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61.
Water Resources Management - The localization of the leaks is estimated using the time difference method in the past decade. Generalized and Basic Cross-correlation techniques are frequently...  相似文献   
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Wireless Personal Communications - Education-as-a-Service is the new proposition of this paper, which intelligence mapped with extracted knowledge from the educational data with the sole objective...  相似文献   
64.
The deubiquitinase (DUB) ubiquitin C-terminal hydrolase L1 (UCHL1) is expressed primarily in the central nervous system under normal physiological conditions. However, UCHL1 is overexpressed in various aggressive forms of cancer with strong evidence supporting UCHL1 as an oncogene in lung, glioma, and blood cancers. In particular, the level of UCHL1 expression in these cancers correlates with increased invasiveness and metastatic behavior, as well as poor patient prognosis. Although UCHL1 is considered an oncogene with potential as a therapeutic target, there remains a significant lack of useful small-molecule probes to pharmacologically validate in vivo targeting of the enzyme. Herein, we describe the characterization of a new covalent cyanopyrrolidine-based UCHL1 inhibitory scaffold in biochemical and cellular studies to better understand the utility of this inhibitor in elucidating the role of UCHL1 in cancer biology.  相似文献   
65.
Wireless Personal Communications - In the era of cloud computing, any mobile device can augment its capabilities by using Cloud computation service. There are different services provided by...  相似文献   
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In the generation of electricity and cogeneration, Kalina cycle is considered as one of the competitors to organic Rankine cycle. With the simplicity and identical components of the binary mixture, Kalina system makes it more prominent to get developed and implemented as well with its environmental friendly associate. This work proposes a new improved Kalina cycle system to convert the natural source from sun to useful work. The proposed system utilizes heat source suitable to medium temperature heat applications. The proposed cycle have 2 units of solar collector, favoring an additional heat recovery and higher performance. Solar hot source temperature and pressure are 190°C and 45 bar with additional flow to the turbine of 1.15 kg/s. Energy and second law analysis have considered in evaluating the performance of the proposed plant. The energy analysis shows minimum value of net power, energy efficiency and plant efficiency as 241 kW, 15.5% and 5.7. The exergy analysis defines that, to the proposed cycle, the exergy efficiency initializes at 77% with more exergy destruction at turbine with 31%. With the parametric analysis, the system is amended to have the maximum values of energy and exergy performances as 18.5%, 7.1% and 85%. The parametric study identifies the optimum value of the inlet temperature and pressure of the pump and turbine.  相似文献   
68.
The influence of austenitization and austempering parameters on the impact properties of copper-alloyed and nickel-copper-alloyed austempered ductile irons (ADIs) has been studied. The austenitization temperature of 850 and 900 °C have been used in the present study for which austempering time periods of 120 and 60 min were optimized in an earlier work. The austempering process was carried out for 60 min for three austempering temperatures of 270, 330, and 380 °C to study the effect of austempering temperature. The influence of the austempering time on impact properties has been studied for austempering temperature of 330 °C for time periods of 30-150 min. The variation in impact strength with the austenitization and austempering parameters has been correlated to the morphology, size and amount of austenite and bainitic ferrite in the austempered structure. The fracture surface of ADI failed under impact has been studied using SEM.  相似文献   
69.
Air pollution is one of the major concerns considering detriments to human health. This type of pollution leads to several health problems for humans, such as asthma, heart issues, skin diseases, bronchitis, lung cancer, and throat and eye infections. Air pollution also poses serious issues to the planet. Pollution from the vehicle industry is the cause of greenhouse effect and CO2 emissions. Thus, real-time monitoring of air pollution in these areas will help local authorities to analyze the current situation of the city and take necessary actions. The monitoring process has become efficient and dynamic with the advancement of the Internet of things and wireless sensor networks. Localization is the main issue in WSNs; if the sensor node location is unknown, then coverage and power and routing are not optimal. This study concentrates on localization-based air pollution prediction systems for real-time monitoring of smart cities. These systems comprise two phases considering the prediction as heavy or light traffic area using the Gaussian support vector machine algorithm based on the air pollutants, such as PM2.5 particulate matter, PM10, nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3), and sulfur dioxide (SO2). The sensor nodes are localized on the basis of the predicted area using the meta-heuristic algorithms called fast correlation-based elephant herding optimization. The dataset is divided into training and testing parts based on 10 cross-validations. The evaluation on predicting the air pollutant for localization is performed with the training dataset. Mean error prediction in localizing nodes is 9.83 which is lesser than existing solutions and accuracy is 95%.  相似文献   
70.
Wireless Personal Communications - Alzheimer’s Disease is a degenerative neurological disease that progresses slowly and gradually. Currently incurable, and those who suffer from it deprive...  相似文献   
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