水电站大型竖井施工安全风险控制措施研究

竖井是大型水电工程中广泛采用的重要建筑物,但竖井的传统施工方法存在施工程序复杂、人工劳动强度大、施工效率不高等特点,同时还存在较大的安全风险。通过对杨房沟水电站大型竖井施工过程的研究,总结出精细化控制爆破、小溜渣井施工方式,同时也设计了一套用于运输的综合提升系统。采用上述创新方法不仅减少了繁琐的施工程序,降低了安全施工风险,而且大量采用机械化手段进一步提高了施工效率,确保了该工程竖井施工的安全风险可控。相关措施可为类似工程的竖井施工提供较好的借鉴作用。     

来流马赫数影响高负荷扇形扩压叶栅气动性能的研究

为研究亚音速高负荷扇形扩压叶栅NACA0065-K48的变工况性能,采用数值方法研究了来流马赫数对叶栅气动性能和流场结构的影响,来流马赫数的取值范围为0.3～0.8。计算结果表明:随着来流马赫数的增大,叶栅静压比不断提高,但总压损失先减后增,马赫数在0.5～0.7范围内叶栅具有较好的综合气动性能。扇形叶栅下角区分离程度大于上角区的不平衡流动现象会随着马赫数的增大而加剧,通道涡则是这一发展趋势的主导,且马赫数达到0.7之后,下角区通道涡与集中脱落涡趋于融合。此外,下端壁分离螺旋点的形成与发展是控制下角区分离程度和损失大小的关键。     

Nanoconfined (Bio)Catalysts as Efficient Glucose‐Responsive Nanoreactors

Herein, the design, synthesis, and characterization of bifunctional hybrid nanoreactors used for concurrent one‐pot chemoenzymatic reactions are shown. In the design, the enzyme, glucose oxidase, is wrapped with a peroxidase‐mimetic catalytic polymer. Hemin, the organic catalyst, is linked to the flexible polymeric scaffold through coordination to the imidazole groups that hang out the network. This spatial arrangement, which works as a metabolic channel, is optimized for cooperative chemoenzymatic reactions in which the enzyme catalyzes first. A deep characterization of the integrated nanoreactors demonstrates that the confinement of two distinct catalytic sites in the nanospace is very effective in one‐pot reactions. Moreover, besides its role as scaffold material, the polymeric mantel protects both the biocatalyst and the chemical catalyst from degradation and inactivation in the presence of organic solvents. Furthermore, the polymeric environment of the nanoreactors can be tailored in order to trigger the assembly of those into highly active heterogeneous hybrid catalysts. Finally, the new nanoreactors are applied to the efficient degradation of organic aromatic compounds using glucose as the only fuel.     

金沙江上游水电站应对白格堰塞湖灾害的措施及经验

2018年10月、11月,西藏自治区昌都市江达县白格村两次发生山体滑坡造成金沙江断流并形成白格堰塞湖,给金沙江上游沿岸人民生产生活设施造成巨大安全威胁和超过百亿元的经济损失。华电金沙江上游水电开发有限公司组织所属企业及参建单位快速应对,采取撤离避让、工程防护、人工干预、生产恢复,推动后续处置、风险评估等措施,最大限度减轻了对金沙江上游叶巴滩、拉哇、巴塘、苏洼龙等在建水电站的灾害损失和后续影响,为类似灾害的处置提供借鉴经验。     

The impact of hydrogen refueling station subsidy strategy on China's hydrogen fuel cell vehicle market diffusion

Lack of hydrogen refueling stations (HRSs) has hindered the diffusion of hydrogen fuel cell vehicles (HFCVs) in the Chinese transport market. By combining the agent-based model (ABM) and the experience weighted attraction (EWA) learning algorithm, this paper explores the impact of government subsidy strategy for HRSs on the market diffusion of HFCVs. The actions of the parties (government, HRS planning department and consumers) and their interactions are taken into account. The new model suggests dynamic subsidy mode based on EWA algorithm yields better results than static subsidy mode: HFCV purchases, HRS construction effort, total number of HRSs and expected HRS planning department profits all outperform static data by around 27%. In addition, choosing an appropriate initial subsidy strategy can increase the sales of HFCVs by nearly 40%. Early investment from government to establish initial HRSs can also increase market diffusion efficiency by more than 76.7%.     

