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1.
PurposeTo study the effect of daily disposable contact lens (DDCL) refitting in monthly contact lens (CL) wearers suffering from contact lens discomfort (CLD), and to assess if there is a placebo effect associated with this CLD intervention.MethodsSymptomatic CL wearers, according to the Contact Lens Dry Eye Questionnaire 8 (CLDEQ-8 ≥ 12 points), were divided into two groups. The study group was provided with DDCLs (delefilcon A) and the control group with a masked pair of their habitual monthly CLs (placebo effect) and were assessed after one month. Then, the control group was provided with the same DDCLs and evaluated one month later. The symptoms were recorded with the CLDEQ-8 and global rating of change scale (GRCS). Non-invasive tear break-up time (NITBUT), conjunctival hyperaemia, fluorescein staining, and lid wiper epitheliopathy (LWE) were evaluated. Changes between visits, groups, and the effect of each intervention were analysed.ResultsThirty-one participants (mean age: 23.2 ± 5.3 years) were recruited. The study group (n = 14) showed an improvement of -39.6 ± 25.8 % (p < 0.001) in CLDEQ-8 and 31.3 ± 14.6 points in GRCS (p < 0.001) after one month of DDCL use, while no changes in clinical tests were found. In the control group (n = 17), symptoms improved significantly after wearing the masked monthly CL (CLDEQ-8: -26.1 ± 31.0 %, p = 0.03; GRCS: 14.9 ± 17.0, p = 0.002), however a worsening in bulbar (26.5 ± 40.0 %; p = 0.02) and limbal hyperaemia (21.6 ± 34.7 %, p = 0.02) and an improvement of -19.1 ± 37.0 % (p = 0.049) in LWE was found. When the control group was fitted with the DDCL, improvements in GRCS (20.5 ± 25.5, p = 0.02), NITBUT (37.9 ± 42.3 %, p = 0.002), and conjunctival staining (-47.1 ± 59.9 %, p = 0.005) were noted.ConclusionsRefitting symptomatic monthly CL wearers with Delefilcon A DDCL is effective in reducing symptoms related to CLD. However, clinicians and researchers must be aware of the existence of a placebo effect when assessing the effectiveness of any CL refitting.  相似文献   
2.
沈从文的《中国古代服饰研究》实际上已意识到服饰史料的三个种类:实物、图像、文献,惜其未能详尽其言。本文从其中分析出最适合服饰史研究的三重证据法,并结合罗兰·巴特对于服饰符号体系的三分进行了进一步阐述,参照西方服装史的研究,提出运用三重证据法研究中国服饰史的重要意义。  相似文献   
3.
PurposeTo gain a better understanding of eye care professionals’ (ECPs) perceptions regarding the benefits of silicone hydrogel (SiH) daily disposable contact lenses (DDCL), particularly with respect to health, comfort and patient satisfaction.MethodsA survey was conducted with 300 ECPs in the United States, United Kingdom and Japan during November 2017. The survey comprised 34 statements relating to SiH DDCLs, to which the ECPs provided their level of agreement using a 6 point Likert scale. A minimum of 70% agreement was set to define majority agreement. Categories of statements included Health, Comfort, Patient Experience, and Standard of Care.ResultsECPs rated the highest levels of agreement to perceptions within the Patient Experiences and Health categories. The six statements receiving the highest ratings were “Silicone hydrogel 1 day lenses satisfy today’s patients’ demanding lifestyles” (93% agreement); “Silicone hydrogel 1 day lenses are the best choice to safeguard my patients’ eye health related to contact lens wear” (92%); “Silicone hydrogel 1 day lenses provide the best benefits to my patients” (92%); “Silicone hydrogel 1 day lenses provide better long term eye health for my patients than hydrogel 1 day lenses” (91%); “Silicone hydrogel is the healthiest lens material for my daily disposable patients” (90%); and “Silicone hydrogel 1 day lenses provide a better wearing experience for my patients than hydrogel 1 day lenses” (90%).ConclusionECPs perceive that SiH DDCLs offer long-term eye health and comfort for the patient and although the ECPs surveyed would not necessarily prescribe SiH DDCLs to all their patients, they would prescribe them to most of their patients. The results support the premise that while ECPs consider SiH 1 day contact lenses as the current “standard of care”; the principal barrier continues to be the perceived higher cost of these lenses.  相似文献   
4.
刘杰  李雅双  包瑛  刘春兰 《食品科学》2015,36(22):57-62
为了获得微波提取新疆阿魏根多糖的最佳工艺,以及新疆阿魏粗多糖的体外抗氧化活性,采用响应面法优化新疆阿魏水溶性多糖的微波提取工艺,在单因素试验的基础上选取液料比、提取温度、提取时间、微波功率进行试验设计,以所得多糖质量与苯酚硫酸法测得的多糖含量百分数的乘积作为优化指标,并检测新疆阿魏根多糖体外清除1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)自由基的活性。结果:最优工艺条件为液料比120∶1(m L/g)、提取时间13 min、提取温度80℃、微波功率600 W,多糖实际得率为6.93%,接近于理论值。新疆阿魏根多糖对DPPH自由基有很好的清除作用,当质量浓度为1 000μg/m L时,新疆阿魏根多糖对DPPH自由基的清除率为91.67%,作用接近于VC的清除作用。  相似文献   
5.
