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1.
Towards a Better Prediction of Cell Settling on Nanostructure Arrays—Simple Means to Complicated Ends 下载免费PDF全文
Nina Buch‐Månson Sara Bonde Jessica Bolinsson Trine Berthing Jesper Nygård Karen L. Martinez 《Advanced functional materials》2015,25(21):3246-3255
Vertical arrays of nanostructures (NSs) are emerging as promising platforms for probing and manipulating live mammalian cells. The broad range of applications requires different types of interfaces, but cell settling on NS arrays is not yet fully controlled and understood. Cells are both seen to deform completely into NS arrays and to stay suspended like tiny fakirs, which have hitherto been explained with differences in NS spacing or density. Here, a better understanding of this phenomenon is provided by using a model that takes into account the extreme membrane deformation needed for a cell to settle into a NS array. It is shown that, in addition to the NS density, cell settling depends strongly on the dimensions of the single NS, and that the settling can be predicted for a given NS array geometry. The predictive power of the model is confirmed by experiments and good agreement with cases from the literature. Furthermore, the influence of cell‐related parameters is evaluated theoretically and a generic method of tuning cell settling through surface coating is demonstrated experimentally. These findings allow a more rational design of NS arrays for the numerous exciting biological applications where the mode of cell settling is crucial. 相似文献
2.
This paper addresses the nonlinear stress-strain response in glass fibre non-crimp fabric reinforced vinylester composite laminates subjected to in-plane tensile loading. The nonlinearity is shown to be a combination of brittle and plastic failure. It is argued that the shift from plastic to brittle behaviour in the vinylester is caused by the state of stress triaxiality caused by the interaction between fibre and vinylester. A model combining damage and plasticity is calibrated and evaluated using data from extensive experimental testing. The onset of damage is predicted using the Puck failure criterion, and the evolution of damage is calibrated from the observed softening in plies loaded in transverse tension. Shear loading beyond linear elastic response is observed to result in irreversible strains. A yield criterion is implemented for shear deformation. A strain hardening law is fitted to the stress-strain response observed in shear loaded plies. Experimental results from a selection of laminates with different layups are used to verify the numerical models. A complete set of model parameters for predicting elastic behaviour, strength and post failure softening is presented for glass fibre non-crimped fabric reinforced vinylester. The predicted behaviour from using these model parameters are shown to be in good agreement with experimental results. 相似文献
3.
This paper discusses the effects of the grinding-induced cyclic heating on the properties of the hardened layer in a plunge cylindrical grinding process on the high strength steel EN26. It was found that a multi-pass grinding brings about a uniform and continuous hardened layer along the circumference of the cylindrical workpiece. An increase of the number of grinding passes, leads to a thicker layer of hardening, a larger compressive residual stress and a deeper plastic deformation zone. Within the plastic deformation zone, the martensitic grains are refined by the thermo-mechanical loading, giving rise to a hardness of 12.5% higher than that from a conventional martensitic transformation. The coupled effects of heat accumulation and wheel wear in the multi-pass grinding are the main causes for the thickening of the hardened layer. A too small infeed per workpiece revolution would result in insufficient grinding heat, and in turn, bring about an undesirable tempered hardened layer and a reduction of its hardness. 相似文献
4.
Deformation behavior of stoichiometric blends made from poly(styrene-co-styrenesulfonic acid) (SPS) and poly(styrene-co-4-vinylpyridine) (SVP) was investigated by TEM observation of strained thin films. An FTIR investigation revealed that ionic cross-links were formed between the component polymers upon blending due to intermolecular ion-ion interactions, which arose from proton transfer from sulfonic acid groups to pyridine groups. TEM observations indicate that the deformation mode of the blends changed from crazing only to crazing plus shear deformation, with the shear contribution becoming larger, as the ion content in the blends increased. Such changes in deformation mode can be understood as arising from an increase in the ‘effective’ strand density due to the formation of ionic cross-links upon blending. It was also found that the ionic cross-links via pyridinium cation/sulfonate anion ion pairs were more effective in inducing the transition of deformation mode than ionic cross-links via -SO3−/Na+ or -SO3−/Ca2+ ion pairs. 相似文献
5.
WC/Cu复合材料制备及其高温性能 总被引:11,自引:0,他引:11
用机械合金化法结合冷变形,制备了WC/Cu复合材料,研究了冷变形后复合材料的组织特征和高温退火时韵性能变化。结果表明:烧结后的材料经冷变形,组织呈显著纤维状,WC颗粒弥散分布,密度明显提高,达到理论密度的99.2%;复合材料经600~900℃高温退火,强度和硬度略有下降,塑性则有大幅提高;900℃退火时未发生明显的再结晶,界面结合良好;所制备的WC/Cu复合材料有优良的综合性能。 相似文献
6.
7.
加快塑料技术中心建设提高新产品开发水平 总被引:2,自引:2,他引:0
对中国石油化工集团公司(简称中国石化)合成树脂生产及加工应用技术的现状进行了分析,指出中国石化应加快建设塑料加工应用技术中心,为塑料产品的加工用户提供高技术水平和快捷周到的技术服务,在合成树脂新产品开发和产品结构调整中发挥积极作用,以提高合成树脂产品的市场竞争力。 相似文献
8.
本文就利用诸如蛋白石这样的疏松多孔矿料同灰土构成的混合料,在路面结构中表现出的独特有效的抗冻作用机理作了深入分析,并结合足尺试验数据加以验证。阐述了所谓多孔板体结构的概念、机制和材料组成要求。 相似文献
9.
介绍了日本川崎制铁公司技术研究所开发出的电焊钢管采用热张力减径工艺的特性 ,及这种钢管的高强度、高延性等基本特性。用这种钢管制造的汽车零部件 ,经弯曲、冲击和疲劳特性等实验 ,证明具有良好的机械加工性能 ,是制造汽车用零部件的优良材料。 相似文献
10.
广州地铁一号线隧道结构变形监测及成果分析 总被引:5,自引:0,他引:5
介绍了广州地铁一号线运营以来的全线隧道结构变形监测 ,分析了隧道结构的安全状况和各种变化规律 ,并对其变形原因进行有益的探讨 相似文献