Onset of gas self-induction and power consumption after gas induction in an agitated tank

The behavior of inducted gas from liquid surface and the; power requirements in an agitated tank using a mechanical agitator are studied in order to increase the amount of gas self-induction and the gas retention time for gas absorption. A 45° six-blade downward impeller turbine was utilized in this study. Air and water, air and 40 wt% 60 wt%, and 80 wt% of glycerin water, and air and 106 cP silicon oil were employed as gas and liquid phases. Variables which were studied included geometrical factors (immersed depth of impeller, baffle with and diameter of impeller) and the physical properties of the liquid (viscosity, density, and surface tension). The correlations for the onset speed of impeller and power consumption after gas induction in the agitated tank are established from our experimental results. The amount of gas self-induction from the liquid surface in the agitated tank increases with increasing impeller diameter and speed and decreases with increasing baffle width, depth of impeller and viscosity of liquid.     

三辊穿孔和轧管所产生的钢管壁厚极差和波浪形内螺纹

定量描述了实际生产过程中三辊斜轧穿孔所产生的钢管壁厚极差和波浪形内螺纹，初步探讨了三辊轧管机对钢管壁厚极差和波浪形内螺纹的影响。     

用双向扭转圆柱组合螺旋弹簧实现扭矩测试

利用单个圆柱螺旋扭转弹簧扭转原理,给出了一种用双向扭转圆柱组合螺旋弹簧实现扭矩测试的方法。根据扭转弹簧模型,给出了预紧力、加载的证明,并对实验结果进行分析;该结构用于扭矩测试系统既实用可靠,又简单易加工;降低了测试系统的成本,具有很高的实用价值。     

胆甾相液晶的光学特性

基于胆甾相液晶的特殊分子结构，综合阐述了胆甾相液晶的旋光性、选择性光散射和偏振光二色性等光学特性，揭示了它的光学特性主要源于它螺旋状的分子结构及其光学各相异性。     

幂律流体同心环空螺旋流数值模拟

环空螺旋流是钻井液在钻井作业中常见的一种流型，怎样方便、快速及高精度地计算其流速场与压力梯度是一个重要工程问题。提出直接利用线性化迭代法求解幂律流体在环空中螺旋流的流场及压力梯度，避免了求解非线性方程组而可能出现迭代发散的问题，该线性化迭代算法真实可信，精确度高。使用线性化迭代算法，仅以求解两个三对角线性方程组为一次循环，运算速度快，占用时间少，精度高，收敛性得到可靠保证，是矿场使用的好方法，为矿场作业中水力参数设计提供了科学依据。     

Interconnected power systems with superconducting magnetic energy storage

The objective of this work is to discuss the concept of back‐to‐back interconnection systems with energy storage, especially with a Superconducting Magnetic Energy Storage (SMES) incorporated into a back‐to‐back DC link. In this case, each converter of the back‐to‐back system is used as a power conditioning system for the SMES coils. Since the AC–DC converter can be designed independently of the frequency of the power system, a two‐way switch is connected to the AC side of each converter. This two‐way switch can select the interconnected power systems. By using the two‐way switches, this system can provide the stored energy in the SMES system to each interconnected power system through two AC–DC converters. For instance, lower‐cost power of each power network can be stored through two converters during the off‐peak hours and made available for dispatch to each power network during periods of demand peak. Then this system increases the reliability of electric power networks and enables the economical operations depending on the power demand. This paper describes the unique operations of the back‐to‐back interconnection with SMES and discuses the optimal SMES configuration for a 300‐MW‐class back‐to‐back interconnection. © 2008 Wiley Periodicals, Inc. Electr Eng Jpn, 164(2): 37–43, 2008; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/eej.20482     

螺旋弹簧的非线性理论及实验研究

本文通过对经典的圆柱螺旋弹簧理论的修正,给出了非线性理论解析公式.还通过对螺旋弹簧的精确测量和处理,验证了本文的非线性理论.     

圆柱形螺旋弹簧的简捷计算

将圆柱形螺旋弹簧设计中的部分常用公式组合成一组仅与弹簧指数Ｃ有关的公式，并将Ｃ＝４～１４代入计算而获得一套参数表，由此，可提高圆柱形螺旋弹簧的设计效率。     

组合隔板式鱼道水力特性数值模拟研究

鱼道是为鱼类提供洄游通道的一种重要的工程措施。基于Flow-3D采用标准RNG k-ε紊流模型和Tru-VOF追踪自由液面方法,对鱼道池室内流场进行三维紊流数值模拟,研究池室内水流流速、流态空间分布,分析鱼道的水力特性对目标鱼类洄游上溯的影响。结果表明:溢流堰与竖缝组合隔板式鱼道在设计流速v=0.75 m/s条件下,竖缝处平均流速为0.83 m/s,竖缝处流速分布范围为0.76~0.89 m/s;堰上流速为0.90~1.12 m/s,回流区流速分布范围为0.09~0.25 m/s,流速大小在鱼类的克流能力范围之内,但靠竖缝隔板处存在明显的主流贴壁现象。为此开展了池室优化方案设计,使鱼道池室流态满足鱼类上溯要求。     

The GNAQ T96S Mutation Affects Cell Signaling and Enhances the Oncogenic Properties of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), the most common malignant tumor in the liver, grows and metastasizes rapidly. Despite advances in treatment modalities, the five-year survival rate of HCC remains less than 30%. We sought genetic mutations that may affect the oncogenic properties of HCC, using The Cancer Genome Atlas (TCGA) data analysis. We found that the GNAQ T96S mutation (threonine 96 to serine alteration of the Gαq protein) was present in 12 out of 373 HCC patients (3.2%). To examine the effect of the GNAQ T96S mutation on HCC, we transfected the SK-Hep-1 cell line with the wild-type or the mutant GNAQ T96S expression vector. Transfection with the wild-type GNAQ expression vector enhanced anchorage-independent growth, migration, and the MAPK pathways in the SK-Hep-1 cells compared to control vector transfection. Moreover, cell proliferation, anchorage-independent growth, migration, and the MAPK pathways were further enhanced in the SK-Hep-1 cells transfected with the GNAQ T96S expression vector compared to the wild-type GNAQ-transfected cells. In silico structural analysis shows that the substitution of the GNAQ amino acid threonine 96 with a serine may destabilize the interaction between the regulator of G protein signaling (RGS) protein and GNAQ. This may reduce the inhibitory effect of RGS on GNAQ signaling, enhancing the GNAQ signaling pathway. Single nucleotide polymorphism (SNP) genotyping analysis for Korean HCC patients shows that the GNAQ T96S mutation was found in only one of the 456 patients (0.22%). Our data suggest that the GNAQ T96S hotspot mutation may play an oncogenic role in HCC by potentiating the GNAQ signal transduction pathway.