全文获取类型
收费全文 | 19435篇 |
免费 | 2366篇 |
国内免费 | 1628篇 |
专业分类
电工技术 | 2292篇 |
技术理论 | 1篇 |
综合类 | 1764篇 |
化学工业 | 1455篇 |
金属工艺 | 1390篇 |
机械仪表 | 1856篇 |
建筑科学 | 2719篇 |
矿业工程 | 1181篇 |
能源动力 | 581篇 |
轻工业 | 706篇 |
水利工程 | 782篇 |
石油天然气 | 1081篇 |
武器工业 | 287篇 |
无线电 | 1247篇 |
一般工业技术 | 2639篇 |
冶金工业 | 736篇 |
原子能技术 | 230篇 |
自动化技术 | 2482篇 |
出版年
2024年 | 36篇 |
2023年 | 279篇 |
2022年 | 537篇 |
2021年 | 775篇 |
2020年 | 745篇 |
2019年 | 654篇 |
2018年 | 494篇 |
2017年 | 649篇 |
2016年 | 695篇 |
2015年 | 840篇 |
2014年 | 1231篇 |
2013年 | 1315篇 |
2012年 | 1500篇 |
2011年 | 1618篇 |
2010年 | 1198篇 |
2009年 | 1254篇 |
2008年 | 1116篇 |
2007年 | 1247篇 |
2006年 | 1196篇 |
2005年 | 983篇 |
2004年 | 816篇 |
2003年 | 746篇 |
2002年 | 636篇 |
2001年 | 489篇 |
2000年 | 396篇 |
1999年 | 357篇 |
1998年 | 284篇 |
1997年 | 238篇 |
1996年 | 188篇 |
1995年 | 176篇 |
1994年 | 129篇 |
1993年 | 97篇 |
1992年 | 93篇 |
1991年 | 75篇 |
1990年 | 56篇 |
1989年 | 54篇 |
1988年 | 43篇 |
1987年 | 23篇 |
1986年 | 13篇 |
1985年 | 23篇 |
1984年 | 20篇 |
1983年 | 17篇 |
1982年 | 7篇 |
1981年 | 6篇 |
1980年 | 8篇 |
1979年 | 14篇 |
1961年 | 5篇 |
1960年 | 6篇 |
1959年 | 7篇 |
1955年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 140 毫秒
1.
Yarn-dyed fabric is often woven from warp and weft yarns in the same color depth to ensure a uniform color appearance. The difference in color depth between warp and weft tends to result in the uneven color of the yarn-dyed fabric. This article aims to establish a color tolerance for yarn-dyed fabric that can be woven with a qualified color appearance but from the warp and weft yarns in different color depths. A total of 27 yarn-dyed fabric samples in three color series (red, yellow, and blue) were evaluated by using the yarn-dyed fabric from warp and weft yarns in the same color depth of 2% (on weight of fabric, owf) as the standard. Visual assessment and instrumental measurement of color were carried out to establish the color tolerance ellipse that was defined as CMC (Color Measurement Committee) color differences (2:1) of no more than 1.00. It was found that the color strengths (K/S) and color differences (ΔECMC(2:1)) of these fabric samples for each color series had linear relationships with the color depths of warp and weft yarns. The color tolerance ellipses indicated that, even though the warp and weft yarns had an apparent color difference, they could be woven in fabrics with relatively uniform color appearance and meet the requirements for yarn-dyed fabric. This work provided valuable insight into the production of qualified yarn-dyed fabrics from unqualified dyed yarns. 相似文献
2.
3.
Cho-Yi Chen Masaoki Kawasumi Tien-Yun Lan Chi-Lam Poon Yi-Sian Lin Pin-Jou Wu Yao-Chung Chen Bing-Hong Chen Cheng-Hsien Wu Jeng-Fan Lo Rueyhung Roc Weng Yi-Chen Sun Kai-Feng Hung 《International journal of molecular sciences》2021,22(1)
Endoplasmic reticulum (ER) stress response is an adaptive program to cope with cellular stress that disturbs the function and homeostasis of ER, which commonly occurs during cancer progression to late stage. Late-stage cancers, mostly requiring chemotherapy, often develop treatment resistance. Chemoresistance has been linked to ER stress response; however, most of the evidence has come from studies that correlate the expression of stress markers with poor prognosis or demonstrate proapoptosis by the knockdown of stress-responsive genes. Since ER stress in cancers usually persists and is essentially not induced by genetic manipulations, we used low doses of ER stress inducers at levels that allowed cell adaptation to occur in order to investigate the effect of stress response on chemoresistance. We found that prolonged tolerable ER stress promotes mesenchymal–epithelial transition, slows cell-cycle progression, and delays the S-phase exit. Consequently, cisplatin-induced apoptosis was significantly decreased in stress-adapted cells, implying their acquisition of cisplatin resistance. Molecularly, we found that proliferating cell nuclear antigen (PCNA) ubiquitination and the expression of polymerase η, the main polymerase responsible for translesion synthesis across cisplatin-DNA damage, were up-regulated in ER stress-adaptive cells, and their enhanced cisplatin resistance was abrogated by the knockout of polymerase η. We also found that a fraction of p53 in stress-adapted cells was translocated to the nucleus, and that these cells exhibited a significant decline in the level of cisplatin-DNA damage. Consistently, we showed that the nuclear p53 coincided with strong positivity of glucose-related protein 78 (GRP78) on immunostaining of clinical biopsies, and the cisplatin-based chemotherapy was less effective for patients with high levels of ER stress. Taken together, this study uncovers that adaptation to ER stress enhances DNA repair and damage tolerance, with which stressed cells gain resistance to chemotherapeutics. 相似文献
4.
