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1.
冠状病毒具有一层脂质膜。虽然复制需要劫持宿主的RNA工具来合成病毒体蛋白,但必须将其包裹在脂质膜中,促其萌生以扩展感染。最近研究表明,某些必需脂肪酸可以抑制其复制活性。脂质膜通常被认为是水溶物的脂肪屏障,但它对细胞和亚细胞的功能是高度有序和组分特异性的,其对病毒外壳可能也有最佳的特异性。虽然复制中DNA、RNA和蛋白质组成不受饮食影响,但脂质膜受其影响。此外,自1960年代以来,人们就知道男性对这些必需脂肪酸和膜完整性不足的敏感性高于女性。有证据表明,花生四烯酸和二十二碳六烯酸具有抗病毒、免疫、抗炎、控制血压和消退素活性,因此,迫切需要考察它们在Covid-19预防和治疗中的地位,也需重新评估现行的膳食指导。当前,有关脑、神经、血管和免疫系统等富含膜系统对脂质需求还尚未被详细认识。毫无疑问,这些脂质在几百万年来塑造人类基因组方面具有重要意义,因此,如果这些膜脂质失衡将会使人类面临机体紊乱和感染风险,且男性比女性风险更大。  相似文献   
2.
In the present investigation, systematic grinding experiments were conducted in a laboratory ball mill to determine the breakage properties of low-grade PGE bearing chromite ore. The population balance modeling technique was used to study the breakage parameters such as primary breakage distribution (Bi, j) and the specific rates of breakage (Si). The breakage and selection function values were determined for six feed sizes. The results stated that the breakage follows the first-order grinding kinetics for all the feed sizes. It was observed that the coarser feed sizes exhibit higher selection function values than the finer feed size. Further, an artificial neural network was used to predict breakage characteristics of low-grade PGE bearing chromite ore. The predicted results obtained from the neural network modeling were close to the experimental results with a correlation of determination R2 = 0.99 for both product size and selection function.  相似文献   
3.
A new catalyst for both water reduction and oxidation, based on an infinite chain, {[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n, is formed by the reaction of NiCl2, 1,3-propanediamine (tn) and K3 [Fe(CN)6]. {[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n can electro-catalyze hydrogen evolution from a neutral aqueous buffer (pH 7.0) with a turnover frequency (TOF) of 1561 mol of hydrogen per mole of catalyst per hour (H2/mol catalyst/h) at an overpotential (OP) of 837 mV {[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n also can electro-catalyze O2 production from water with a TOF of ~45 mol O2 (mol cat)?1s?1 at an OP of 591 mV. Under blue light (λ = 469 nm), together with CdS nanorods (CdS NRs) as a photosensitizer, and ascorbic acid (H2A) as a sacrificial electron donor, {[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n can photo-catalyze hydrogen generation from an aqueous buffer (pH 4.0) with a turnover number (TON) of 11,450 mol H2 per mole of catalyst (mol of H2 (mol of cat)?1) during 10 h irradiation. The average of apparent quantum yield (AQY) is as high as 40.96% during 10 h irradiation. Studies indicate that {[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n exists in two forms: a cyano-bridged chain ({[Ni(tn)2]3 [Fe(CN)4 (μ-CN)2]2}n) in solid, and a salt ([Ni(tn)2]3 [Fe(CN)6]2) in aqueous media; Catalytic reaction occurs on the nickel center of [Ni(tn)2]2+, and the introduction of [Fe(CN)6]3- can improve the catalytic efficiency of [Ni(tn)2]2+ for H2 or O2 generation. We hope these findings can afford a new method for the design of catalysts for both water reduction and oxidation.  相似文献   
4.
吕尚文 《建筑结构》2022,52(1):24-29,35
为了解决城市廊道资源的紧张和公共交通发展需求的矛盾,出现了轨道交通和快速路的共建型式,即公轨共建的复合型交通模式,以温州市域铁路S2线一期工程的人民路站为例,研究公轨共建高架车站的结构设计要点。首先,为降低浅层气体对桩基的承载力及沉降影响,对遇到局部浅层气体发育的基础设计提供了合理的解决方案。然后针对公轨共建一体化车站分别进行了多遇和罕遇地震作用分析,研究表明构件及整体指标满足规范要求。最后针对工程的一些关键技术,如快速路桥面体系的选型、超长结构温度应力的控制措施、轨道梁挠度及应力的控制、快速路桥面振动对车站的影响等进行了分析,并给出了具体的解决方案和指导意见。  相似文献   
5.
信息化时代推动了我国科研水平飞速增长,为各行业、各领域提供先进的技术与设备支持,以此提升我国整体的GDP水平。文章认为在提升科研水平的过程中,科研项目管理系统起到举足轻重的作用,为科研活动的规范性、合理性与可行性提供了参考标准。  相似文献   
6.
