Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review

Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disorder, affecting around 25% of the population worldwide. It is a complex disease spectrum, closely linked with other conditions such as obesity, insulin resistance, type 2 diabetes mellitus, and metabolic syndrome, which may increase liver-related mortality. In light of this, numerous efforts have been carried out in recent years in order to clarify its pathogenesis and create new prevention strategies. Currently, the essential role of environmental pollutants in NAFLD development is recognized. Particularly, endocrine-disrupting chemicals (EDCs) have a notable influence. EDCs can be classified as natural (phytoestrogens, genistein, and coumestrol) or synthetic, and the latter ones can be further subdivided into industrial (dioxins, polychlorinated biphenyls, and alkylphenols), agricultural (pesticides, insecticides, herbicides, and fungicides), residential (phthalates, polybrominated biphenyls, and bisphenol A), and pharmaceutical (parabens). Several experimental models have proposed a mechanism involving this group of substances with the disruption of hepatic metabolism, which promotes NAFLD. These include an imbalance between lipid influx/efflux in the liver, mitochondrial dysfunction, liver inflammation, and epigenetic reprogramming. It can be concluded that exposure to EDCs might play a crucial role in NAFLD initiation and evolution. However, further investigations supporting these effects in humans are required.     

Reviews of clean coal conversion technology in China:Situations & challenges

It is important to develop the advanced coal to chemicals industry (ACCI) against a backdrop of coal-based energy structures,excessive imported oil and natural gas,and strict environmental con-straints in China.In this study,the technology and industry of China's ACCI are reviewed to explain the effect of using coal to replace oil and natural gas,and the corresponding resource and environmental burdens that this will create.Development trends in technology and industry are also proposed to explore future scenarios.The review shows that although excellent progress has been made on an indus-trial scale,demonstrative level,and in terms of technology and equipment,the lack of strategic under-standing,severe external constraints,partly underdeveloped technologies,and weak foundations must be immediately addressed.Therefore,it is necessary to clarify the importance that the ACCI has on the energy revolution and energy system.Based on technological innovation,a variety of external factors should be considered as a whole with emphasis on filling the knowledge gap of theoretical foundations and industry standards to support high-quality development for ACCI.     

废弃电子化学品处理处置标准现状及发展方向

重点介绍了废弃电子化学品定义、产生来源、处理处置现状、处理处置标准化现状及标准发展方向。从废弃电子化学品行业实际情况出发,具体分析了行业现状、处理处置水平及标准化工作的开展情况等。通过标准的制定实施,以及其创新驱动作用的发挥,规范了行业处理处置行为,推动行业科技进步,对全面提升废弃电子化学品处理处置技术水平,实现循环经济、绿色产业和资源化利用有着十分重要的作用。     

DCS在精细化工中的应用

对精细化工的特点进行了分析,介绍了DCS系统的配置、算法设计以及在安全控制方面的应用。     

浅探精细化学品化学课程教学改革

文章从精细化学品化学课程特点入手,结合学校周边精细化工产业的实际情况,对精细化学品化学课程教学改革进行探索和尝试。对教材和课程教学内容进行"精简化"和"多样化"相结合的改革,使其更好地与培养"应用型人才"的教学目的以及学生的学习期望相匹配。     

案例教学法在精细化学品化学教学中的应用研究

精细化学品化学是应用化学、化学工程与工艺专业的重要必修课程,此课程理论知识涵盖范围广,教师的授课任务重,学生的学习兴趣低。针对上述问题在教学中引入案例教学,不仅激发了学生的学习兴趣,而且培养了学生的创新精神和创新能力,提高了教学质量。     

中央空调低磷水处理剂的研究应用

随着近年来水处理药剂的发展和人们对环境要求的不断提高,无磷、低磷药剂的使用逐步受到大家的重视,天津某行政机关中央空调水处理系统原采用磷系药剂进行处理,针对其更换低磷药剂的问题,笔者研制低磷药剂复配配方,通过阻垢、缓蚀、动态实验反复印证配方的可行性,筛选出最佳药剂配方方案,并成功应用于现场,解决的该水处理系统的实际问题。     

危险化学品环境污染事故统计分析及预防策略

文章搜集了我国2000~2012年133起典型危险化学品环境污染事故,根据污染要素分为大气污染事故、水污染事故和土壤污染事故。运用数理统计方法,分析了各类事故的发生原因、危害、影响因素及应急处置特点。最后结合上述事故的分析,对我国危险化学品环境污染事故的应急管理工作提出几点建议。     

关于浮法玻璃工厂危险化学品的使用安全

浮法玻璃工厂在生产中使用的液氨、氢气、煤气、天然气、二氧化硫等都属于危险化学品。锡槽使用的保护气体氮氢气主要有氨分解制取,属于危险化学品的生产。氨、氢气、煤气、天然气、二氧化硫为国家重点监控的危险化学品,在生产和使用中存在着火灾爆炸、中毒窒息等危险。     

浅析苯乙烯储罐的安全设计

苯乙烯是一种极易自聚的物质,不加以控制会导致温度持续上升甚至引发储罐爆炸。苯乙烯为可疑致癌物,具刺激性。一旦发生事故,对环境具有严重的危害。本文根据苯乙烯的特性,从设备选型、工艺流程、安全检测等方面对苯乙烯储罐的安全设计进行分析和讨论。