基于卓越工程师教育的频率特性分析课堂教学研究

频率特性分析在工程应用中具有重要的作用,在电路分析、模拟电子技术、信号与系统、自动控制理论等相关课程中都涉及到相关章节内容,在不同课程中如何根据工程应用和学生学习阶段把握具体的讲解内容和讲解方式非常重要。本文从频率特性的求解方法和具体物理意义角度开展在不同课程中讲解的方法,从时域和频域角度分别讨论其物理意义和具体的分析方法。通过渐进深化的教学过程和教学方法不断提高学生的知识掌握和应用技能,提高学生的工程意识、工程素质和工程创新能力,强化学生对于频率特性课程知识的综合应用能力。     

PID Control of Planar Nonlinear Uncertain Systems in the Presence of Actuator Saturation

This paper investigates PID control design for a class of planar nonlinear uncertain systems in the presence of actuator saturation. Based on the bounds on the growth rates of the nonlinear uncertain function in the system model, the system is placed in a linear differential inclusion. Each vertex system of the linear differential inclusion is a linear system subject to actuator saturation. By placing the saturated PID control into a convex hull formed by the PID controller and an auxiliary linear feedback law, we establish conditions under which an ellipsoid is contractively invariant and hence is an estimate of the domain of attraction of the equilibrium point of the closed-loop system. The equilibrium point corresponds to the desired set point for the system output. Thus, the location of the equilibrium point and the size of the domain of attraction determine, respectively, the set point that the output can achieve and the range of initial conditions from which this set point can be reached. Based on these conditions, the feasible set points can be determined and the design of the PID control law that stabilizes the nonlinear uncertain system at a feasible set point with a large domain of attraction can then be formulated and solved as a constrained optimization problem with constraints in the form of linear matrix inequalities (LMIs). Application of the proposed design to a magnetic suspension system illustrates the design process and the performance of the resulting PID control law.      

Domain reversal and current transport property in BiFeO3 films

The electrical properties and domain reversal in BiFeO₃ ferroelectric films were studied using sandwiched heterostructures and piezoresponse force microscopy. A robust polarization state was observed, combined with a switchable domain pattern and a remanent polarization of approximately 100 μC cm^?2. In addition, domain reversal was explored using scanning probe microscopy. The results show that dipoles could be reversed along the direction of the electric field under a negative tip bias, leading to carrier gathering near the domain walls. The enhanced conductivity near the domain walls was owing to the discontinuous polarization boundary conditions. In addition, typical diode-like current transport properties are sensitive to various temperature conditions, which is attributed to the Schottky barriers at the contact interface. These findings extend the current understanding of domain texture reversal in ferroelectric films and shed light on their potential applications for future ferroelectric random-access memory operations over a wide temperature range.     

The effects of washing a collagen sample prior to TEM examination

Transmission electron microscopy (TEM) is an important analysis technique to visualize (bio)macromolecules and their assemblies, including collagen fibers. Many protocols for TEM sample preparation of collagen involve one or more washing steps to remove excess salts from the dispersion that could hamper analysis when dried on a TEM grid. Such protocols are not standardized and washing times as well as washing solvents vary from procedure to procedure, with each research group typically having their own protocol. Here, we investigate the influence of washing with water, ethanol, but also methanol and 2-propanol, for both mineralized and unmineralized collagen samples via a protocol based on centrifugation. Washing with water maintains the hydrated collagen structure and the characteristic banding pattern can be clearly observed. Conversely, washing with ethanol results in dehydration of the fibrils, often leading to aggregation of the fibers and a less obvious banding pattern, already within 1 min of ethanol exposure. As we show, this process is fully reversible. Similar observations were made for methanol and propanol. Based on these results, a standardized washing protocol for collagenous samples is proposed.     

Transparent tetragonal-cubic zirconia composite ceramics densified by spark plasma sintering and hot isostatic pressing

Targeting higher toughness transparent ceramics, tetragonal (3 mol % yttria) and cubic (8 mol % yttria) ZrO₂ starting powder mixtures were densified by spark plasma sintering (SPS) in vacuum at 1100 °C and post hot isostatic pressing (HIP) in argon at 1100 °C. The influence of the ultra-fine microstructure and phase composition on the fracture resistance and light transmission in the visible and infra-red range was assessed. Of special interest was the influence of a thermal annealing step in air on the transparency of the SPS and SPS-HIP ceramics.     

