–mesenchymal plasticity (EMP), play a role in peritoneal metastases. So far, the relevance of factors linked to EMP in a unique peritoneal malignancy such as pseudomyxoma peritonei (PMP) has not been fully elucidated. In this review, we focus on the role of epithelial–mesenchymal dynamics in the metastatic process involving mucinous neoplastic dissemination in the peritoneum. In particular, we discuss the role of expression profiles and phenotypic transitions found in PMP in light of the recent concept of EMP. A better understanding of EMP-associated mechanisms driving peritoneal metastasis will help to provide a more targeted approach for PMP patients selected for locoregional interventions involving cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.  相似文献   
70.
Investigation of ink formulation options with the purpose to obtain color-gamut-optimal set of Cyan Magenta and Yellow CMY inks is reported. Implementation of the thickness dependent Kubelka-Munk model on multiple ink layers having different and well-defined thicknesses, provides characteristic absorption and scattering (K, S ) spectra of the ink ingredients. These data enable accurate computation of the reflectance spectrum and thus the L*a*b* color coordinates for any given ink thickness or substrate. Pigment materials investigated are quinacridone as magenta, copper-phthalocyanine as cyan, and arylide yellow. Scaling the peak of the absorption band to the number of molecules per unit area for the specific pigments studied in this article provides the molar extinction coefficients, 1.21 × 104 , 4.7 × 104 , and 3.3 × 104 cm2/millimole respectively, regardless of the different ink formulations used, in accord with Avogadro's principle. Having a set of three pairs of K, S spectra is used to compute the color gamut of any CMY color combination in the L*a*b* space as a function of ink layer thickness and formulation. Using an iterative algorithm, a color-gamut-optimal set of CMY inks is obtained.  相似文献   
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