5.
6.
Coline Grisotto Janice Taïl Cynthia Planesse Nicolas Diotel Marie-Paule Gonthier Olivier Meilhac David Couret 《International journal of molecular sciences》2021,22(9)
Background: Stroke in context of type 2 diabetes (T2D) is associated with a poorer outcome than in non-diabetic conditions. We aimed at creating a new reproducible mouse model of stroke in impaired glucose tolerance conditions induced by high-fat diet. Methods: Adult C57BL6 mice were fed for 2 months with either normal diet (ND) or high-fat diet (HFD). We used a model of Middle Cerebral Artery Occlusion (MCAO) for 90 min. Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT) were used to assess pre-diabetic status. Brain infarct volume, hemorrhagic transformation (HT) as well as systemic and cerebral inflammatory markers were evaluated. Results: HFD was associated with an increased body weight and glycemia following OGTT. The HFD group presented a significant increase in brain infarct volume (38.7 (IQR 30–46.7%) vs. 28.45 (IQR 21–30%); p = 0.016) and HT (HFD: 2 (IQR 1–5) vs. ND: 0 (IQR 0–1); p = 0.012) and higher levels of IL-6 and MCP-1 in infarcted hemisphere compared to the ND group. Conclusion: Two months of HFD in adult mice were sufficient to alter the lipid profile and the control of hyperglycemia. These metabolic perturbations were significantly associated with increased infarct volume and hemorrhagic complications. 相似文献
7.
《Ceramics International》2021,47(18):25769-25776
Lithium-sulfur battery cathodes still remain a challenge on capacity decay due to the shuttle effect even though a series of strategies have been tried. Here we report a novel matryoshka-like CuS@void@Co3O4 architecture of double micro-cubes (μ-cubes) that locks sulfur between the CuS core and the Co3O4 shell. Plenty of existing spaces between the μ-cubes suffice a high loading of sulfur and volumetric accommodation. The robust, double closed cubes configuration greatly enhances the confinement of polysulfides. In parallel, the CuS core increases the electronic conductivity and contributes to additional capacity, while the Co3O4 shell ensures a better interface activity. A high Li+ ion diffusion coefficient is obtained during the sulfur and lithium sulfide transformation. The constructed battery displays an initial capacity up to 1480 mAh g−1, and a Coulombic efficiency (CE) exceeding 99%. A capacity retention higher than 500 mAh g−1 with a CE larger than 99.8% after cycling 400 times at 0.2 C are achieved. In addition, under a temperature of −5 °C, a high capacity of 700 mAh g−1 at 0.2 C after 200 cycles is achieved, indicating a good low-temperature tolerance. 相似文献
8.
《Ceramics International》2022,48(17):24888-24897
In the furnace cycle test, the growth of oxide film leads to the propagation and coalescence of multiple cracks near the interface, which should be responsible for the spallation of thermal barrier coatings (TBCs). A TBC model with real interface morphology is created, and the near-interface large pore is retained. The purpose of this work is to clarify the mechanism of TBC spallation caused by successive initiation, propagation, and linkage of cracks near the interface during thermal cycle. The dynamic growth of thermally grown oxide (TGO) is carried out by applying a stress-free strain. The crack nucleation and arbitrary path propagation in YSZ and TGO are simulated by the extended finite element method (XFEM). The debonding along the YSZ/TGO/BC interface is evaluated using a surface-based cohesive behavior. The large-scale pore in YSZ near the interface can initiate a new crack. The ceramic crack can propagate to the YSZ/TGO interface, which will accelerate the interfacial damage and debonding. For the TGO/BC interface, the normal compressive stress and small shear stress at the valley hinder the further crack propagation. The growth of YSZ crack and the formation of through-TGO crack are the main causes of TBC delamination. The accelerated BC oxidation increases the lateral growth strain of TGO, which will promote crack propagation and coalescence. The optimization design proposed in this work can provide another option for developing TBC with high durability. 相似文献
9.
为探索镁合金整体壁板压弯成形的可行性,以及镁合金壁板压弯成形过程中金属的流动规律,对AZ31镁合金网格壁板压弯成形进行了数值模拟和实验研究。建立了有限元数值模拟的几何模型,采用有限元计算软件对AZ31镁合金网格壁板压弯成形过程进行了数值模拟研究,分析了镁合金网格壁板压弯成形中的温度场、应变场、应力场、破坏系数等的分布规律。确定了合适的AZ31镁合金壁板压弯成形工艺参数,并对镁合金网格壁板压弯成形进行了实验研究,获得了合格的镁合金网格壁板弯曲件,并分析了镁合金网格壁板成形件尺寸精度,模拟结果与实验结果相吻合,最大相对误差为16.7%。 相似文献
10.