Preparation of porous poly(lactic acid)/Sio2 hybrid microspheres

With 3‐aminopropyltriethoxysilane (APTES) as coupling agent, poly(lactic acid) (PLA)/SiO₂ hybrid material was prepared to produce poly(lactic acid)/SiO₂ hybrid microspheres (PLAHs) with porous structure bythe oil‐in‐water, single‐emulsion solvent evaporation method. Field scanning electron microscopy results show that the PLAHs were porous microspheres about 20 μm in diameter. The holes in the PLAHs opened outside and were not complicated. A nitrogen adsorption–desorption experiment showed that the nitrogen adsorbed in the holes was easily desorbed, and the specific surface area of the PLAHs was calculated to be 6.87 m²/g according to the Brunauer–Emmett–Teller equation. Fourier transform infrared spectroscopy results show that PLA was amidated with APTES successfully and formed a kind of organic–inorganic hybrid material by hydrolysis and con‐condensation with tetraethoxysilane. Moreover, the molecular structure of the hybrid material was confirmed by X‐ray photoelectron spectroscopy. Differential scanning calorimetry results show that the melting point ofthe PLAHs was higher than that of PLA by about 11.2°C. These PLAHs may be used in the controlled release of drugs by the embedding of the drugs in the holes of the PLAHs, and the drug loading amount can be controlled by the size and number of holes in the PLAHs. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 679–683, 2006     

桂柳高速公路两侧土壤重金属分布特征

选择桂柳高速公路上的4个调查剖面和1个对照剖面测试了公路两侧农田土壤中Pb、Cd、Cr、Hg和As的含量分布。结果表明,公路交通对路两侧土壤重金属含量有一定的影响,运行期较长的对照路段桂黄公路两侧土壤中的Pb、Cd和As的含量明显高于运营期较短的桂柳高速公路段,而Cr、Hg与公路运行期长短的关系不是非常密切;重金属含量在横向上都有随距路肩距离的减小而增大的趋势,Pb、Cd在路肩两侧200m范围内含量的变化较小。以广西水稻土土壤背景值为评级标准,采用单因子指数法评价了路侧土壤的环境质量：所测路段和剖面的Cd、Hg污染均较严重;Cr基本上还处在非污染水平;桂黄公路段Pb的污染指数高于高速公路段。     

一种求解网损因子的新方法

从耗散功率转归理论所提出的支路功率损耗公式出发,分别针对考虑与不考虑节点注入无功功率对有功功率损耗的影响两种情况下,推导出了用于求解系统总的有功损耗、各节点应当分摊到的有功损耗、节点网损因子的新公式。与传统求解方法相比,该方法完全依靠支路的参数,物理含义清晰,更易于计算。     

张家口地区电子文献传递系统(EDDS)的开发研究

随着人们对信息资源的需求及文献传递工作的重视,文献传递的服务模式及发展趋势逐渐成为社会所关注的问题.本课题通过分布式文献传递的服务模式,利用完备的网络搜索系统模型,构建张家口地区高校图书馆之间的电子文献传递桥梁.     

基于距离门限的水声网络自适应路由协议

针对水声传感器网络长时延和高能耗的问题,提出了基于距离门限的自适应路由协议ARBDT（AdaptiveRouting Protocol Based on Distance Threshold）。该协议采用单路径逐跳信息传输方式,节省了路由开销;同时根据网络密集程度自适应地调整距离门限,抑制了冗余节点的回应,降低了控制包冲突的概率,使发送节点能快速获取转发节点。仿真结果表明,与SBR（Sector-Based Routing）协议相比,ARBDT协议能缩短时延,降低网络能耗,从而获得更好的性能。     

Cephazoline sodium release from poly(N‐isopropyl acrylamide‐co‐N,N‐dimethylacrylamide) hydrogels

Hydrogels are hydrophilic polymers that swell to an equilibrium volume in the presence of water, preserving their shape. The dynamic swelling behavior of poly(N‐isopropylacrylamide‐co‐N,N‐dimethylacrylamide) [poly(NIPA‐co‐DMA)] copolymers at 37°C was investigated. It was observed that the swelling degree in the copolymers decreases with the N‐isopropylacrylamide content. In addition, the liberation mechanism was found to be Fickian. Diffusion coefficients according to Fick′s law as a function of the N‐isopropylacrylamide concentration and results of the release process are reported. The kinetics of cephazoline sodium release from poly(NIPA‐co‐DMA) hydrogels with different compositions was studied. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 91: 3433–3437, 2004     

