利用铽与钙调素的荧光熄灭作用测定精锌中镉

研究了Cd2+对铽离子与钙调素(CaM)所形成的配合物(Tb43+.CaM)的荧光熄灭作用,考察了常见金属离子的干扰情况,在pH=5.0的六次亚甲基四胺缓冲溶液中,不断通入N2作保护气体可防止O2对Tb43+.CaM荧光的熄灭作用。由此建立了测定Cd2+的新方法,Cd2+浓度在0.0723~15.80μg/mL范围内与荧光熄灭值ΔIF具有良好的线性关系,检测下限为0.044μg/mL,相对标准偏差为5.1%。用该方法测定了精锌中镉的含量,平均回收率为96.1%。     

铽的光度分析进展

综合介绍了近10a来测定铽的荧光法的研究状况，指出应加强其它铽的分析方法的研究及新荧光试剂的合成研究。     

臭氧在2-硝基-4-甲砜基苯甲酸合成中的作用

研究了臭氧在2-硝基4-甲砜基甲苯的氧化过程中的作用。以2-硝基-4-甲砜基甲苯为原料氧化制备2-硝基4-甲砜基苯甲酸的过程，分别使用硝酸、五氧化二钒和臭氧等多种氧化剂．通过比较这三种氧化剂单独使用和混合使用的效果，分析臭氧在该有机物的氧化中所起的作用．为臭氧合理使用提供依据。     

The influence of small hydrogen addition on the structural and magnetocaloric properties of high-purity nanocrystalline terbium

Hydrogen absorption often induces changes of various properties of rare-earth metals. In this paper, we study the influence of hydrogenation on the structural, magnetic and magnetocaloric properties of high-purity nanocrystalline terbium. Strong (00l) texture present in the parent Tb sample is practically destroyed after the hydrogenation procedure. We observe formation of agglomerates of different sizes and shapes depending on the hydrogen content in the samples. We find traces of β-hydride (TbH₂) in the main α-hydride TbH_x phase. For TbH_x with x = 0.25 and 0.5 at.H/f.u. The effect of hydrogenation on the magnetocaloric properties is studied in magnetic fields up to 9 T. The magnetocaloric effect decreases after hydrogenation. The -ΔS_M(T) curves feature a table-like effect in the vicinity of the magnetic phase transitions in magnetic fields exceeding 1 T.     

Modulation of Cyclins,p53 and Mitogen-Activated Protein Kinases Signaling in Breast Cancer Cell Lines by 4-(3,4,5-Trimethoxyphenoxy)benzoic Acid

Despite the advances in cancer therapy and early detection, breast cancer remains a leading cause of cancer-related deaths among females worldwide. The aim of the current study was to investigate the antitumor activity of a novel compound, 4-(3,4,5-trimethoxyphenoxy)benzoic acid (TMPBA) and its mechanism of action, in breast cancer. Results indicated the relatively high sensitivity of human breast cancer cell-7 and MDA-468 cells towards TMPBA with IC₅₀ values of 5.9 and 7.9 μM, respectively compared to hepatocarcinoma cell line Huh-7, hepatocarcinoma cell line HepG2, and cervical cancer cell line Hela cells. Mechanistically, TMPBA induced apoptotic cell death in MCF-7 cells as indicated by 4′,6-diamidino-2-phenylindole (DAPI) nuclear staining, cell cycle analysis and the activation of caspase-3. Western blot analysis revealed the ability of TMPBA to target pathways mediated by mitogen-activated protein (MAP) kinases, 5′ adenosine monophosphate-activated protein kinase (AMPK), and p53, of which the concerted action underlined its antitumor efficacy. In addition, TMPBA induced alteration of cyclin proteins’ expression and consequently modulated the cell cycle. Taken together, the current study underscores evidence that TMPBA induces apoptosis in breast cancer cells via the modulation of cyclins and p53 expression as well as the modulation of AMPK and mitogen-activated protein kinases (MAPK) signaling. These findings support TMPBA’s clinical promise as a potential candidate for breast cancer therapy.     

微波相转移催化快速合成苯甲酸

在相转移催化剂存在下 ,使用微波辐射快速合成了苯甲酸。该方法反应条件温和、操作简便 ,反应 1 5 min产率可达 85 % ,后处理不用脱色和重结晶就能得到白色的苯甲酸晶体。     

萃取色层分离测定钐铕钆富集物中的钐铕钆铽

研究了在P_(507)-HCl-(NH_4)_2SO_4体系中用萃取色层法定量分离钕、钐、铕、钆、铽和镝的条件,实验表明当用0.42mol/L HCl-0.5mol/L(NH_4)_2SO_4作淋洗剂时,上述元素都能定量分离。方法能用于钐、铕、钆富集物中钐、铕、钆和铽的测定。     

PTFE中空纤维膜萃取苯甲酸工艺研究

以氢氧化钠溶液为萃取剂,采用PTFE中空纤维膜萃取料液中的苯甲酸,考察了料液相苯甲酸的初始浓度、料液相初始pH、料液相与萃取相流量比、萃取剂的初始浓度对苯甲酸萃取率(η)的影响。结果表明,随着料液初始浓度增大,η增大,当苯甲酸浓度1 g/L时,η减小,但膜通量基本不变,即存在一个最大膜通量,此时苯甲酸浓度变化对传质无影响;料液的pH值下降,η增大;萃取相氢氧化钠浓度增大,η增大;存在一个最佳相流量比(Q料/Q萃)为1.8。另外,温度升高有利于膜萃取。     

两种高效低成本咪唑啉类缓蚀剂的研制

为了缓解油田设备因腐蚀引起的问题,实验通过有机合成方法,用苯甲酸(油酸)和三乙烯四胺及氯化苄合成得到咪唑啉季铵盐缓蚀剂,经过油酸咪唑啉季铵盐缓蚀剂与苯甲酸咪唑啉季铵盐缓蚀剂的复配后,通过静态失重法进行评价。结果表明这类缓蚀剂的最佳加药浓度为30 mg·L-1,此时两种酸类咪唑啉季铵盐含量比为2∶3时的缓蚀效率可以达到97.4%;主剂(苯甲酸∶油酸=2∶3)与硫脲、乌洛托品、乙酰苯胺按比例10∶5∶2∶1复配缓蚀效率可以达到98.4%,符合油田生产需求。