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991.
Core–shell type nanoparticles of poly(L ‐lactide)/poly(ethylene glycol) (LE) diblock copolymer were prepared by a dialysis technique. Their size was confirmed as 40–70 nm using photon correlation spectroscopy. The 1H‐NMR analysis confirmed the formation of core–shell type nanoparticles and drug loading. The particle size, drug loading, and drug release rate of the LE nanoparticles were slightly changed by the initial solvents that were used. The drug release behavior of LE core–shell type nanoparticles showed an initial burst during the first 12 h and then a sustained release until 100 h. The degradation behavior of LE block copolymer nanoparticles was divided into three phases: the initial rapid degradation phase, the stationary phase, and the rapid degradation phase until complete degradation. It was suggested that lidocaine release kinetics were predominantly governed by the diffusion mechanism in the initial burst phase and after that by both of the diffusion and degradation mechanisms. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 2625–2634, 2002 相似文献
992.
In recent years, three‐dimensionally (3D) braided composites have attracted a great deal of attention because of their high‐impact damage tolerance and fatigue life, superior fracture toughness, and so forth, and have been used in aeronautics, military, and transportation. These advantages make them strong candidates for osteosynthesis devices. In this study, 3D braided carbon fiber–epoxy (C3D/EP) composites were produced via a simple vacuum impregnation technique. The load‐deflection curve, mechanical properties, and influence of fiber volume fraction, braiding angle, and axial reinforcing fibers were examined to determine their suitability for internal fixation devices. It is found that the C3D/EP composites have excellent toughness and do not show brittleness when fractured because of their relatively high void content. The flexural, shear, and impact strengths of the C3D/EP composites are excellent. It was shown that a C3D/EP composite with a stiffness similar to load‐bearing bones can be made while maintaining enough strength. It is concluded that a relatively higher void content and braiding angle is more suitable for the C3D/EP composites from the viewpoint of requirements of fracture fixation materials. The moisture absorption behavior and changes in mechanical properties caused by moisture uptake were evaluated. Results show that absorbed moisture slightly decreases mechanical properties of the C3D/EP composites. Contrary to the unreinforced epoxy, the moisture absorption behavior of the C3D/EP composites cannot be described with Fick's law of diffusion, probably because of the presence of voids and/or 3D fiber structure. The exact mechanisms should be proposed in further investigations. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 85: 1031–1039, 2002 相似文献
993.
将具有完全晶格匹配势垒增强层的MSM-PD简化为一维模型,并通过理论分析,得出了它的暗电流特性,进一步得到器件暗电流与势垒增强层的关系。 相似文献
994.
995.
In this work we present a snake based approach for the segmentation of images of computerized tomography (CT) scans. We introduce a new term for the internal energy and another one for external energy which solve common problems associated with classical snakes in this type of images. A simplified minimizing method is also presented. 相似文献
996.
SDH中泊松分布下误块率与误码率的关系分析 总被引:2,自引:0,他引:2
本文较详细地介绍了SDH中的BIP误码校验方式,推导了泊松分布下,BIP误块率与误码率的一般关系式,给出了SDH中几种典型的误块率与误码率的关系曲线,并做了计算机模拟验证 相似文献
997.
城市中心区游憩功能的开发——以武汉市为例 总被引:6,自引:0,他引:6
张翰卿 《武汉大学学报(工学版)》2002,35(5):58-62
从我国游憩空间建设实践中 ,概括出对城市游憩功能认识过程的四个阶段 .进而 ,从城市中心商业区、历史街区和城市滨水区三个方面讨论了城市中心区的游憩功能开发问题 .最后 ,以武汉市为例进行了分析 相似文献
998.
Al(OH)3对硅橡胶性能的影响 总被引:1,自引:0,他引:1
综述了Al(OH)3粒径和用量对硅椽胶漏电电流、脉冲电流、耐漏电起痕、表面粗糙程度、电蚀损、介电性能、拉伸强度及漏电电流实验重复性的影响。 相似文献
999.
Monocrystalline 6H-SiC thin films have been epitaxially grown on off-axis 6H-SiC {0001} substrates in the temperature range
of 1623–1873 K via chemical vapor deposition. The growth rate was a strong function of the growth temperature and the reactant
gas concentration. The activation energies for growth were 64 kJ/mole and 55 kJ/mole for the (0001) Si face and the (0001)
C face, respectively. The concentration of growth pits in the films increased as a function of decreasing deposition temperature,
increasing concentration of reactant gases and increasing off-axis orientation. Beta-SiC islands were also observed in the
epilayers when the (SiH4 + C2H4)/H2 ratio was ≥2.5:3000. 相似文献
1000.
ßBarrels are widespread and well-studied featuresof a great many protein structures. In this paper an unsuper-visedmethod for the detection of P-barrels is developed based ontechniques from graph theory. The hydrogen bonded connectivityof ß-sheets is derived using standard pattern recognitiontechniques and expressed as a graph. Barrels correspond to topologicalrings in these connectivity graphs and can thus be identifiedusing ring perception algorithms. Following from this, the characteristictopological structure of a barrel can be expressed using a novelform of reduced nomenclature that counts sequence separationsbetween successive members of the ring set These techniquesare tested by applying them to the detection of barrels in anon-redundant subset of the Brookhaven database. Results indicatethat topological rings do seem to correspond uniquely to ß-barrelsand that the technique, as implemented, finds the majority ofbarrels present in the dataset. 相似文献