基于章水泉竹艺非物质文化遗产的APP设计与研究

目的 针对章水泉竹艺非物质文化遗产在目前所遭遇的传承困境，利用数字媒体技术与互联网平台，打造推动其产品创新与文化传承的APP，助力其文化与产品的传播与推广，进而为湖北地区的非遗文化发展提供参考。方法 从章水泉竹器的本源出发，对其主要产品门类、工艺特点与艺术形式进行整理与分类，分析制约其传承与发展的主要原因，进而提出设计策略，并通过数字化传承、合作创新、成果推广3个策略模块针对性地进行APP设计。结论 章水泉竹艺APP设计通过利用数字媒体技术与互联网平台优势，将其历史与工艺资料进行数字化保存与展示，实现了文化保护功能；将其传统技艺与新锐设计思维通过线上平台进行融合与创新，实现了设计创新功能；将其制作流程与文化精髓通过直播与精准推送展现于公众视野，实现了产品推广功能。最终，为章水泉竹艺的传承与推广提供了新的路径。     

地域文化元素融入都江堰旅游产品的设计策略

目的 针对目前市面上都江堰旅游产品识别性较弱、同质化严重，对具有地域文化特色的旅游产品开发较少的问题，以地域文化元素作为都江堰旅游产品设计的核心，提出旅游产品的设计策略。方法 研究都江堰旅游产品设计，应从地域化和文化内涵入手。通过分析旅游产品现状，地域文化元素及新旅游时代背景下旅游产品的发展趋势，结合情感化设计理念，围绕用户体验进行探究，总结出都江堰旅游产品设计开发模式。以李冰石像和鱼嘴段水利工程元素为例，进行产品实践。结论 提出符合都江堰区域特色的旅游产品设计策略，即树立品牌意识、打造IP形象，以地域文化元素为设计核心，加强情感互动、与科技相融合的设计策略。赋予旅游产品更深层次的内涵，打造更多具有地域文化特色的旅游产品，从而推动历史文化与商业价值的融合，也能够为同类型旅游产品提供具有应用价值和参考的设计策略和思路。     

基于可供性的文化意象交互式智能音箱设计研究

目的 探索将文化民俗有效融入现代产品中的技术思路，保留并延续中华传统文化的生命力，有助于提升用户体验。方法 分析可供性与文化意象之间的主客观互通性;挖掘交互式智能音箱中的可供性触点;构建形态、感官、认知及情境四类可供性的设计框架;以楚文化意象为例进行设计实践，对智能音箱的产品造型与交互操作方式进行设计，并进行设计评价。结果 在可供性理论指导下的楚文化意象交互式智能音箱产品外观及交互体验设计较好地满足了设计目标和用户需求。结论 可供性有助于文化意象的正确提取与转化，可将意象抽象为具有实际意义的设计要素，帮助用户在生理与认知两个层面理解产品的使用方法，同时进一步回味、体验文化内涵和文化精髓。     

基于现代印刷工艺的非遗创意转化研究

目的研究现代印刷工艺在非遗创意转化中的应用。方法探讨非遗现代创意转化的依据与途径,根据联合国教科文组织对非遗的定义,明确创造性与现代性是非遗概念的核心特征。比较研究非遗现代创意转化较常见的两种形式:创意产品设计与创新印刷设计,突出创新印刷设计对开拓传统文化传承新形式的重要作用。通过对第68届美国印制大奖最高"班尼"金奖作品《山海经》线装图鉴、铜奖作品《团扇》明信片的具体案例分析,论述现代印刷工艺对非遗文化的全新呈现,成功引领中国非遗文化创意作品登上世界印刷的舞台。结论先进的印刷工艺与设计创意相结合,并依托印刷媒介传播的广泛性,能使非遗文化更好地融入新时代生活,确保非遗传承的生命力,从而实现非遗现代创意转化的真正意义。     

The influence of national culture on responsible innovation: A case of CO2 utilisation in Indonesia

Responsible innovation (RI) offers a promising step towards a more responsible adoption of innovations, such as new and emerging technologies. However, how RI would be practised in different cultural contexts and settings is still less studied, especially in the context of developing countries. Taking the utilisation of CO₂ in Indonesia as an empirical case, the purpose of this paper is to explore this issue through examining the influence of key characteristics of Indonesia's national culture on core dimensions of RI: anticipation, reflexivity, deliberation, responsiveness and participation. The different RI dimensions are applied in practice in a focus group discussion (FGD) and a round of interviews with different stakeholders that explored CO₂ utilisation in the country. Hofstede's classification of national cultural dimensions is used to single out key focus points for attention in these RI processes in the Indonesian context. The results from the experiment illustrate that culture matters in the application of RI dimensions in practice. In the sense that in order for RI to work well, the governance of core RI processes such as participation and deliberation has to be adjusted to social norms of what is considered legitimate, desirable and good behaviour. These norms differ across societies. The findings further suggest ways of applying RI dimensions in practice.     