Effect of montmorillonite on the swelling behavior and drug‐release behavior of nanocomposite hydrogels

A series of nanocomposite hydrogels were prepared from various ratios of N‐isopropylacrylamide (NIPAAm) and organic montmorillonite (MMT). The influence of the extent of MMT in the NIPAAm/MMT nanocomposite hydrogels on the physical properties and drug‐release behavior was the main purpose of this study. The microstructure and morphology were identified by X‐ray diffraction (XRD) and scanning electronic microscopy (SEM). The results showed that the swelling ratios for these nanocomposite hydrogels decreased with increase in the content of MMT. The gel strength and Young's modulus of the gels also increased with increase in the content of MMT. XRD results indicated that the exfoliation of MMT was achieved in the swollen state. Finally, the drug‐release behavior for the gels was also assessed. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 3652–3660, 2003     

Preparation and characterization of chitosan-poly(acrylic acid) polymer magnetic microspheres

A modified method to prepare chitosan-poly(acrylic acid)(CS-PAA) polymer magnetic microspheres was reported in this paper. First, via self-assembly of positively charged CS and negatively charged Fe₃O₄ nanoparticles, magnetic CS cores with a large amount of Fe₃O₄ nanoparticles were successfully prepared. Subsequently, the AA monomers were polymerized on the magetic CS cores based on the reaction system of water-soluble polymer-monomer pairs. These polymer magnetic microspheres had a high Fe₃O₄ loading content, and showed unique pH-dependent behaviors on the size and zeta potential. From the magnetometer measurements data, the CS-PAA polymer magnetic microspheres also had superparamagnetic property as well as fast magnetic response. A continuous release of the entrapped ammonium glycyrrhizinate in such polymer magnetic microspheres occurred, which confirmed the potential applications of these microspheres for the targeted delivery of drugs.     

求解需求可拆分车辆路径问题的改进的金字塔演化策略

为了更加合理地求解需求可拆分的车辆路径问题（SDVRP）,克服传统先路径后优化两阶段的求解方法容易陷入局部最优的缺点,以及解决智能优化算法在优化阶段未能将竞争与协作有机地融合为一体的问题,以配送路径最短和配送车辆最少为优化目标,提出了一种改进的金字塔演化策略（IPES）。首先,以金字塔为基础,提出了求解SDVRP的编码、解码方式以及层级间的协作策略;其次,根据遗传算法的随机、“适者生存”的高度并行、自适应等特点,以及金字塔结构各层分工不同,设计了一种适合SDVRP的自适应邻域算子,使得算法能够快速收敛到最优;最后,得到最优解。相较于分段求解算法、聚类算法、粒子群算法、人工蜂群算法、禁忌搜索算法,四个仿真实验的结果表明,在求解各案例的最优路径时,所提IPES的求解精度分别至少提升了0.92%、0.35%、3.07%、9.40%,验证了在求解SDVRP时,IPES具有良好的性能。     

多时空配送任务驱动的无人车队车辆数优化方法

为解决快递终端配送多时空任务驱动下的最小无人车队车辆数配置问题,提出一种随机优化方法。首先,分析服务时长和等待时长对无人车队行驶路线规划的影响,从而构建最短路径模型;然后,基于二维时空网络构造服务序列网络;其次,通过网络转换将最小无人车队车辆数配置问题转化为网络最大流问题,并建立以车队车辆数最小为目标的最小车队模型;最后,针对模型特征设计一种融合Dijkstra算法和Dinic算法的Dijkstra-Dinic算法来对最小无人车队车辆数配置问题进行求解。在四种不同规模的服务网络中进行仿真实验,实验结果表明：在不同成功服务率下,最小无人车队车辆数与服务网络规模呈正相关,但随等待时长的增加而减少并趋向于稳定;所提算法中所引入的One-stop算子大大提高了搜索效率,所提模型和算法适用于大规模服务网络中的最小车队计算。