Twin screw granulation – review of current progress

Twin screw granulation (TSG) is a new process of interest to the pharmaceutical community that can continuously wet granulate powders, doing so at lower liquid concentrations and with better product consistency than found by a high shear batch mixer. A considerable body of research has evolved over the short time since this process was introduced but generally with little comparison of results. A certain degree of confidence has been developed through these studies related to how process variables and many attributes of machinery configuration will affect granulation but some major challenges still lay ahead related to scalability, variations in the processing regimes related to degree of channel fill and the impact of wetting and granulation of complex powder formulations. This review examines the current literature for wet granulation processes studied in twin screw extrusion machinery, summarizing the influences of operational and system parameters affecting granule properties as well as strives to provide some practical observations to newly interested users of the technique.     

提高托盘利用效率的重要手段——电子信息化管理

托盘能否有效运用对物流的畅通与否关系重大,这已经引起了国内外专家和学者们的重视,并就此制定了托盘电子信息化管理系统,旨在更合理地使用托盘,推进托盘一体化和共用系统的建立。而RFID技术在托盘的电子信息化管理的应用更将大大提高物流的效率与准确性,托盘电子信息化管理将成为今后托盘管理的趋势。     

薄板坯连铸工艺液芯压下的有限元分析

简要介绍世界几种主要薄板坯连铸工艺。着重叙述应用大型通用商业软件MSC.MARC。模拟液芯压下时铸坯的变形，确定最佳压下方案的有限元分析，液芯压下应该在结晶器出口处及二冷区扇形段开始部分进行，这样能减小铸坯的应变。     

Fast determination of critical eluent composition for polymers by gradient chromatography

Gradient chromatography was applied in order to calculate the composition at elution for different methacrylates on normal phase columns. In addition the composition at elution was determined for polyethyleneoxide on a reverse phase column. It is shown that high molar mass polymers elute for a given homopolymer irrespective of their molar mass at the same eluent composition, which varies only slightly with gradient slope. In general the composition at elution in gradient chromatography is expected to be slightly lower than the true critical composition. For high molar mass polymers we found this composition to be close to the critical composition determined by isocratic experiments. The difference between the composition at elution and the true critical composition for a variety of polymethacrylates and for polyethyleneglycol was found to be only between 0.2 and 5%. Thus, after estimating the composition at elution, only a small number of additional isocratic experiments is needed to find the exact critical composition.     

Structural and Superconducting Property Variations with Nominal Mg Non‐Stoichiometry in MgxB2 and Its Enhancement of Upper Critical Field

By applying a combination of characterisation tools, changes in structural and superconducting properties with nominal Mg non‐stoichiometry in Mg_xB₂ are found. The non‐stoichiometry produces enhanced in‐field critical current densities (J_c's) and upper critical field / irreversibility field (H_c2/H_irr(T)) values. Upper critical fields of ～ 21 T (4.2 K) were obtained in nominal Mg‐deficient samples compared to ～ 17 T (4.2 K) for near‐stoichiometric samples.     

Critical heat flux on a flat plate heater located at the middle of a duct in forced flow of pressurized He II

Critical heat fluxes (CHFs) were measured for two types of rectangular ducts containing horizontal flat plate heaters. One has the flat plate heater of 6 mm wide and 20 mm long located on the inner lower wall at 50 mm from the inlet. The other duct has two horizontal flat plates of 6 mm wide and 20 mm long on inner upper and lower walls at 50 mm from the inlet. The equation of CHF for the forced convection containing a new nondimensional-parameter m introduced in order to calculate cross-sectionally averaged liquid temperature at the center of the duct was derived based on two fluid model, ordinary convection theorem and experimental results. It was confirmed that this correlation can describe not only the author's data on the duct but also other worker's data for channels with different shapes and sizes.     

糖厂现用连续离心机的研究及生产实践

在各糖厂现用连续离心机原有生产实践基础上，对其机械吸震、加温、布温、机索结构、物料密封、机座等部件做了进一步改进，并取得可观的实效。     

基于Native Mode ATM API的应用系统模型及关键技术

ＡＴＭ技术作为Ｂ－ＩＳＤ的基础，在传输包括话音、图像、数据的综合业务环境中具有现有其它网络技术所不具备的技术优势，然而目前真正基于ＡＴＭＮａｔｉｖｅＭｏｄｅ的应用还很少，而大量基于Ｏｖｅｒｌａｙ Ｍｏｄｅ的ＡＴＭ应用不能充分发挥ＡＴＭ技术的优势。随着信息技术的发展，将会有大量的综合业务应用出现，它具有和传统数据通信安全不同的业务特性，必须通过一种灵活，高效的应用程序接口给予支持，本文提出基于Ｎａｔ     

钻速模式动态辨识方法研究

目的：钻进过程是一个复杂的工艺过程，影响钻速的因素错综复杂。为钻井参数优化和实时控制，提出钻速动态模型。方法：对影响钻速的因素进行分析，用系统辨识方法建立钻速模式。结果：利用该方法建立了华北油田岔河集地区的钻速模型，取得满意结果。结论：此动态钻速模式能更准确、科学地描述钻进过程，并在钻井参数最优化、钻井过程的闭环控制等方面具有广阔的应用前景。