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1.
External apical root resorption (EARR) is one of the most serious complications associated with orthodontic treatment. The aim of the study was to analyze the relationships between selected single nucleotide polymorphisms (SNPs) in Interleukin 1 receptor antagonist (IL1RN), purinoreceptor P2X7 (P2RX7) and EARR in patients after orthodontic treatment. The study comprised 101 patients who underwent a complex orthodontic treatment with a combination of fixed appliances. Roots were measured based on orthopantomograms and lateral cephalometric radiographs taken before and at the end of the treatment using diagnostic software. Proportional measurements of selected teeth were made using the modified Linge and Linge methods. Based on the presence or absence of EARR, patients were divided into two groups: control group, 61 patients without EARR (with 0.90 ≤ rRCR ≤ 1.00), and EARR group, 40 patients with EARR (rRCR < 0.90). Root resorption in selected groups was also evaluated with the scores of Malmgren and Levander. SNP analysis was performed using the real-time polymerase chain reaction (PCR) method. The analysis indicated that a specific haplotype of P2RX7 (rs208294) and IL1RN (rs419598) modified the risk of EARR development (p < 0.05), with a Bonferroni correction. The analysis of the P2RX7 and IL1RN gene polymorphisms showed that the presence of SNPs of these genes may predispose individuals to EARR. These findings indicate that EARR is a complex condition influenced not only by environmental factors and needs further study on the genetic risk factors.  相似文献   
2.
The goal of this study was to determine corrosion behavior of three orthodontic wires based on nickel‐titanium alloy (NiTi) in artificial saliva at temperature of 37 °C as function of immersion time. Following orthodontic wires were used: uncoated (NiTi), rhodium coated (Rh NiTi) and nitrified (N NiTi) orthodontic wires. Corrosion of investigated orthodontic wires were monitored by measuring of Ni2+ and Ti4+ ions released in artificial saliva by inductively coupled plasma‐optical emission spectroscopy (ICP‐OES) after 3, 7, 14, 21 and 28 days of immersion. Obtained results indicate that corrosion reaction of the NiTi wires in artificial saliva follows the parabolic rate law. According to the obtained values of parabolic corrosion rate constants, corrosion susceptibility of orthodontic wires decreases in the following order: Rh NiTi wire (Kp = 2.48 μg2/cm4 h) > NiTi wire (Kp = 1.6 × 10–3 μg2/cm4 h) > N NiTi wire (Kp = 6.0 × 10–4 μg2/cm4 h). These results indicate that in comparison with uncoated NiTi wire, rhodium coating significantly increases corrosion susceptibility, while nitrification effectively suppresses the release of Ni2+ and Ti4+ ions.  相似文献   
3.
利用射频磁控溅射制备了氮掺杂TiO2-xNx薄膜托槽,通过X射线衍射(XRD)、扫描电镜(SEM)等测试手段表征了托槽表面薄膜的结构、形貌,并通过原子力显微镜(AFM)、多功能材料表面试验仪等研究了TiO2-xNx薄膜与基底托槽的附着力、TiO2-xNx薄膜托槽的表面粗糙度以及表面摩擦系数。结果表明制备的托槽表面为均一的锐钛矿相结构TiO2-xNx薄膜,晶粒粒径为30nm,纳米TiO2-xNx薄膜托槽表面致密、平整,薄膜与托槽衬底结合紧密、附着性好,托槽表面粗糙度降低,摩擦系数变小,改善了托槽表面性能,为抗菌性研究奠定了基础。  相似文献   
4.
对镍钛合金弓丝、β-钛合金弓丝、澳丝和国产不锈钢弓丝这4种正畸弓丝的弯制特性进行了分析。采用MSC.Marc有限元分析软件根据实际弯制方法建立弓丝弯制有限元模型并进行仿真分析,结合弯制实验得到4种正畸弓丝的回弹特性曲线,并对实验结果进行了对比。结果表明,镍钛合金弓丝、β-钛合金弓丝、澳丝和国产不锈钢弓丝这4种正畸弓丝的回弹性依次减小,回弹角随着弯制角度的增加而增大;有限元仿真结果和实验结果基本一致。采用弓丝弯制机器人在弓丝回弹特性的基础上进行弓丝弯制,固定夹具和移动夹具的距离t=2mm时的拟合曲线要优于t=10mm时的拟合曲线;因此在使用弓丝弯制机器人弯丝时要尽量减小固定夹具和移动夹具之间的距离。  相似文献   
5.
