真空制盐蒸发结晶器的设计与实践

真空蒸发制盐外热式强制逆循环轴向出料蒸发结晶器，经多个厂家生产应用实践证明是成功的，具有生命力的。这种新型结构，作为一项新技术新设备应加强研究，总结提高，推广应用。不断完善。文章从流体力学、结晶机理角度要求，到具体工程设计参数和材质选用。论述了该罐的特点。     

室温固化型不粘涂料的研究

研究了双组分室温固化型低表面能氟涂层的配合技术,所用材料的物化特性;讨论了基料、填料、助剂等对氟涂料的影响机理。实验结果表明:氟涂层的表面能为10.6 mJ/m2,疏水角可达到122°,附着力为1级、硬度为4H,同时涂层具有耐腐蚀和耐化学性等性质。     

On the importance of some surface and interface characteristics in the formation of the properties of adhesive joints

The importance of some relative surface characteristics which determines the strength of adhesive joints: specific surface of substrate , relative contact area β and specific contact area β in the adhesion interaction process were emphasised. Existing and potential methods of experimental evaluation of these characteristics were shortly analysed. The durability of the adhesive joints in water media significantly increases with growth of specific surface ^* of chemically treated substrate evaluated from the SEM micrographs. Specific surface calculated from the experimental data of hexane adsorption measurements for iron particles (particulate model of steel substrate) is more then ten times greater than respective ^* values. The relative contact area β of the Al₂O₃ particles (in wide range of ) with PE melt was in a roundabout way evaluated by experimental determination of the affect of on kinetic of peel strength formation of adhesive joints: Al₂O₃ filled PE-steel. The speculation was based on the ability of Al₂O₃ to adsorb low-molecular products of contact oxidation of PE which takes place in the process of formation of adhesive joints and determines their strength. The ability of sorption in its turn is proportional to efficient value of β. The availability of the Al₂O₃ surface was evaluated.     

多降液管结晶罐的循环比的确定

结晶罐的循环比是否合理,反映了结晶罐结构性能的优劣。本文通过对糖膏在结晶罐中流动的压力降的分析,讨论了多降液管结晶罐的循环比的理论计算,并提出了等比例的校正方法,使整个计算过程变得非常简单。     

薄煤层大功率刮板输送机的研制

介绍了薄煤层大功率刮板输送机ＳＧＢ６３０／２×７５Ｈ型输送机的设计及结构特点。     

Nanosponge-based pediatric-controlled release dry suspension of Gabapentin for reconstitution

Abstract

Context: Gabapentin was selected to formulate oral controlled release dry suspension because of short biological half life of 5–7?h and low bioavailability (60%). Gabapentin is a bitter drug so an attempt was made to mask its taste.

Objective: To formulate and evaluate controlled release dry suspension for reconstitution to increase the bioavailability and to control bitter taste of drug.

Materials and methods: Cyclodextrin based nanosponges were synthesized by previously reported melt method. The nanosponge–drug complexes were characterized by FTIR, DSC and PXRD as well as evaluated for taste and saturation solubility. The complexes were coated on Espheres by a suspension layering technique followed by coating with ethyl cellulose and Eudragit RS-100. A dry powder suspension for reconstitution of the microspheres was formulated and evaluated for taste, redispersibility, in vitro dissolution, sedimentation volume, leaching and pharmacokinetics.

Results and discussion: The complexes showed partial entrapment of drug nanocavities. Significant decrease in solubility (25%) was observed in the complexes than pure drug in different media. The microspheres of nanosponge complexes showed desired controlled release profile for 12?h. Insignificant drug leaching was observed in reconstituted suspension during storage for 7 days at 45?°C/75% RH. Nanosponges effectively masked the taste of Gabapentin and the coating polymers provided controlled release of the drug and enhanced taste masking. The results of in vivo studies showed increase in bioavailability of controlled release suspension by 24.09% as compared to pure drug.

Conclusion: The dry powder suspension loaded with microspheres of nanosponges complexes can be proposed as a suitable controlled release drug delivery for Gabapentin.     

黄河流域：商丘城市空间营造

该文是个案研究系列之泛黄河流域商丘城市空间营造研究,对商丘城市族群的更替叠累及城市空间营造进行了分析研究.     

谈工程量清单计价下的合同管理与结算的关系

对清单计价规范实施后,工程量计价模式下的工程合同管理与结算的关系进行了探讨,总结了加强工程量清单结算管理的措施和工程价款结算争议处理方法,最后指出加强施工合同的管理,对提高工程结算的效率和质量具有重要作用。     

基于混合FE-SEA法的镁质油底壳隔声数值优化

用混合FE-SEA法分析相同厚度的钢、铝合金和镁合金三种材质油底壳的隔声量,综合考虑轻量化和降噪的要求,提出降噪效率的概念,将其作为评价指标,结果显示镁质油底壳的综合性能最为优越。为了更进一步改善镁质油底壳的隔声效果,对隔声低谷处的模态贡献量进行分析,找出隔声低谷的关键参与模态。通过调取该频率处的速度振型,识别出油底壳上严重振动区域,在此区域内表面添加加强筋,有效地抑制了振动,同时低谷处的隔声也得到明显的改善。     

某柴油机油底壳仿真计算分析

本文利用ABAQUS结构仿真软件对某发电用柴油机油底壳进行模态、强度计算。在发动机实际运行工况下,油底壳底部为悬空状态,模态计算结果显示油底壳一阶模态距发动机点火激励频率点较近,低于激励频率的1.2倍,模态不满足设计要求;在发动机装配过程中,油底壳底部压在装配台上,发动机在上下方向三倍的重力加速度冲击载荷工况下,油底壳产生的应力最大值低于对应材料的屈服强度极限,强度满足设计要求。通过对油底壳两种状态下的仿真分析,验证和确保了油底壳结构设计的可行性,有效避免了发动机装配和实际运行过程中故障的发生。