基于魅力工学的盲盒玩偶外观要素研究

目的 随着潮玩市场的不断发展，盲盒玩偶受到了大量年轻消费者的青睐。通过研究盲盒玩偶外观与消费者偏好之间的关系，可以了解现代年轻群体的审美偏好，从而辅助设计师创造出更多满足消费者偏好的产品。方法 基于魅力工学等研究方法展开定性与定量研究。以POP MART盲盒玩偶为研究对象，首先进行深度访谈，根据访谈内容绘制盲盒玩偶外观评价构造图，得到消费者对偏好的盲盒玩偶外观的原始评价、抽象感受和关注的具体要素;再结合抽象语义设计Likert问卷，并进行问卷调研，以此获得盲盒玩偶的魅力评价均值;最后运用数量化I类理论进行多元回归分析，建立多个要素与消费者审美偏好之间的线性关系。结果 利用SPSS26.0统计软件进行定量研究，得到“治愈温馨”“纯洁可爱”“潮酷个性”“有趣搞怪”四类语义分别与消费者吸引力的线性关系，以及具有显著影响的外观设计要素。结论 研究获得了消费者对不同语义盲盒玩偶外观的审美偏好与关注要素，以及不同职业、不同年龄段消费者对盲盒玩偶外观审美偏好程度的差异。研究结果对潮玩设计师的创作具有参考性意义，也可将研究结果拓展应用于小型艺术装饰品/创意玩具等类似产品中。     

印刷电路板缺陷检测的实际应用

电路板在我们的日常生活中非常常见,这就使得印刷电路板的缺陷检测显得尤为重要。AOI作为新兴的检测PCB板缺陷的系统,在生产实际中正在被大家熟知并且应用。相较于传统的检测方式,AOI系统比较灵活,无论是在检测时间还是系统运算上,或者是对相关技术人员的要求相较于传统方式都比较有优势,本文就AOI系统在实际中的应用展开讨论,分析并且介绍了在实际应用中的具体细则。     

"不知火"柑橘全自动包装生产线的设计与研究

目的为了解决柑橘在实际包装过程中因于人工手动装袋、装箱等导致的效率低下问题,设计一条全自动柑橘包装生产线。方法基于“不知火”柑橘的特殊体型特征,使用传送带分级装置对其进行分级;通过倾斜皮带解决柑橘排列姿态的整理问题;经给袋式包装机装袋后,采用扭结式扎口装置对其进行封口;利用并联机器人对其进行装箱。通过计算生产节拍,合理规划每个工序的循环时间,并通过Flexsim软件对该生产线进行仿真分析与平衡优化。结果该生产线整体效率由89%提升到93%,能够正常运行且满足生产力的需求。结论该柑橘包装生产线实现了柑橘的分级、整料、装袋、装箱等工序,降低了工作强度,提高了生产效率,实现了包装过程的自动化。     

Resveratrol Affects Insulin Signaling in Type 2 Diabetic Goto-Kakizaki Rats

Resveratrol is a biologically active diphenolic compound exerting multiple beneficial effects in the organism, including anti-diabetic properties. This action is, however, not fully elucidated. In the present study, we examined effects of resveratrol on some parameters related to insulin signaling, and also on diabetes-associated dysregulation in Goto-Kakizaki (GK) rats with congenital type 2 diabetes. Resveratrol was given at the dose of 20 mg/kg b.w. for 10 weeks. It was shown that the expression and phosphorylation levels of insulin receptor in the skeletal muscle of GK rats were significantly decreased, compared with control animals. However, these changes were totally prevented by resveratrol. Liver expression of the insulin receptor was also reduced, but in this case, resveratrol was ineffective. Resveratrol was also demonstrated to significantly influence parameters of insulin binding (dissociation constant and binding capacity) in the skeletal muscle and liver. Moreover, it was shown that the expression levels of proteins related to intracellular glucose transport (GLUT4 and TUG) in adipose tissue of GK rats were significantly decreased. However, treatment with resveratrol completely abolished these changes. Resveratrol was found to induce normalization of TUG expression in the skeletal muscle. Blood levels of insulin and GIP were elevated, whereas proinsulin and GLP-1 diminished in GK rats. However, concentrations of these hormones were not affected by resveratrol. These results indicate that resveratrol partially ameliorates diabetes-associated dysregulation in GK rats. The most relevant finding covers the normalization of the insulin receptor expression in the skeletal muscle and also GLUT4 and TUG in adipose tissue.     

Evaluation of bismuth doped La2-xBixNiO4+δ (x = 0, 0.02 and 0.04) as cathode materials for solid oxide fuel cells

Bismuth doped La_2-xBi_xNiO_4+δ (x = 0, 0.02 and 0.04) oxides are investigated as SOFC cathodes. The effects of Bi doping on the phase structure, thermal expansion, electrical conduction behavior as well as electrochemical performance are studied. All the samples exist as a tetragonal Ruddlesden-Popper structure. Bi-doped LBNO-0.02 and LBNO-0.04 have good chemical and thermal compatibility with LSGM electrolyte. The average TEC over 20–900°С was 13.4 × 10^?6 and 14.2 × 10^?6 K^?1 for LBNO-0.02 and LBNO-0.04, respectively. The electrical conductivity was decreasing with the rise of Bi doping content. EIS measurement indicates Bi doping can decrease the ASR values. At 750 °C, the obtained ASR for LBNO-0.04 is 0.18 Ωcm², which is 56% lower than that of the sample without Bi doping, suggesting Bi doping is beneficial to the electrochemical catalytic activity of LBNO cathodes.     

