Relationship of cow and calf circulating lipidomes with colostrum lipid composition and metabolic status of the cow

Newborn calves rely on lipids in colostrum for energy and immune function. The lipid concentration in colostrum, however, is highly variable, and little is known about its composition and maternal factors that influence its composition. The first objective was to measure plasma lipid composition of multiparous cows at 35 d before calving (BC; 35 ± 3 d; ± standard deviation) and 7 d BC (7 ± 2 d), their colostrum, and serum lipid composition of calves (24 h after birth) using multiple reaction monitoring profiling, which is an exploratory and highly sensitive lipidomic analysis method that screens lipids based on chemical functionality. Second, data were analyzed to determine if there were relationships between circulating lipids in the cow, colostrum lipids, and calf serum lipids. Third, relationships between markers of metabolic status of the cows and circulating and colostrum lipids were analyzed with correlation analysis. Blood was sampled and plasma prepared from multiparous cows (n = 16) at 35 and 7 d BC. Within 3 h of parturition, colostrum was collected from cows and fed to her calf. Calves received another feeding of colostrum within 12 h after birth and a serum sample was collected from each calf 24 h after the first feeding of colostrum. The metabolic status of cows was evaluated using insulin, glucose, and nonesterified fatty acid area under the curve in response to an intravenous glucose tolerance test performed at 3 wk BC. Lipids were extracted from plasma, colostrum, and calf serum and were analyzed using multiple reaction monitoring profiling. Concentration of lipids were calculated using spiked in standards and expressed as percent of lipids identified. Data were uploaded into MetaboAnalyst 5.0 for multivariate and univariate analysis. Principal component analysis indicated that circulating lipids in the cow and calf were distinct from lipids in colostrum. Phosphatidylglycerol (PG) concentration was greater in colostrum and calf serum than in cow plasma, with 23 of the 24 PG found in colostrum also found in calf serum. In response to intravenous glucose tolerance test in late gestation, nonesterified fatty acid area under the curve was positively related to total triacylglycerols lipids in 7 d BC plasma (r = 0.63) but negatively related to total membrane lipids in colostrum (r = ?0.55). Thus, the metabolic status of the dam influences circulating lipids and colostrum lipid content. Moreover, the circulating lipidome of the cow and calf are similar to one another and distinct from the colostrum lipidome, except for PG, where it appears that colostrum serves as the source for PG in the calf's circulation.     

接触器触头系统振动机理分析及算法优化

为了解决合闸过程中动、静触头接触引起的振动弹跳问题.本文建立了接触系统的二自由度运动微分方程,并利用遗传算法对交流接触器吸合过程进行优化,同时通过高速摄影实验对接触弹跳的全过程进行了观察和分析.结果表明:理论与实验结果高度一致,铁心在触头分离前发生碰撞,进一步加剧触头弹跳;铁芯弹跳再次碰撞时,触头的弹跳不受影响;在接触器运行过程中,动铁芯的运动会引起系统轻微振动;采用遗传算法优化的接触器触头弹跳时间和最大振幅均减小.研究结果为进一步控制和减小接触弹跳提供了理论依据.     

雷达发射机浮动板调制器与故障检测电路的设计

提出了一种改进的浮动板调制器和对正负偏电压的故障检测电路,利用MOSFET寄生电容特性,通过固定脉宽窄脉冲控制调制脉宽,通过增加负偏MOSFET提高输出负偏电压。对故障检测电路进行仿真实验,通过模拟故障,验证故障检测报警信号发生时间均在微秒级别。完成样机的搭建,利用多重方式解决高压绝缘问题,并对其加电进行试验验证,分析实验波形,证明此电路满足设计要求并且具有可行性。     

氯碱企业快速熔断器运行状况调查报告

以2018年58家氯碱企业供电、整流技术与设备现状调查数据为依据,阐述了国内氯碱企业中快速熔断器的运行状况。调查数据中包括50家氯碱企业的快速熔断器的基本运行数据、投运时间及设备来源等。汇总了各企业在氯碱生产中使用快速熔断器时遇到的问题、发生的故障甚至酿成的生产事故及对氯碱生产造成的影响。并分析了事故发生的原因,提出了预防及解决措施,总结了事故处理经验,旨为氯碱生产提供参考依据。     