The concentrations of major and trace elements in Argentinean commercial powdered milk samples were determined with inductively coupled plasma mass spectrometry. Also the daily intake (DI) was calculated for adults and infants. The concentrations of B, Mg, Na, K and Ca were significantly higher in skimmed milk. Cu, Mo, Fe, Mn and Zn were significantly higher in infant formula. All the DIs were below the tolerable upper intake levels. The mean As concentration (26.0 ± 8.6 ng/g) in the powdered skimmed milk samples was slightly higher than in the others. Mean Pb concentrations ranged from 4.1 ± 2.1 to 13.5 ± 8.2 ng/g. The highest mean U concentration was 7.8 ± 2.6 ng/g for whole milk. This study contributes to the knowledge of major and trace elements in powdered milk and its contribution to the diet in Argentina.  相似文献   
6.
随着信息技术以及互联网的不断提升,信息化的办公软件也随之出现。办公软件的管理功能非常强大,那么,事业单位怎样对办公软件进行有效运用是一个值得人们所关注和研究的问题。本文主要对办公软件在事业单位日常管理中的作用做了探讨,并提出了新时期办公软件的发展方向与加强措施。  相似文献   
7.
The existing literature has documented that housing conditions, neighborhood characteristics, and socioeconomics are important determinants of residential satisfaction. However, the contribution of the actual usage of the residential environment to residential satisfaction has rarely been studied. To help fill in this gap, this study examines the contribution of the usage of housing and neighborhoods as well as the affective residential experience to residential satisfaction. We apply a subjective well-being framework and consider residential satisfaction and residential affective experience as two constituent components of the residential domain subjective well-being. Data were collected in Beijing from November 2011 to June 2012. The results show that home and neighborhood activities significantly affect residential satisfaction; higher levels of valence and activation of daily activities at home and in the neighborhood lead to more residential satisfaction.  相似文献   
8.
Purpose: sedentary lifestyles have resulted in an increasing number of people who are at increased risk of various conditions and diseases, including overweight, obesity, and metabolic syndromes. Our objective was to systematically record the daily life journal on a platform to increase the self-awareness and improve the sedentary lifestyle and to assist clinicians in understanding and facilitating patients’ daily physical activity.Method: we developed a portable activity pattern recognition system designed to automatically recognize the daily activity habits of users, and provide visualized life logs on the wellness self-management platform for patients and clinicians. Based on the participants’ and the clinician’s comments, appropriate modifications were made.Results: persuading people to improve their activities during non-working hours can enhance the general physical activity. Since users’ smartphones automatically monitor their energy expenditure, healthcare professionals can use these data to assist their patients in addressing health problems stemming from the obesity or metabolic syndromes, thus empowering users to avert or delay the progression of diabetes, cardiovascular disease and other complications.Discussion and conclusions: the clinical pilot study showed the feasibility of applying this persuasive technology to improve the physical activity of overweight people. The limitation of the study is the need for Wi-Fi and 3G environments and a smartphone.  相似文献   
9.
为了及时掌握小庄矿40309综放工作面瓦斯涌出量变化情况,杜绝该工作面回采过程中出现瓦斯隐患,现场连续采集了40309工作面回采过程中瓦斯涌出量数据,分析了绝对瓦斯涌出量和相对瓦斯涌出量随工作面回采的变化规律,研究了涌出量与日产量、日推进度和风排量的关系。研究结果表明:2019年5月25日至2019年8月14日,40309工作面绝对瓦斯涌出量随着工作面回采基本呈下降趋势,绝对瓦斯量维持在21.6~35.4m~3/min;40309工作面相对瓦斯涌出量维持在1.58~4.11m~3/t。工作面瓦斯涌出总量的平均值为26.91 m~3/min,其中,煤壁涌出5.65 m~3/min、落煤涌出2.02 m~3/min、采空区涌出2.83m~3/min,邻近层涌出16.41m~3/min,本煤层涌出量占工作面总涌出量的39.01%,邻近层涌出量占工作面总涌出量的60.99%。40309工作面绝对瓦斯涌出量随日产量增加而增加,随日推进度和风排量的增加呈增加趋势,但变化不太明显。40309工作面相对瓦斯涌出量随日产量增加呈指数衰减,随日推进度和风排量增加而增加。该研究有助于40309工作面瓦斯灾害事故防控,并为类似高瓦斯综放工作面回采设计提供指导。  相似文献   
10.
商业智能现在已广泛应用于各个领域,利用商业智能可以对趋势预测做出良好的支持,本文将其中一种常用商业智能的工具——数据仓库技术,应用于小区家庭的用水量预测研究。  相似文献   
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