猪源金黄色葡萄球菌vwb基因分布及对不同动物体外凝血致病作用的研究

为调查猪源金黄色葡萄球菌(Staphylococcus aurues,S. aureus)对不同动物宿主具有凝血致病作用及是否携带S. aureus凝固酶基因vwb~C、vwb~Sbo4、vwb~Sov2和vwb~Seq1,本文以厦门地区生猪养殖场、屠宰场和终端市场分离的130株S. aureus为研究对象,通过血浆凝固酶实验研究菌株对兔血浆、牛血浆和羊血浆的凝血致病性,采用PCR方法对实验菌株进行vwb~C、vwb~(Sbo4)、vwb~(Sov2)和vwb~(Seq1)基因的扩增。结果表明,兔血浆、牛血浆和羊血浆的阳性凝血率分别为100.00%、28.46%、28.46%。S.aureus凝固酶vwb~C,vwb~(Sbo4)和vwb~(Sov2)基因的检出率分别为100.00%(130/130),26.92%(35/130)和26.93%(38/130),vwb~(Seq1)基因未检出;来自生猪养殖场S.aureus中vwb~(Sbo4)和vwb~(Sov2)基因的检出率以及对牛血浆和羊血浆的阳性凝血率明显高于另外两种来源S. aureus,有显著性差异(p0.05)。研究结果说明猪源S. aureus对不同动物宿主具有凝血致病作用,为猪源S. aureus对不同动物宿主的凝血致病作用和适应性提供研究基础。     

食源性沙门氏菌分离株致病性研究和毒力相关基因检测

为研究零售鲜肉源沙门氏菌(Salmonella)优势血清型分离株的致病性及相关毒力基因的相关性,本研究分别取4种优势血清型S.derby、S.agona、S.enteritidis、S.typhimurium沙门氏菌分离株对SPF级昆明小鼠进行致病性实验,采用改良寇氏法计算半数致死量,判断4种血清型沙门氏菌的毒力,并通过聚合酶链式反应检测实验菌株中9种毒力相关基因的分布情况并分析其相关性。结果表明,4种不同血清型的沙门氏菌分离株对小鼠均有40%~70%的致死率,S.enteritidis、S.agona、S.derby对昆明小鼠的致病力相似,S.typhimurium较弱,且发现致病力的强弱与毒力岛SPI-2中的sse L基因密切相关。     

Genome-wide association studies (GWAS) and post-GWAS analyses for technological traits in Assaf and Churra dairy breeds

This study aimed to perform a GWAS to identify genomic regions associated with milk and cheese-making traits in Assaf and Churra dairy sheep breeds; second, it aimed to identify possible positional and functional candidate genes and their interactions through post-GWAS studies. For 2,020 dairy ewes from 2 breeds (1,039 Spanish Assaf and 981 Churra), milk samples were collected and analyzed to determine 6 milk production and composition traits and 6 traits related to milk coagulation properties and cheese yield. The genetic profiles of the ewes were obtained using a genotyping chip array that included 50,934 SNP markers. For both milk and cheese-making traits, separate single-breed GWAS were performed using GCTA software. The set of positional candidate genes identified via GWAS was subjected to guilt-by-association-based prioritization analysis with ToppGene software. Totals of 84 and 139 chromosome-wise significant associations for the 6 milk traits and the 6 cheese-making traits were identified in this study. No significant SNPs were found in common between the 2 studied breeds, possibly due to their genetic heterogeneity of the phenotypes under study. Additionally, 63 and 176 positional candidate genes were located in the genomic intervals defined as confidence regions in relation to the significant SNPs identified for the analyzed traits for Assaf and Churra breeds. After the functional prioritization analysis, 71 genes were identified as promising positional and functional candidate genes and proposed as targets of future research to identify putative causative variants in relation to the traits under examination. In addition, this multitrait study allowed us to identify variants that have a pleiotropic effect on both milk production and cheese-related traits. The incorporation of variants among the proposed functional and positional candidate genes into genomic selection strategies represent an interesting approach for achieving rapid genetic gains, specifically for those traits difficult to measure, such as cheese-making traits.