Compiler compatible 5.66 Mb/mm2 8T 1R1W register file in 14 nm FinFET technology

1-read/1-write (1R1W) register file (RF) is a popular memory configuration in modern feature rich SoCs requiring significant amount of embedded memory. A memory compiler is constructed using the 8T RF bitcell spanning a range of instances from 32 b to 72 Kb. An 8T low-leakage bitcell of 0.106 μm² is used in a 14 nm FinFET technology with a 70 nm contacted gate pitch for high-density (HD) two-port (TP) RF memory compiler which achieves 5.66 Mb/mm² array density for a 72 Kb array which is the highest reported density in 14 nm FinFET technology. The density improvement is achieved by using techniques such as leaf-cell optimization (eliminating transistors), better architectural planning, top level connectivity through leaf-cell abutment and minimizing the number of unique leaf-cells. These techniques are fully compatible with memory compiler usage over the required span. Leakage power is minimized by using power-switches without degrading the density mentioned above. Self-induced supply voltage collapse technique is applied for write and a four stack static keeper is used for read Vmin improvement. Fabricated test chips using 14 nm process have demonstrated 2.33 GHz performance at 1.1 V/25 °C operation. Overall V_min of 550 mV is achieved with this design at 25 °C. The inbuilt power-switch improves leakage power by 12x in simulation. Approximately 8% die area of a leading 14 nm SoC in commercialization is occupied by these compiled RF instances.     

我国MTBE的生产使用现状及趋势分析

对我国MTBE的生产工艺及下游产品进行了详细的分析,重点分析了影响MTBE产品生产使用的各方面因素,从能源方针、车用燃料政策及环保要求等角度对我国MTBE产品的未来发展趋势进行了预测分析。结果显示,2020年以后我国汽油调和用MTBE的生产使用量将逐步降低,但此过程可能会较为平缓。     

高温车用燃料电池的发展及现状综述

燃料电池车以其能量转化效率高、绿色环保、噪音低等优点，被认为是替代传统化石能源汽车最有前景的新能源汽车。目前车用燃料电池的工作温度一般都低于80℃，低温的工作环境使其面临着诸多问题，如复杂的水管理和CO中毒等。通过提高质子交换膜燃料电池（PEMFC）的工作温度可以缓解这些问题，提高燃料电池的性能。然而，高温的工作环境也会对燃料电池带来诸多挑战，如膜脱水、催化剂团聚、冷启动速度缓慢等。要促进高温（90～120℃）车用燃料电池的快速发展，需要对其问题及解决方法进行分析。本文从电堆比功率、膜电极、双极板、进气方式、加湿方式等方面，介绍燃料电池的发展现状及存在的问题，包括Nafion膜和催化剂的热稳定问题、双极板的耐腐蚀问题、流道的气体分配问题、进气方式和加湿方式的优化以及冷启动问题。指出通过掺杂亲水性氧化物改善Nafion膜的高温性能；将Pt合金化及采用介孔炭提高催化剂的稳定性和电化学活性；镀层不锈钢金属双极板可以增强耐腐蚀性；3D流场等新型流场结构及提高进气温度、速度可以提高气体的均匀性；采用自增湿方式可以简化电堆结构等解决方法，以期对燃料电池车的进一步发展起到引导作用。     

肉桂特色资源加工利用产业发展现状

肉桂是我国特色经济林树种，我国肉桂种植面积和年产量均居世界首位。我国肉桂主要分布在两广地区，其中广西为14.9万hm²，广东为8.9万hm²，两地面积占全国肉桂分布总面积的95%以上。肉桂既是著名的香料又是传统的名贵中药，具有极高的经济价值，发展肉桂产业对于促进农民增收、维护健康中国有着重要的意义。本研究综述了肉桂资源量、分布情况及主要利用部位，介绍肉桂主要产品（如桂皮，桂枝，肉桂粉及肉桂油）及加工技术现状、产品质量控制及其分析检测方法，分析了产业未来的发展趋势，并提出了产业发展的对策和措施：加强肉桂标准化示范基地建设，提高优质资源供给能力；提高肉桂加工利用技术水平，延长产业链；培育肉桂龙头企业，提高产品市场竞争力。为我国肉桂特色资源加工利用产业的可持续发展提供一定的思路。     

GIS气体高压开关在阳煤五矿变电站的应用

针对阳煤五矿广场变电站的高压开关老化问题,为了保证安全性,采用了GIS气体的高压绝缘开关进行了改造。在改造后,变电站的安全性得到了显著提高,设备运行可以节省成本200多万元。     

BIM技术在地下工程中的应用分析及展望

BIM技术以三维设计为基础,以数字信息为载体,将建筑信息贯穿于建筑的全生命周期中。然而由于地下工程的内部结构较为复杂,受地质条件影响较大,BIM技术在地下工程中的应用并不多见。叙述了BIM技术在隧道、地铁和矿井建设几种地下工程中应用的现状,并对几个典型案例进行分析,指出了BIM技术在地上工程和地下工程中应用的异同。最后,提出了目前BIM技术在地下工程中应用的问题以及对未来发展的建议。为推动BIM在我国地下工程中更广泛深入的应用提供重要参考价值。