Exploring Molecular Contacts of MUC1 at CIN85 Binding Interface to Address Future Drug Design Efforts

The modulation of protein-protein interactions (PPIs) by small molecules represents a valuable strategy for pharmacological intervention in several human diseases. In this context, computer-aided drug discovery techniques offer useful resources to predict the network of interactions governing the recognition process between protein partners, thus furnishing relevant information for the design of novel PPI modulators. In this work, we focused our attention on the MUC1-CIN85 complex as a crucial PPI controlling cancer progression and metastasis. MUC1 is a transmembrane glycoprotein whose extracellular domain contains a variable number of tandem repeats (VNTRs) regions that are highly glycosylated in normal cells and under-glycosylated in cancer. The hypo-glycosylation fosters the exposure of the backbone to new interactions with other proteins, such as CIN85, that alter the intracellular signalling in tumour cells. Herein, different computational approaches were combined to investigate the molecular recognition pattern of MUC1-CIN85 PPI thus unveiling new structural information useful for the design of MUC1-CIN85 PPI inhibitors as potential anti-metastatic agents.     

频率域八阶NAD有限差分模拟及全波形反演

全波形反演是一种利用波动方程与最优化算法定量获取地下介质物性参数的高分辨率成像方法。正演模拟是反演的基础，为进一步提高正演计算效率，提出用八阶频率域近似解析离散化（NAD）方法离散二维声波方程，详细推导了高阶NAD格式的构造过程，并采用一类不精确旋转分块三角预处理算子加速Krylov迭代方法求解离散后得到的大型稀疏线性代数方程组。波场模拟与数值频散分析结果体现了该方法在压制数值频散和提高计算效率方面的优势，即每个波长少于2个点即可准确恢复波场，突破了采样频率极限。运用所构造的正演算法进行反演，并对两种典型的分层介质模型和Marmousi模型进行频率域全波形反演，得到了高分辨率、高保真的计算结果，结合反演误差曲线验证了所提方法的有效性和适用性。     

基于时频域的卷积神经网络运动想象脑电信号识别方法

针对目前运动想象脑电（EEG）信号识别率较低的问题，考虑到脑电信号蕴含着丰富的时频信息，提出一种基于时频域的卷积神经网络（CNN）运动想象脑电信号识别方法。首先，利用短时傅里叶变换（STFT）对脑电信号的相关频带进行预处理，并将多个电极的时频图组合构造出一种二维时频图；然后，针对二维时频图的时频特性，通过一维卷积的方法设计了一种新颖的CNN结构；最后，通过支持向量机（SVM）对CNN提取的特征进行分类。基于BCI数据集的实验结果表明，所提方法的平均识别率为86.5%，优于其他传统运动想象脑电信号识别方法；同时将该方法应用在智能轮椅上，验证了其有效性。     

相似系数阈值滤波的数据驱动控制束偏移

高斯束偏移不仅具有接近波动方程偏移的精度，而且具有Kirchhoff偏移灵活、高效的特点。然而当实际地震采集数据中含有较强噪声时，易产生偏移假象而影响成像质量。为此，在传统高斯束偏移的基础上，根据有效信号和干扰信号在τ-p域中的相干性差异，发展了一种基于相似系数阈值滤波的数据驱动控制束偏移方法。采用数据驱动策略，在高斯束偏移成像过程中，先计算τ-p道集的相似系数，再通过设定相似系数阈值控制干扰信号，从而降低偏移剖面中的随机噪声；控制束偏移可以直接提取角度域共成像点道集，无需复杂的角度映射变换且具有更高信噪比。模型测试及实际资料处理结果表明：对于低信噪比数据，控制束偏移剖面的信噪比明显高于常规高斯束偏移，但会损失相对振幅的可靠性；尽管控制束偏移在τ-p道集的滤波过程增加了一定的计算量，但总体与常规高斯束偏移方法的计算效率相当；相似系数阈值参数选取十分关键，阈值较小时偏移噪声较强，但过大阈值也可能压制部分有效信息或产生偏移假象，选取合适的阈值参数才能得到较理想的偏移剖面。     

重庆下古生界页岩顺层滑脱变形域的形成及其地质意义

在野外露头和岩心观察基础上，通过力学分析，对重庆下古生界页岩中顺层滑脱变形域的类型、特征及其形成进行了研究，并结合页岩气勘探实践，对其地质意义进行了探讨。顺层滑脱变形域包括挤压型和重力型两类。挤压型顺层滑脱变形域形成时水平挤压构造应力占主导地位，岩层发生“逆断层”运动；重力型顺层滑脱变形域形成时上覆地层压力占主导地位，岩层发生"正断层"运动。挤压型顺层滑脱变形域地层变形相对较强，影响范围相对较大。埋藏深度和岩层倾角是控制同一地区同一页岩层中顺层滑脱变形域形成的关键地质要素。页岩埋深越大，形成挤压型顺层滑脱变形域时的临界岩层倾角越大，而形成重力型顺层滑脱变形域的临界岩层倾角则越小。重力型顺层滑脱变形域破坏页岩气保存条件。背斜构造部位挤压型顺层滑脱变形域所形成的顺层破碎带和网状裂缝系统是页岩气重要的运移通道和储集空间，向斜构造部位挤压型顺层滑脱变形域所形成的顺层破碎带和网状裂缝系统成为页岩气向临近背斜构造部位运移或向地表散失的重要通道。