Residential natural gas consumption depends on several factors. Available tools and methods to identify, categorize, and validate effective factors have some limitations, making consumption modeling more complex. Once a comprehensive model of effective consumption factors is developed for residential gas consumers, it can predict consumption. In addition, such a model could be used to verify the accuracy of measuring devices in order to reduce unaccounted for gas (UFG). The key factors affecting residential gas consumption were identified based on previous studies and their mutual effects were analyzed using a fuzzy cognitive mapping (FCM) method. The most significant factors and their effects on natural gas consumption in the residential sector were determined. In this study, for the first time, the expected consumption for each consumer was estimated using a consumption index. Generally, if the estimated consumption is significantly different from the amount recorded by the meter, it could suggest a potential source of UFG. The proposed method was applied to the data collected from the residential gas consumers of a small region in Iran (Dasht-e Arjan region, Fars province), and the results demonstrate the effectiveness of the proposed method.  相似文献   
7.
As global air pollution becomes increasingly severe,various types of fibrous filters have been devel-oped to improve air filter performance.However,fibrous filters have limitations such as high packing density that generally causes high-pressure drop and ultimately deterioration in the filtration effi-ciency.High-pressure particulate matter precipitators are limited in terms of scope for commercialization because they require high voltage supplies and ozone generators.In this study,we develop fibrous fil-ters with enhanced durability and improved performance using metallized microfibers decorated with metal-organic-framework(MOF)nanocrystals.Not only does the efficiency of the developed filters remain at or above 97%for 0.50-1.5 μm PMs but the durability also significantly increases.In addi-tion,using the water purification ability of the MOF,we explore the dye degradation effect of the hybrid microfibers by immersing them into Rhodamine B aqueous solution.In such an experiment the Rho-damine B aqueous solution is completely purified by the presence of the hybrid microfibers under the UV irradiation.  相似文献   
8.
贾承造 《石油学报》2021,41(12):1445-1464
石油和天然气是全球和中国最重要的一次能源。石油工业的生存发展是由油气资源、市场、技术和社会政治经济环境等要素决定的,其中,技术进步是最活跃和最关键的因素之一。中国已成为全球油气生产消费大国,中国石油工业上游的发展也高度依赖石油科技的进步。中国石油工业已形成了先进完整的理论技术研发和装备制造体系,支撑了油气产量持续稳产和增产。未来是中国社会经济发展的关键期,石油工业必将面对重大挑战与新的技术需求,大力实施国家创新战略,发展具有国际领先水平的新一代勘探开发理论技术,支撑油气产业发展,保障国家油气能源安全。中国石油工业上游在未来面临的重大挑战与技术需求包括:①满足中国未来现代化建设的巨大油气需求和保障油气供应安全,这当中必须加大中国油气勘探开发,同时进一步扩大全球及"一带一路"油气投资与生产;②实现中国石油长期稳产2×108t/a以上;③实现中国天然气产量上升至3 000×108m3/a并长期稳产;④发展海洋及深水油气勘探开发先进技术与装备;⑤形成新一代石油工程服务技术装备和数字化转型。中国石油工业上游未来的科技攻关方向和研发重点包括:①先进的石油大幅度提高采收率技术;②大气田勘探与复杂气田提高采收率技术;③非常规油气勘探开发技术;④海洋及深水油气勘探开发技术及装备;⑤"一带一路"油气勘探开发技术;⑥新一代石油工程服务技术装备和数字化转型。  相似文献   
9.
ABSTRACT

In response to the latest “crisis” in the humanities, advocates have marched, rallied, fundraised, and—especially—argued. This essay contends that communication scholars can support the growing “case for the humanities” by analyzing argumentative strategies, and more specifically, by offering ethical argumentative strategies that avoid replicating structures of domination. In particular, we look to Mari Lee Mifsud's theorization of rhetoric as gift, which follows Henry W. Johnstone in conceptualizing argument as something other than winning over an adversary. We place Mifsud's theorization of the gift in conversation with the methods of the digital public humanities (DPH), which acknowledge and offer abundant resources for meaning-making. Through the methods of DPH, we offer a response to the humanities “crisis” that activates the humanities’ already broad constituencies by giving resources for humanistic inquiry rather than seeking to capture adversaries. Our case study is Photogrammar, a DPH project for organizing, searching, and visualizing the New Deal and World War II era photographs funded by the U.S. federal government. The project forefronts visual, nonlinear, and interactive argumentation in order to engage publics in generative humanistic inquiry. By enlisting participants and sharing expertise, Photogrammar shows how humanities advocates can deepen attachments to the humanities and build broad constituencies of collaborators and allies.  相似文献   
10.
无证书签名具有基于身份密码体制和传统公钥密码体制的优点,可解决复杂的公钥证书管理和密钥托管问题.Wu和Jing提出了一种强不可伪造的无证书签名方案,其安全性不依赖于理想的随机预言机.针对该方案的安全性,提出了两类伪造攻击.分析结果表明,该方案无法实现强不可伪造性,并在"malicious-but-passive"的密钥生成中心攻击下也是不安全的.为了提升该方案的安全性,设计了一个改进的无证书签名方案.在标准模型中证明了改进的方案对于适应性选择消息攻击是强不可伪造的,还能抵抗恶意的密钥生成中心攻击.此外,改进的方案具有较低的计算开销和较短的私钥长度,可应用于区块链、车联网、无线体域网等领域.  相似文献   
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