Requirements engineering in health care: the example of chemotherapy planning in paediatric oncology

Health care is characterized by highly complex processes of patient care that require unusual amount of communication between different health care professionals of different institutions. Sub-optimal processes can significantly impact on the patient’s health, increase the consumption of services and resources and in severe cases can lead to the patient death. For these reasons, requirements engineering for the development of information technology in health care is a complex process as well: without constant and rigorous evaluation, the impact of new systems on the quality of care is unknown and it is possible that badly designed systems significantly harm patients. To overcome these limitations, we present and discuss an approach to requirements engineering that we applied for the development of applications for chemotherapy planning in paediatric oncology. Chemotherapy planning in paediatric oncology is complex and time-consuming and errors must be avoided by all means. In the multi-hospital/multi-trial-centre environment of paediatric oncology, it is especially difficult and time-consuming to analyse requirements. Our approach combines a grounded theory approach with evolutionary prototyping based on the constant development and refinement of a generic domain model, in this case a domain model for chemotherapy planning in paediatric oncology. The prototypes were introduced in medical centres and final results show that the developed generic domain model is adequate.     

Study on the Complexity of the Bullwhip Effect

Recent years have witnessed a rapid growth of interest in the study of the dynamic behavior of replenishment rules of bullwhip effect. We prove that bullwhip effect and butterfly effect share a same the self-oscillation amplifying mechanism that is the ordering decisions the supplier self-oscillation amplify the perturbations brought by the errors in the processing of retailers' demand information. This results as an explicit self-similar structure of the sensitivity of the system to the initial values duty to the nonlinear mechanism. In this paper, the causes process of the bullwhip effect is described as the internal nonlinear mechanism and study on the complexity of bullwhip effect for order-up-to policy under demand signal processing. The methodology is based on fractal and chaotic theory and allows important insights to be gained about the complexity behavior of bullwhip effect.     

Review of Alterations of Consciousness: An Empirical Analysis for Social Scientists.

Reviews the book by Baruss (see record 2003-02669-000), which reviews the experimental and phenomenological research on alterations of consciousness, ranging from sleep and dreaming to mystical and near-death experience. The reviewer suggests there is a clear agenda announced by the book's subtitle, "An Empirical Analysis for Social Scientists." In the view of Baruss, all too often in states of consciousness research a preoccupation with theory has kept investigators from full engagement with the actual data. The book provides readable and at times appropriately controversial discussions of empirical literature on dreaming and lucid dreams, daydreaming and fantasy proneness, hypnosis, dissociative identity disorder, shamanism and possession states, psychedelic drug research, parapsychology, trance-chanelling and mediumship, the alien abduction syndrome, classical mystical experience, out-of-body and near-death experiences, and recent attempts by MacDonald and others to assess individual differences in spirituality through multifactor questionnaires. However, the reviewer believes that the breadth of coverage of both recent and past research is too often highly selective, and that the author's rejection of theory is both questionable in itself and more illusion than reality. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

火工品压药机装配误差的研究

针对军用雷管生产线中压药机结构,分别用极值法和概率法对压药机冲子和雷管的配合精度,进行了装配尺寸链的描述和计算,并对所得的结果进行了比较。     

Kinetics of two-step anionic polymerization

This article deals with the kinetics of two-step anionic polymerization by way of a non-steady state method. Several molecular parameters can be evaluated using the formulae developed. A bimodal molecular weight distribution function for the resulting polymer is derived from the set of kinetic differential equations, which is in agreement with the experimental data reported.     

控制理论的现状及对它的期望

本文首先简述了控制理论的发展过程，侧重叙述促进现代控制理论发展的主要因素，然后叙述了控制理论主要研究方向的进展及有待解决的问题，最后从第十二届ＩＦＡＣ世界大会看人们如何对待控制理论的各个方面。     

基于信息的智能控制理论研究

本文介绍的基于信息的智能控制理论的发展过程，主要分为智能控制的信息指标和智能控制的信息结构分析两部分，文中在最后对这套理论可能的发展方向进行了探讨。     

Quantitative feedback theory with applications in welding

Two different control systems were developed using quantitative feedback theory for weld quality improvement. The first application to be discussed was designed for the resistance pinch welding process and uses electrode displacement and force as feedback parameters. A correlation between weld quality and electrode displacement is established for constant electrode force. The system is capable of producing repeatable welds of consistent quality, with wide variations in weld parameters. This is the first time feedback control has been successfully applied to pinch welding. The second example presented in this paper was developed for penetration control of the gas-tungsten-arc welding process. The feedback signal is obtained by measuring the amount of light emitted from the back side of the weld. Welds of constant penetration have been demonstrated in tests with travel speeds varying from 1.5 to 6 inches per minute and with 200 per cent changes in part thickness.     

Design of minimax robust LQG controllers under parameter and noise uncertainties

The problem of design of minimax robust LQG controllers for linear systems with parameter and noise uncertainties is considered in this paper. Necessary and sufficient conditions for converting this problem to a two-person, zero-sum continuous game problem are presented. A simple procedure for design of a suboptimal minimax robust LQG controller, i.e., the LQG controller for least-favourable model, is proposed. Necessary and sufficient conditions for the existence of a saddle point are established. Under these conditions, the controller obtained is exactly the minimax LQG controller. When there does not exist a saddle point, the worst-case error between the controller obtained and the minimax robust LQG controllers under described uncertainties is bounded.     

不等波纹函数低通原型的理论及应用

本文提出不等波纹函数低通原型，并对其理论进行初步探讨。切比雪夫函数及最平坦型巴特活兹函数皆为其特例。文中给出不等波纹函数的几个性质，最后给出两个应用实例，消除耦合环自感部分的影响；抑制高次模的微带圆盘腔带通滤波器。