几种吸附式致冷新工质对的性能预测

应用吸附平衡基本理论对几种可能的吸附式致冷新工质对的性能进行了预测。结果表明，烷烃系列的低混点工质与沸石的配对体系是不可取的，而沸石－氨、活性炭－丙酮、活性炭－氨及活性炭－乙醇则是沸石－水、活性炭－甲醇体系的适宜的替代物。     

载银无机抗菌剂变色抑制剂研发现状

介绍了载银无机抗菌剂变色抑制剂如甲基苯并三唑、天然水滑石和合成水滑石等的研发现状     

Identifying a putative common binding site shared by substance P receptor and an anti-substance P monoclonal antibody

Substance P G-protein coupled receptor and the antigen recognitionsite of a monoclonal antibody raised against substance P sharea stretch of five contiguous identical amino acids. This observationprompted us to build an atomic model of both the receptor andthe antibody and to analyse their common features. In particular,we report here that a pocket of similar size and compositionis present in both proteins, strongly suggesting a similarityin the mode of binding of both macromolecules to substance P.From the analysis of our models, the available data on the modeof binding of the antibody to substance P and recent data onsubstance P receptor mutants, we concluded that the pocket isvery likely to be involved in binding of the C-terminal 'messagesequence' of the tachykinin. This allowed us to suggest specificsite-directed mutants of the receptor which should shed somelight on the mechanism of peptide recognition by G-protein coupledreceptors.     

THz-TDS signal analysis and substance identification via the conformal split

A terahertz time-domain spectroscopy(THz-TDS)imaging system can obtain high-dimensional signals with substance fingerprint information.By introducing geometric algebra,a novel signal analysis approach to THz-TDS signals is developed based on an optical physical mechanism.Using this approach,signals are represented with vectors in the high-dimensional real vector space.Geometric distribution properties and algebraic relationships of THz-TDS signals are deduced.It is proved that every complex refractive index of substances relates to a unique 2-blade,the vectors corresponding to the samples of the same substance are collinear and belong to the intrinsic 2-blade of the substance.When decomposed through the conformal split with respect to a 2-blade,THz-TDS signals of high dimensionality can be related to vectors in a 2-dimensional subspace.Based on the conformal split properties we deduced,two criteria for substance identification on the basis of THz-TDS signals are proposed.Accordingly,a novel substance identification method via the conformal split is presented.In the method,the 2-blade related to each "known" substance is calculated with two vectors corresponding to THz-TDS signals measured from samples of the substance but with dierent thicknesses.Using the conformal split with respect to those 2-blades,an identified vector corresponding to a THz-TDS signal is linearly related to the vector in a 2-dimensional subspace.The substance of a sample can be identified using criteria on the projected vectors in the subspaces.This method can contribute to accurate classification and identification.Finally,two experiments are presented that show the feasibility and accuracy of this method.     

Improving antibacterial,biocompatible, and reusable properties of polyvinyl chloride via the addition of aluminum alkoxides

Global bacterial infections associated with conventional polyvinyl chloride (PVC) medical devices place a heavy burden on healthcare systems and thus it will be desirable if medical devices are made from antimicrobial PVC. There are numerous studies focusing on polymer surface modifications to either leach antimicrobial agents or kill pathogenic microbes upon direct contact. In this work, mannitol fumarate ester-based aluminum metal alkoxide (MFE-Al) additive was developed to confer simultaneously improved antibacterial property and enhanced high temperature sterilization resistance of the resultant PVC. Data obtained confirm that the MFE-Al stabilized PVC sheets significantly inhibit 98% bacterial growth. They also show biocompatibility with cultured H9C2 cardiomyocytes and hemocompatibility in vitro. Dry heat sterilization is generally not suitable for PVC medical wares due to their poor thermal compatibility. Surprisingly, our antimicrobial-biocompatible PVC can maintain stability at 180°C for 90 min. Such a high thermal stability indicates the MFE-Al stabilized PVC can endure 90 cycles of dry-heat sterilization without significant damage. This study may provide a solution to reduce PVC medical waste for a maximum benefit without compromising human health or the environment.     