Aim: The aim of this study was to evaluate the antibacterial effects of five orthodontic bonding materials commonly used in orthodontics. Materials and Methods: The antibacterial effects of five orthodontic bonding materials were evaluated against Streptococcus mutans and Streptococcus salivarius by direct contact test (DCT). Using the DCT technique, quintet specimens of Transbond XT, Blugloo, Grengloo, Light Bond, and Opal Bond were applied to the bottom and the walls of the five wells of a 96-microtiter plate with a height of 2 mm. Samples were prepared in two sets: 1-day samples and 7-day samples. Ten microliters of bacterial suspension were added to each well for direct contact with each material for 1h at 37 °C. Bacterial growth was then measured in a microplate spectrophotometer hourly at 600 nm for 24 h. Five uncoated wells with identical inoculum sizes served as positive controls. The data obtained at the end of 24 h was statistically analyzed with one-way ANOVA, and post hoc comparisons were done using Tamhane’s T2 test. Results: Blugloo generally showed better antibacterial activity than the other materials. Transbond XT did not show any antibacterial activity. There was a statistically significant difference between Transbond XT and Light Bond in the 1-day sample against S. mutans (p < 0.05). No statistically significant differences were found among the other groups (p > 0.05). Conclusion: Blugloo had the most potent antibacterial activity against S. salivarious.  相似文献   
6.
介绍了一种在三维三角网格牙颌模型上半自动探测牙弓线的方法。首先使用三维激光测量系统对牙颌石膏模型进行测量获得数字模型;其次在网格模型上交互拾取4个参照点以确定咬合平面;接着使用顶点法矢和咬合平面作为参考,筛选出初始特征点并拟合出初始牙弓线;以初始牙弓线作为新的参考依据筛选出最终特征点,拟合最终参照点得到最终牙弓线。使用多副牙颌模型对该方法进行了测试,验证了该方法稳定、有效。  相似文献   
7.
A. Berradja  F. Bratu  L. Benea  J.-P. Celis 《Wear》2006,261(9):987-993
The dependence of the tribocorrosion of stainless steels AISI 304L and SS 3M® orthodontic archwires sliding against corundum in a Ringer's solution on applied normal force, and sliding velocity, has been investigated using in situ electrochemical noise measurements. Applied normal force and sliding velocity were found to greatly affect current and potential during fretting-corrosion. An increase in normal force and sliding velocity induce an increase in current and a decrease in potential accelerating the depassivation rate of the tested stainless steels. The fluctuations in potential and current during fretting-corrosion are more pronounced at increasing sliding frequency than at increasing applied normal force. Sliding wear affects the repassivation behaviour of the tested materials by increasing the anodic current in the wear track area.  相似文献   
8.
介绍了一种新型可见光固化正畸粘合剂的组成、性能及正畸粘接的工艺。此粘合剂由一种单组分液体底胶和单组分糊剂组成。与化学固化粘合剂相比,其操作使用方便,固化时间短。这种新型粘合剂的粘接强度完全满足了正畸粘合剂的要求。  相似文献   
9.
程杭  张凌浩 《包装工程》2017,38(24):43-47
目的对儿童正畸服务中的深度体验设计与方法策略进行研究。方法通过深度体验设计方法将儿童牙科正畸服务的体验周期进行划分,并对其现状和案例进行分析和梳理,将各体验周期特点进行总结归纳。结论分析归纳出儿童牙科正畸服务深度体验周期中信息平台可视化认知阶段、情绪管理与情感感知连续性诊疗阶段、个人行为与健康生活关联性认同阶段、社区延续服务体验拓展阶段4个深度体验特征,并根据特征的内涵提炼出在深度体验设计指导下对于信息知识认知、正向体验、生活方式及价值获取几个方面服务体验设计策略,为今后的研究提供理论指导。  相似文献   
10.
Autophagy (cellular self-consumption) is a crucial adaptation mechanism during cellular stress conditions. This study aimed to examine how this important process is regulated in human periodontal ligament (PDL) fibroblasts by mechanical and inflammatory stress conditions and whether the mammalian target of rapamycin (mTOR) signaling pathway is involved. Autophagy was quantified by flow cytometry. Qualitative protein phosphorylation profiling of the mTOR pathway was carried out. Effects of mTOR regulation were assessed by quantification of important synthesis product collagen 1, cell proliferation and cell death with real-time PCR and flow cytometry. Autophagy as a response to mechanical or inflammatory treatment in PDL fibroblasts was dose and time dependent. In general, autophagy was induced by stress stimulation. Phosphorylation analysis of mTOR showed regulatory influences of mechanical and inflammatory stimulation on crucial target proteins. Regulation of mTOR was also detectable via changes in protein synthesis and cell proliferation. Physiological pressure had cell-protective effects (p = 0.025), whereas overload increased cell death (p = 0.003), which was also promoted in long-term inflammatory treatment (p < 0.001). Our data provide novel insights about autophagy regulation by mechanical and inflammatory stress conditions in human PDL fibroblasts. Our results suggest some involvement of the mTOR pathway in autophagy and cell fate regulation under the named conditions.  相似文献   
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