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排序方式: 共有8719条查询结果,搜索用时 15 毫秒
1.
冠状病毒具有一层脂质膜。虽然复制需要劫持宿主的RNA工具来合成病毒体蛋白,但必须将其包裹在脂质膜中,促其萌生以扩展感染。最近研究表明,某些必需脂肪酸可以抑制其复制活性。脂质膜通常被认为是水溶物的脂肪屏障,但它对细胞和亚细胞的功能是高度有序和组分特异性的,其对病毒外壳可能也有最佳的特异性。虽然复制中DNA、RNA和蛋白质组成不受饮食影响,但脂质膜受其影响。此外,自1960年代以来,人们就知道男性对这些必需脂肪酸和膜完整性不足的敏感性高于女性。有证据表明,花生四烯酸和二十二碳六烯酸具有抗病毒、免疫、抗炎、控制血压和消退素活性,因此,迫切需要考察它们在Covid-19预防和治疗中的地位,也需重新评估现行的膳食指导。当前,有关脑、神经、血管和免疫系统等富含膜系统对脂质需求还尚未被详细认识。毫无疑问,这些脂质在几百万年来塑造人类基因组方面具有重要意义,因此,如果这些膜脂质失衡将会使人类面临机体紊乱和感染风险,且男性比女性风险更大。 相似文献
2.
为了解决城市廊道资源的紧张和公共交通发展需求的矛盾,出现了轨道交通和快速路的共建型式,即公轨共建的复合型交通模式,以温州市域铁路S2线一期工程的人民路站为例,研究公轨共建高架车站的结构设计要点。首先,为降低浅层气体对桩基的承载力及沉降影响,对遇到局部浅层气体发育的基础设计提供了合理的解决方案。然后针对公轨共建一体化车站分别进行了多遇和罕遇地震作用分析,研究表明构件及整体指标满足规范要求。最后针对工程的一些关键技术,如快速路桥面体系的选型、超长结构温度应力的控制措施、轨道梁挠度及应力的控制、快速路桥面振动对车站的影响等进行了分析,并给出了具体的解决方案和指导意见。 相似文献
3.
Jordana Cox 《Review of Communication》2019,19(2):127-146
ABSTRACTIn response to the latest “crisis” in the humanities, advocates have marched, rallied, fundraised, and—especially—argued. This essay contends that communication scholars can support the growing “case for the humanities” by analyzing argumentative strategies, and more specifically, by offering ethical argumentative strategies that avoid replicating structures of domination. In particular, we look to Mari Lee Mifsud's theorization of rhetoric as gift, which follows Henry W. Johnstone in conceptualizing argument as something other than winning over an adversary. We place Mifsud's theorization of the gift in conversation with the methods of the digital public humanities (DPH), which acknowledge and offer abundant resources for meaning-making. Through the methods of DPH, we offer a response to the humanities “crisis” that activates the humanities’ already broad constituencies by giving resources for humanistic inquiry rather than seeking to capture adversaries. Our case study is Photogrammar, a DPH project for organizing, searching, and visualizing the New Deal and World War II era photographs funded by the U.S. federal government. The project forefronts visual, nonlinear, and interactive argumentation in order to engage publics in generative humanistic inquiry. By enlisting participants and sharing expertise, Photogrammar shows how humanities advocates can deepen attachments to the humanities and build broad constituencies of collaborators and allies. 相似文献
4.
ABSTRACTThis paper explores intensified water crisis in Bangalore (or Bengaluru) in India by using the analytic of three hydrosocial regimes: the catchment-based regime, the hydraulic regime and the speculative urban regime. It uses a wide range of qualitative interviews, scientific reports and secondary sources to analyze shifting urban trajectories, agrarian relations and their interlinkages with water. Historical ruptures (in the realm of governance, urban growth and changing urban–rural dynamics) allow one to highlight the complex role of speculative logics that shape urban expansion and water scarcity. 相似文献
5.
无证书签名具有基于身份密码体制和传统公钥密码体制的优点,可解决复杂的公钥证书管理和密钥托管问题.Wu和Jing提出了一种强不可伪造的无证书签名方案,其安全性不依赖于理想的随机预言机.针对该方案的安全性,提出了两类伪造攻击.分析结果表明,该方案无法实现强不可伪造性,并在"malicious-but-passive"的密钥生成中心攻击下也是不安全的.为了提升该方案的安全性,设计了一个改进的无证书签名方案.在标准模型中证明了改进的方案对于适应性选择消息攻击是强不可伪造的,还能抵抗恶意的密钥生成中心攻击.此外,改进的方案具有较低的计算开销和较短的私钥长度,可应用于区块链、车联网、无线体域网等领域. 相似文献
6.