仿生黏附性聚多巴胺丁香酚抑菌微胶囊的制备

以丁香酚（EO）为芯材,多巴胺（DA）为壳材,通过乳液模板-界面聚合法成功制备出尺寸可控的聚多巴胺丁香酚（PDA@EO）微胶囊。通过FTIR、TG、UV-Vis、SEM和TEM对微胶囊的化学结构、形貌、粒径及性能进行表征和分析,结果表明,所制备的微胶囊呈规整球形,粒径在55～94 nm之间,丁香酚包封率为25.35%,包封量为0.6288 g/g,24 h时累积释放率达到68.39%。通过对比实验证明,PDA@EO微胶囊在不同材料表面均具有优异的黏附性能;作用于口腔感染部位常见细菌金黄色葡萄球菌和大肠杆菌24 h,PDA@EO微胶囊较游离丁香酚的抑菌活性分别提高了36.84%和35.52%;当微胶囊质量浓度达到2.0 g/L时,PDA@EO微胶囊对两种细菌的抑菌活性均达到99%以上。     

Poly(chitosan-ester-ether-urethane) Hydrogels as Highly Controlled Genistein Release Systems

Polymeric hydrogels play an increasingly important role in medicine, pharmacy and cosmetology. They appear to be one of the most promising groups of biomaterials due to their favorable physicochemical properties and biocompatibility. The objective of the presented study was to synthesize new poly(chitosan-ester-ether-urethane) hydrogels and to study the kinetic release of genistein (GEN) from these biomaterials. In view of the above, six non-toxic hydrogels were synthesized via the Ring-Opening Polymerization (ROP) and polyaddition processes. The poly(ester-ether) components of the hydrogels have been produced in the presence of the enzyme as a biocatalyst. In some cases, the in vitro release rate of GEN from the obtained hydrogels was characterized by near-zero-order kinetics, without “burst release” and with non-Fickian transport. It is important to note that developed hydrogels have been shown to possess the desired safety profile due to lack of cytotoxicity to skin cells (keratinocytes and fibroblasts). Taking into account the non-toxicity of hydrogels and the relatively highly controlled release profile of GEN, these results may provide fresh insight into polymeric hydrogels as an effective dermatological and/or cosmetological tool.     

Facile Fabrication of Povidone Iodine-Embedded Polytetrafluoroethylene Superhydrophobic Films with Improved Antiadhesive and Bactericidal Properties in Bacterial Environments

It remains a challenge to maintain the antiadhesion properties of superhydrophobic films after exposure to bacterial environments. In this work, superhydrophobic bactericidal polymer films via the simple incorporation of polyvinylpyrrolidone-iodine (PVP-I) or iodine into polytetrafluoroethylene (PTFE) are fabricated to improve their antiadhesive and antibacterial capability. Superhydrophobic iodine-embedded films, polytetrafluoroethylene/polyvinylpyrrolidone-iodine and polytetrafluoroethylene-iodine (PTFE/PVP-I and PTFE-I), show excellent antiadhesive and bactericidal performances even post exposure to bacterial solutions as compared to iodine-free counterparts by controlling the release of iodine. Especially, superhydrophobic PTFE/PVP-I films display a more sustained iodine release profile and significant antibacterial properties against gram-positive (S. aureus, methicillin-resistant S. aureus (MRSA)) and gram-negative (E. coli) bacteria. Such a facile combination of antiseptic agents and superhydrophobic surface could be widely used for antiseptic biomedical applications.     

Facile Deposition of Silver Nanoparticles on Photonic Cellulose Nanocrystals Films: A Study on Solvent Stability and Post Antibacterial Activity

Cellulose nanocrystals (CNCs) incorporated with silver nanoparticles (AgNPs) photonic films have drawn considerable attention due to their plasmonic chiroptical activity. However, the exploitation of some fundamental properties for practical use such as the affinity analysis of metal nanoparticles attached to the surface of photonic films according to the solvent compatibility and antibacterial activity under physical conditions has yet not been studied. Hence, a facile process of in situ deposition of AgNPs into the chiral structure of CNC films is proposed. CNC photonic films, cross-linked by glutaraldehyde are prepared. This interaction generated the solvents-stable photonic film with a considerable amount of unreacted aldehyde functional groups that facilitates the reduction of Ag salt to AgNPs. The formed AgNPs in the photonic films show excellent stability over immersion in various polar and non-polar solvents. The post-solvent treated photonic films display excellent contact-based antibacterial behavior against gram-negative Escherichia coli.