给水管道腐蚀原因及防护措施探讨

给水管道在使用过程中很容易受到人为外力、管道材质、地下水、周围空气、土壤等因素的影响而腐蚀,影响了管道的使用质量和寿命,也带来较大的安全隐患。本文主要是从给水管道腐蚀原因出发,并探讨防护措施。     

Does interior color contrast enhance spatial memory?

This study investigated the effect of contrast in neutral-, warm-, and cool-colored spaces on spatial memory. Spatial memory was measured in terms of architectural scale and recollection of architectural elements and furniture. Participants (N = 114) viewed a short virtual simulation video of a residential studio and were asked to sketch a map of the architectural elements on distributed grid paper. Spatial memory was measured in terms of scale, and item recall rate. Contrast and hue had no significant effect on the memorization of proportional scale. However, high-contrast schemes allowed for a significantly higher recollection of architectural elements than low-contrast schemes. In comparing the effect of hues, a significant difference was seen in recalling detailed furniture and lighting items. Participants reported significantly better spatial memory of neutral and warm color schemes than of cool color schemes. There was no interaction effect between contrast and hue in the color combinations. These results can be applied in the design of color schemes for architectural spaces requiring enhanced spatial cognition and memory.     

QC小组活动原因分析要点

在开展问题解决型质量管理小组活动中,原因分析不可或缺。要分析到问题的末端原因,须展示问题的全貌,从人、机、料、法、环、测,从全面到重点,从综合到局部,分析到可以直接采取对策的因素为止。掌握原因分析的技巧和要点,有效采取头脑风暴法、5why分析法、5M1E分析环节,正确使用因果图、系统图、关联图,一定能够达到事半功倍的效果。     

舞台灯光对服饰视觉色感的影响研究

在舞台表演中,舞台灯光对人物服饰色彩的视觉体验有很大影响。文章基于光源、布料光谱信息和CIE-1931色度模型,模拟出计算面料色彩推测公式。并选取三种不同色调的LED光源作为舞台灯光,分别对七种面料进行色彩分析,发现深长春花蓝色、中蓝色面料在三种灯光下的色相变化不明显,与太阳光下呈现色彩接近;丁香紫色和兰花紫色面料与灯光色彩倾向一致;金黄色、橙红色和兰花紫色三种颜色在蓝光强烈情况下的色彩视认性更强。最后,结合舞台色彩的视认性和色彩的意象,为舞台服装设计与灯光设计在视觉色感的选择提供帮助。     

The Regulatory Functionality of Exosomes Derived from hUMSCs in 3D Culture for Alzheimer's Disease Therapy

Reducing amyloid‐β (Aβ) accumulation could be a potential therapeutic approach for Alzheimer's disease (AD). Particular functional biomolecules in exosomes vested by the microenvironment in which the original cells resided can be transferred to recipient cells to improve pathological conditions. However, there are few reports addressing whether exosomes derived from cells cultured on scaffolds with varying dimension can reduce Aβ deposition or ameliorate cognitive decline for AD therapy. Herein, both 3D graphene scaffold and 2D graphene film are used as the matrix for human umbilical cord mesenchymal stem cell culture, from which the supernatants are obtained to isolate exosomes. The levels of 195 kinds of miRNAs and proteins, including neprilysin, insulin‐degrading enzyme and heat shock protein 70, in 3D‐cultured exosomes (3D‐Exo) are dramatically different from those obtained from 2D culture. Hence, 3D‐Exo could up‐regulate the expression of α‐secretase and down‐regulate the β‐secretase to reduce Aβ production in both AD pathology cells and transgenic mice, through their special cargo. With rescuing Aβ pathology, 3D‐Exo exerts enhanced therapeutic effects on ameliorating the memory and cognitive deficits in AD mice. These findings provide a novel clinical application for scaffold materials and functional exosomes derived from stem cells.     

运输机皮带撕裂原因分析及特征实验研究

带式运输机是重要的连续性运输设备，皮带撕裂是造成带式运输机运输失效的重要因素。详细分析了引起皮带撕裂的常见原因，并给出了合理的预防措施。针对皮带撕裂现象构建皮带撕裂实验平台，并通过皮带受力应变实验分析掌握了皮带撕裂的特征，为预防皮带撕裂的发生提供了一定的理论依据。     

Animations showing Lego manipulative tasks: Three potential moderators of effectiveness

Evidence suggests that transient visual information, such as animations, may be more challenging to learn than static visualizations. However, when a procedural-manipulative task is involved, our evolved embodied cognition seems to reverse this transitory challenge. Hence, for object manipulative tasks, instructional animations may be more suitable than statics. We investigated this argument further by comparing animations with statics using a Lego task shown to university students, by examining three potential moderators of effectiveness: (a) the environment of manipulation (virtual or physical), (b) the quality of visual information (focused or unfocused), and (c) the presence of hands (no hands or with hands). In Experiment 1 we found an advantage of animation over statics, and no differences among the environments. In Experiment 2, we again observed an animation advantage, a small advantage of focused static information compared to unfocused static information, and a positive effect of not showing the hands.     

Root cause analysis of process fault conditions on an industrial concentrator circuit by use of causality maps and extreme learning machines

Model-based fault diagnosis tends to be too expensive or time-consuming to apply in the mineral processing industries, owing to the complexity and variability of operations. In contrast, data-based methods are inexpensive, but do not exploit the availability of first principle knowledge of plant operations. In this investigation, the use of process causality maps in conjunction with data-based fault diagnosis is considered as a hybrid methodology that can leverage the advantages of both approaches. Extreme learning machine algorithms are used to implement the data-based component of the approach. These algorithms can be deployed rapidly on large-scale systems and have the ability to deal with highly nonlinear systems. Two different variants are considered, viz. one used in combination with principal component analysis, as well as one with a bagging algorithm for fault diagnosis and applied to an industrial concentrator circuit in South Africa. The use of process causality maps led to significantly more effective fault diagnosis, while the use of extreme learning machines in combination with principal component analysis likewise allowed markedly better fault detection and diagnosis. In contrast, fault diagnosis with the bagging approach did not perform particularly well, owing to the high degree of correlation between the variables, which made it difficult to isolate individual causal variables.     

Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases

Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain’s utilization of ketones seems to depend mainly on the concentration in the blood, thus many dietary approaches such as ketogenic diets, ingestion of ketogenic medium-chain fatty acids or exogenous ketones, facilitate significant changes in the brain’s metabolism. Therefore, these approaches may ameliorate the energy crisis in neurodegenerative diseases, which are characterized by a deterioration of the brain’s glucose metabolism, providing a therapeutic advantage in these diseases. Most clinical studies examining the neuroprotective role of ketone bodies have been conducted in patients with Alzheimer’s disease, where brain imaging studies support the notion of enhancing brain energy metabolism with ketones. Likewise, a few studies show modest functional improvements in patients with Parkinson’s disease and cognitive benefits in patients with—or at risk of—Alzheimer’s disease after ketogenic interventions. Here, we summarize current knowledge on how ketogenic interventions support brain metabolism and discuss the therapeutic role of ketones in neurodegenerative disease, emphasizing clinical data.