This study develops a crisis self‐efficacy index to provide a tool for crisis communication researchers and practitioners to understand behavioural aspects of crisis response better. Evaluations of public's crisis self‐efficacy using this index inform strategic message development to protect the public and minimize crisis damages by identifying the public/s most in need of self‐efficacy enhancing interventions. The index also provides practitioners a useful longitudinal index to evaluate progress in crisis preparedness programs and track changes in efficacy. A four‐stage survey index development process using structural equation modelling identifies four underlying constructs of crisis self‐efficacy: action, preventive, achievement and uncertainty management. 相似文献
7.
Susan Laxton 《History of Photography》2019,43(2):191-205
In its first instance as art practice among the historical avant-garde, photomontage was considered indispensable for its claim to intervene in perceptual processes, stimulating a critical mode of apprehension that would redirect the viewer away from conventions of aesthetic experience and towards a lived reception of art with pronounced relevance to the sociopolitical landscape. The effect was understood as structural, that is, activated not so much by direct political content, but by the stark and shocking effects of juxtaposition. By this measure, one challenge to contemporary photomontage is clear: in a postindustrial and postdigital visual landscape dominated by the structural fragmentation of the attention economy, the ‘simultaneity of the radically disparate’ (as Peter Bürger put it) might no longer present as heterodoxy but rather threaten to sink into invisibility. Yet with the migration off-screen of the effects of electronic media, a new urgency around moving photomontage structures into physical, public space is rising in contemporary practices. Shannon Ebner’s multi-part project A Hudson Yard (2014–15) is emblematic of the new ways in which artists are manipulating photomontage as a form of fully sensory experience that gives the medium room to play critically in both virtual and material space. By constructing subtle interruptions of naturalised commercial space, A Hudson Yard activates a détournement of instrumentalised language, using structures of juxtaposition to divert the discursive surfaces of public space away from consumption and towards what could be called a public poesis. 相似文献
8.
María Carrascal Pablo Sendra Antonio Alanís Plácido González Martínez Alfonso Guajardo-Fajardo 《Journal of Urbanism》2019,12(1):60-82
The creative city approach is going through a redefinition after the 2008 global financial crisis. In the specific case of South-European cities, in the context of austerity and cuts in public investment, creativity is becoming a strategy for achieving maximum social benefit and improvement of the built environment with minimum economic expenditure. This paper looks at this redefinition of creativity through the case study of Seville, in southern Spain. Through research methods that include video-recorded testimonies of the actors involved, mapping at the online platform “Laboratorio Q”, and public engagement activities, this paper explores how the civic society, professional, and public authorities have reinvented how to produce collective spaces. The paper concludes that bottom-up creative processes for producing collective spaces have become more visible since the 2008 crisis, when architects, planners, public authorities and policy-makers have been “learning” from them. 相似文献
9.
Few jurisdictions have translated internationally agreed social impact assessment (SIA) principles into statutory provisions. Governments and regulatory bodies tend to provide developers with high-level frameworks, or require that social impacts be ‘considered’, without specifying how this is to be done. In Australia, this lack of clarity leaves all parties uncertain about requirements for SIA. The New South Wales (NSW) Government’s 2017 release of the SIA guideline for State-significant mining, petroleum and extractive industry development represents an attempt to clarify requirements and provide guidance. In this paper, we describe the process of bringing this guideline to fruition from the perspective of being directly involved in its development, and highlight the challenges involved in integrating leading-practice principles into the state’s pre-existing policy framework. While the guideline represents a significant advance in policy-based SIA guidance, some aspects leave room for improvement. The real test of the guideline’s impact will lie in its influence on SIA practice in NSW, and ultimately in social outcomes for communities affected by resources projects. 相似文献
10.
仿生雾水收集材料:从基础研究到性能提升策略 总被引:1,自引:0,他引:1
由于水资源污染、淡水资源日益匮乏,水危机已经严重影响到人们的日常生活。从晨雾中捕获水气则可以缓解干旱地区的缺水问题。受纳米布沙漠甲虫、仙人掌、蜘蛛丝等动植物自发捕集雾水的启发,构建特殊润湿性的仿生雾水收集材料备受关注。详细总结了仿生雾水收集材料的最新研究进展,讨论了仿生集水材料的设计和制备方法,并从雾水收集的四大仿生策略出发,介绍了提升雾水收集效率的设计方案。在此基础上,分析了当前仿生雾水收集过程存在的问题,展望了此类材料未来的发展趋势和方向。 相似文献