用于电弧检测的电力专用SoC设计

针对传统的电弧电路故障检测结果不准确的问题,设计用于电弧检测的SoC系统,并且在55nm工艺下进行流片验证。采用包含两种结构的模数转换器的片上电压源,设计了锁相环以及复位电路,精度最高可达8.67 bit。验证结果表明,本设计可提高电弧检测的准确性。     

一种可控的自动扶梯电磁铁驱动电路板

扶梯制动系统是扶梯在出现紧急状况下确保乘客安全的重要设施。制动系统中的安全制动是在工作制动器无法在规定的时间内制停扶梯的一个措施,往往是在一些特别危险的场合下被触发,因此对于此制动器的控制显得尤为重要。本文提出了一种新型的自动扶梯制动器电磁铁驱动电路的设计,该设计用纯电子线路替代了传统的电气与电子组合形式,直接由自动扶梯单片机控制单元进行控制。     

Gaseous ozone to preserve quality and enhance microbial safety of fresh produce: Recent developments and research needs

Fresh fruits and vegetables are highly perishable and are subject to large postharvest losses due to physiological (senescence), pathologic (decay), and physical (mechanical damage) factors. In addition, contamination of fresh produce with foodborne human pathogens has become a concern. Gaseous ozone has multiple benefits including destruction of ethylene, inactivation of foodborne and spoilage microorganisms, and degradation of chemical residues. This article reviews the beneficial effects of gaseous ozone, its influence on quality and biochemical changes, foodborne human pathogens, and spoilage microorganisms, and discusses research needs with an emphasis on fruits. Ozone may induce synthesis of a number of antioxidants and bioactive compounds by activating secondary metabolisms involving a wide range of enzymes. Disparities exist in the literature regarding the impact of gaseous ozone on quality and physiological processes of fresh produce, such as weight loss, ascorbic acid, and fruit ripening. The disparities are complicated by incomplete reporting of the necessary information, such as relative humidity and temperatures at which ozone measurement and treatment were performed, which is needed for accurate comparison of results among studies. In order to fully realize the benefits of gaseous ozone, research is needed to evaluate the molecular mechanisms of gaseous ozone in inhibiting ripening, influence of relative humidity on the antimicrobial efficacy, interaction between ozone and the cuticle of fresh produce, ozone signaling pathways in the cells and tissues, and so forth. Possible adverse effects of gaseous ozone on quality of fresh produce also need to be carefully evaluated for the purpose of enhancing microbial and chemical safety of fresh produce.     

Mesenchymal Stromal Cell Therapy in Novel Porcine Model of Diffuse Liver Damage Induced by Repeated Biliary Obstruction

In liver surgery, biliary obstruction can lead to secondary biliary cirrhosis, a life-threatening disease with liver transplantation as the only curative treatment option. Mesenchymal stromal cells (MSC) have been shown to improve liver function in both acute and chronic liver disease models. This study evaluated the effect of allogenic MSC transplantation in a large animal model of repeated biliary obstruction followed by partial hepatectomy. MSC transplantation supported the growth of regenerated liver tissue after 14 days (MSC group, n = 10: from 1087 ± 108 (0 h) to 1243 ± 92 mL (14 days); control group, n = 11: from 1080 ± 95 (0 h) to 1100 ± 105 mL (14 days), p = 0.016), with a lower volume fraction of hepatocytes in regenerated liver tissue compared to resected liver tissue (59.5 ± 10.2% vs. 70.2 ± 5.6%, p < 0.05). Volume fraction of connective tissue, blood vessels and bile vessels in regenerated liver tissue, serum levels of liver enzymes (AST, ALT, ALP and GGT) and liver metabolites (albumin, bilirubin, urea and creatinine), as well as plasma levels of IL-6, IL-8, TNF-α and TGF-β, were not affected by MSC transplantation. In our novel, large animal (pig) model of repeated biliary obstruction followed by partial hepatectomy, MSC transplantation promoted growth of liver tissue without any effect on liver function. This study underscores the importance of translating results between small and large animal models as well as the careful translation of results from animal model into human medicine.     

Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field

Plant specialized metabolites (SMs) play an important role in the interaction with the environment and are part of the plant defense response. These natural products are volatile, semi-volatile and non-volatile compounds produced from common building blocks deriving from primary metabolic pathways and rapidly evolved to allow a better adaptation of plants to environmental cues. Specialized metabolites include terpenes, flavonoids, alkaloids, glucosinolates, tannins, resins, etc. that can be used as phytochemicals, food additives, flavoring agents and pharmaceutical compounds. This review will be focused on Mediterranean crop plants as a source of SMs, with a special attention on the strategies that can be used to modulate their production, including abiotic stresses, interaction with beneficial soil microorganisms and novel genetic approaches.     

Labeling and Characterization of Phenol-Containing Glycopeptides Using Chemoselective Probes with Isotope Tags

Secondary metabolites are structurally diverse natural products (NPs) and have been widely used for medical applications. Developing new tools to enrich NPs can be a promising solution to isolate novel NPs from the native and complex samples. Here, we developed native and deuterated chemoselective labeling probes to target phenol-containing glycopeptides by the ene-type labeling used in proteomic research. The clickable azido-linker was included for further biotin functionalization to facilitate the enrichment of labeled substrates. Afterward, our chemoselective method, in conjunction with LC-MS and MSn analysis, was demonstrated in bacterial cultures. A vancomycin-related phenol-containing glycopeptide was labeled and characterized by our labeling strategy, showing its potential in glycopeptide discovery in complex environments.     

Computer aided diagnosis of brain abnormalities using texture analysis of MRI images

The drive of this study is to develop a robust system. A method to classify brain magnetic resonance imaging (MRI) image into brain-related disease groups and tumor types has been proposed. The proposed method employed Gabor texture, statistical features, and support vector machine. Brain MRI images have been classified into normal, cerebrovascular, degenerative, inflammatory, and neoplastic. The proposed system has been trained on a complete dataset of Brain Atlas-Harvard Medical School. Further, to achieve robustness, a dataset developed locally has been used. Extraordinary results on different orientations, sequences of both of these datasets as per accuracy (up to 99.6%), sensitivity (up to 100%), specificity (up to 100%), precision (up to 100%), and AUC value (up to 1.0) have been achieved. The tumorous slices are further classified into primary or secondary tumor as well as their further types as glioma, sarcoma, meningioma, bronchogenic carcinoma, and adenocarcinoma, which could not be possible to determine without biopsy, otherwise.     

Study of planar structure applying reciprocity technique combined with MGEC and analysis of discontinuity

The 3D structure electromagnetic computation presents several difficulties related to the volume mesh. In fact, the entire volume space must be taken into account even the smallest details. In this article, we propose a formulation based on the reciprocity theorem combined with the generalized equivalent circuit method to model a planar 3D structure with both coaxial and planar excitation. The major advantage of this formulation is the fact to reduce the computational volume into 2D ones in the discontinuity plane. In addition, we focused on the calculation of the discontinuity between the excitation source and the planar structure to determine the exact behavior of the electric coaxial excitation model. The obtained current density, electric field distributions, and the input impedance are presented and discussed in the following sections. An approximately good agreement of input impedance with those obtained by the simulator and measurement is shown.     

QKD系统中基于EA电路的诱骗态实现

使用诱骗态量子秘钥方案可以解决因光子数分离攻击而导致的安全漏洞,保证了长距离量子通信的安全。本文介绍了量子通信的相关原理,通过对电吸收调制电路和激光器驱动电路的设计,精确控制产生了1550 nm波段的窄脉冲,经过内部调制成功制备诱骗态光脉冲,其强度约为信号态光脉冲的三分之一,因激光器的同一性而具有一致的光学特征从而避免了时频窃听,并具有强度可调的优点。