袁河新泉乡段梯级溢流堰水动力模拟及侵蚀分析

为了分析梯级溢流堰对袁河新泉乡段河道行洪及河床抗冲的影响,优化河道治理工程中溢流堰布置,建立了将拦河溢流堰作为闭边界条件的二维水动力数值模型,采用非结构化网格的有限体积法,对比分析了十年一遇洪水情况下梯级溢流堰建设前后河道水动力、河道水位、流场沿程变化特征,讨论了溢流堰布置对河道防洪及冲刷的影响。结果表明,在十年一遇洪水情况下溢流堰会抬升河道水位,平均增加0.49 m,满足河道行洪要求;梯级溢流堰使河道整体形成人工“阶梯深潭”体系,河道流速在空间上发生明显的异质性,堰上流速下降幅度较堰下流速大;水流发生急流与缓流之间交替,水流紊动强烈,加剧了水流能量损失,有效降低流速,减轻了河道冲刷,有利于稳定河岸结构。     

西藏水电开发是应对治理揠塞湖的重要举措

西藏区域地质构造发育,又属于高震区,在局部强降雨强降雪等恶劣小气候条件下,自然灾害频发,在高山深谷的江河上尤其容易发生堰塞湖。2018年10月17日凌晨5:00左右,西藏林芝加拉村下游约6km处(大峡谷核心区、无人区)雅鲁藏布江(以下简称“雅江”)左岸发生大规模泥石流,造成干流断流,形成影响很大的雅江加拉村堰塞湖。堰塞湖的治理一直是个世界难题,本文从2018年10月17日治理分析加拉堰塞湖的实践,阐述从水电开发角度,在灾害区上游建设高坝大库拦水调蓄,水库下游再采取截弯取直方式引走来水,作为防治雅江大峡谷河段今后可能出现大型堰塞湖重要治理手段,防止大型堰塞湖造成水淹城乡和溃堰水淹下游灾难的发生,从而达到既推进雅江水电开发,又较好治理了大峡谷河段自然灾害,实现把水电开发建成“功在当代,利在千秋”的减灾防灾工程。     

引水式水电站变顶高尾水洞水力特性和体型优化

考虑引水式水电站常用的有压尾水洞和变顶高尾水洞两类布置型式,采用基于特征线法的有压管道瞬变流分析模型和适用于明满流过渡过程分析的改进狭缝法模型,分别分析系统的过渡过程特性和尾水洞体型参数的敏感性,研究不同的尾水洞型式下尾水系统的水力特性,进一步揭示了变顶高尾水洞的底宽、洞高和顶坡对尾水管进口最小内水压力的影响规律。结果表明,与增大面积的有压尾水洞比较,变顶高尾水洞是一种可行的布置型式,可有效提高尾水管进口的最小内水压力且水锤过程衰减较快;合理增大变顶高尾水洞底宽、洞高或顶坡均可不同程度地改善尾水管进口最小内水压力,其中顶坡的影响相对明显,为体型优化设计提供了参考依据。     

A Topical Formulation of Melatoninergic Compounds Exerts Strong Hypotensive and Neuroprotective Effects in a Rat Model of Hypertensive Glaucoma

Melatonin is of great importance for regulating several eye processes, including pressure homeostasis. Melatonin in combination with agomelatine has been recently reported to reduce intraocular pressure (IOP) with higher efficacy than each compound alone. Here, we used the methylcellulose (MCE) rat model of hypertensive glaucoma, an optic neuropathy characterized by the apoptotic death of retinal ganglion cells (RGCs), to evaluate the hypotensive and neuroprotective efficacy of an eye drop nanomicellar formulation containing melatonin/agomelatine. Eye tissue distribution of melatonin/agomelatine in healthy rats was evaluated by HPLC/MS/MS. In the MCE model, we assessed by tonometry the hypotensive efficacy of melatonin/agomelatine. Neuroprotection was revealed by electroretinography; by levels of inflammatory and apoptotic markers; and by RGC density. The effects of melatonin/agomelatine were compared with those of timolol (a beta blocker with prevalent hypotensive activity) or brimonidine (an alpha 2 adrenergic agonist with potential neuroprotective efficacy), two drugs commonly used to treat glaucoma. Both melatonin and agomelatine penetrate the posterior segment of the eye. In the MCE model, IOP elevation was drastically reduced by melatonin/agomelatine with higher efficacy than that of timolol or brimonidine. Concomitantly, gliosis-related inflammation and the Bax-associated apoptosis were partially prevented, thus leading to RGC survival and recovered retinal dysfunction. We suggest that topical melatoninergic compounds might be beneficial for ocular health.     

基于复合相变材料的梯级组合蓄热特性研究

针对潜热蓄热装置内部相变材料（PCM）导热系数偏小，蓄热速率过低的问题，对基于复合相变材料的两级串联式梯级蓄热装置的相变过程进行了数值研究。通过对不同热物性PCM工况的对比与分析，得到了装置在不同工况下的蓄热特性。结果表明，存在最佳的热扩散系数，使固定熔点的PCM实现“均匀等速相变”。同时，增大PCM的热扩散系数可以有效降低加热面温度，但随着热扩散系数的增大，加热面温度降低幅度减小。通过分析Stefan数，得到了装置最佳的参数，使工况蓄热效果最佳。最后，通过Stefan数为2.88时的实验工况验证了相关规律的正确性。