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Production of ursolic acid, the anti-hepatitis effective composition from natural plant, Sambucus chinensis Lindl. was carried out and the scale-up preparation technology was studied. Extraction of the herb Sambucus chinensis Lindl. was extracted in reflux with 7 volume times of refluxing ethanol at 80℃ for 1 h for two times. The extract was purified with a seh-made specific impurity remover "YCXY-1" to yield ursolic acid of high purity. A new "Extraction/Gelation" technology for the production of ursolic acid was developed. The specific impurity remover "YCXY-1" showed high effectiveness in purification. The purity of the mass-produced ursolie acid was up to 99.8%. The chemical structure of the product was confirmed by the physicochemical constants and spectroscopic identification. The production of high-purity ursolic acid was optimized with natural plant as raw material and with only ethanol as extracting solvent. The difficulties such as isolation and impurity removal were addressed effectively. The novel technology is reasonable, convenient, practical, low-cost, high-yield, suitable for mass production. 相似文献
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薯蓣属植物的研究开发现状 总被引:3,自引:0,他引:3
阐述了薯蓣皂苷元的发现和利用,薯蓣植物的资源状况,薯蓣属植物的化学成分及薯蓣皂苷元的提取工艺,薯蓣皂苷的开发利用前景与经济价值。 相似文献
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