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

Niemann–Pick type C (NPC) disease is a rare autosomal recessive inherited childhood neurodegenerative disease characterized by the accumulation of cholesterol and glycosphingolipids, involving the autophagy-lysosome system. Inhibition of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxy fatty acids (EpFAs) to 12-diols, exerts beneficial effects in modulating inflammation and autophagy, critical features of the NPC disease. This study aims to evaluate the effects of UB-EV-52, an sEH inhibitor (sEHi), in an NPC mouse model (Npc) by administering it for 4 weeks (5 mg/kg/day). Behavioral and cognitive tests (open-field test (OF)), elevated plus maze (EPM), novel object recognition test (NORT) and object location test (OLT) demonstrated that the treatment produced an improvement in short- and long-term memory as well as in spatial memory. Furthermore, UB-EV-52 treatment increased body weight and lifespan by 25% and reduced gene expression of the inflammatory markers (i.e., Il-1β and Mcp1) and enhanced oxidative stress (OS) markers (iNOS and Hmox1) in the treated Npc mice group. As for autophagic markers, surprisingly, we found significantly reduced levels of LC3B-II/LC3B-I ratio and significantly reduced brain protein levels of lysosomal-associated membrane protein-1 (LAMP-1) in treated Npc mice group compared to untreated ones in hippocampal tissue. Lipid profile analysis showed a significant reduction of lipid storage in the liver and some slight changes in homogenated brain tissue in the treated NPC mice compared to the untreated groups. Therefore, our results suggest that pharmacological inhibition of sEH ameliorates most of the characteristic features of NPC mice, demonstrating that sEH can be considered a potential therapeutic target for this disease.     

Dynamic Oscillation via Negative Differential Resistance in Type III Junction Organic/Two-Dimensional and Oxide/Two-Dimensional Transition Metal Dichalcogenide Diodes

Among many of 2D semiconductor-based devices, type III PN junction diodes are given special attentions due to their unique function, negative differential resistance (NDR). However, it has been found uneasy to achieve well-matched type III PN junctions from 2D–2D van der Waals heterojunctions. Here, the authors present other alternatives of type III heterojunctions, using 2D p-MoTe₂/organic n-type dipyrazino[2,3-f:2′,3′-h]quinoxaline-2,3,6,7,10,11-hexacarbonitrile (HAT-CN) and 2D p-WSe₂/n-MoO_x systems. Those junction diodes appear to well-demonstrate static and dynamic NDR behavior via resonant tunneling and electron–hole recombination. Extended to an inverter circuit, p-MoTe₂/n-HAT-CN diode enables multilevel inverter characteristics as monolithically integrated with p-MoTe₂ channel field effect transistor. The same NDR diode shows dynamic LC oscillation behavior under a constant DC voltage, connected to an external inductor. From p-WSe₂/n-MoO_x oxide diode, similar NDR behavior to those of p-MoTe₂/n-HAT-CN is again observed along with LC oscillations. The authors attribute these visible oscillation results to high peak-to-valley current ratios of their organic or oxide/2D heterojunction diodes.     

基于时间延迟的多类型维修与经济生产批量联合优化研究

针对目前未能较好的综合考虑多维修类型与经济生产批量联合优化的问题，首先考虑多类型维修关系，基于时间延迟理论求出故障和缺陷次数的表达式；其次，在此基础上，综合考虑生产费用和维修费用的基础上，构建了多类型维修和经济生产批量联合优化模型，以单位时间内总费用最小为优化目标，获得最优检查间隔期和经济生产批量；最后，通过算例分析验证了模型的有效性，说明了第一类缺陷检查次数的多少对费用和经济生产批量影响不大。     

松辽盆地齐家—古龙凹陷青山口组黑色页岩岩相类型与沉积环境

为研究松辽盆地齐家—古龙凹陷白垩系青山口组黑色页岩的沉积环境，利用岩心描述、薄片资料及地球化学数据开展岩相分析与沉积模式建立。结合有机碳含量和矿物组成划分出6种岩相，即富有机质黏土质页岩、富有机质长英质页岩、富有机质含生屑长英质页岩、贫有机质长英质泥岩、贫有机质含生屑长英质泥岩及贫有机质介壳灰岩。青山口组富有机质页岩并不全是静滞水体中悬浮沉积的产物，大量微米级的微波状纹层、透镜状层理、交错层理、粒序层理、冲刷充填构造以及定向排列的介屑佐证了浊流和底流作用的存在。微量元素分析表明，青一段湖盆面积大，水体深，虽有底流和浊流作用，但保持较强的还原环境，形成富有机质的黏土质页岩、粉砂质页岩和含生屑粉砂质页岩的互层，发育各种纹层。青二段、青三段随着湖平面下降，三角洲注入能力增强，贫氧环境受到破坏，有机质保存条件变差，岩相向贫有机质块状泥岩转变。