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731.
V. Larionov N. Kouprina M. Eldarov E. Perkins G. Porter M. A. Resnick 《Yeast (Chichester, England)》1994,10(1):93-104
Rearrangements within plasmid DNA are commonly observed during transformation of eukaryotic cells. One possible cause of rearrangements may be recombination between repeated sequences induced by some lesions in the plasmid. We have examined the mechanisms of transformation-associated recombination in the yeast Saccharomyces cerevisiae using a plasmid system which allowed the effects of physical state and/or extent of homology on recombination to be studied. The plasmids contain homologous or diverged (19%) repeats of the URA3 genes (from S. cerevisiae or S. carlsbergensis) separated by the genetically detectable ADE2 colour marker. Recombination during transformation for covalently closed circular plasmids was over 100-fold more frequent than during mitotic growth. The frequency of recombination is partly dependent on the method of transformation in that procedures involving lithium acetate or spheroplasting yield higher frequencies than electroporation. When present in the repeats, unique single-strand breaks that are ligatable, as well as double-strand breaks, lead to high levels of recombination between diverged and identical repeats. The transformation-associated recombination between repeat DNAs is under the influence of the RAD52 and RAD1 genes. 相似文献
732.
Dinabandhu Bhandari Nikhil R. Pal D. Dutta Majumder 《Pattern recognition letters》1992,13(12):857-867
A new measure called divergence between two fuzzy sets is introduced along with a few properties. Its application to clustering problems is indicated and applied to an object extraction problem. A tailored version of the probability measure of a fuzzy event is also used for image segmentation. Both parametric and non-parametric probability distributions are considered in this regard. 相似文献
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734.
Predicting the number of accidents at a road junction 总被引:1,自引:1,他引:0
We consider a model, within a Bayesian framework, which can be used to predict the number of accidents occurring at a road
junction in a given period of time. The predictions are based on measurements of the traffic flows as well as on covariates
which describe important features of the junctions. Various approximate and estimative methods, which use Gibbs sampling,
posterior normality and Laplace approximations, are considered and compared. Procedures to assess the importance of the different
covariates through the use of the Kullback-Leibler measure of divergence are also developed. 相似文献
735.
运用光楔对发散角较大、光束品质不够好的KrF激光光束进行了分光测量,测量了KrF激光光束的一维能量分布和远场发散角;具体计算了KrF激光光束剖面的能量密度分布的均匀性。 相似文献
736.
737.
孙志和 《青岛理工大学学报》1995,(3)
针对菲赫金哥尔茨著《微积分学教程》第二卷第二分册中Riemann定理证明中的“注”(第314页)所提及条件收敛级数重排后发散的情形,分三种情形给予推证. 相似文献
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740.
The problem of building a regression tree is considered when the response variable is a probability density function. Splitting criteria which are well adapted to measure the dissimilarity between densities are proposed using the Csiszár's f-divergence. The comparison between performances of trees constructed with various criteria is tackled through numerical simulations. Afterwards, a tree is constructed to predict the size distribution of a zooplankton community using a set of explanatory environmental variables. Functional PCA is used in order to interpret the main modes of variation of the size spectra around the predicted density in each terminal node. Finally, a bagging procedure is used to increase the accuracy of the tree-based model. 相似文献