Impact sensitivities of energetic materials: Exploring the limitations of a model based only on structural formulas

Using a comprehensive set of drop weight impact test data (h₅₀) newly compiled from literature for 308 materials, a recent approach to predict impact sensitivities of nitro compounds is generalized to most explosive substances of interest. Compared to previous ones, this procedure is more thoroughly validated and exhibits a good predictive value. Furthermore, it yields new insight into the physical mechanisms involved, explaining for instance the unexpected desensitization of some oxygen-deficient triazoles upon nitration.     

An Analysis of Citation Counts of ETRI‐Invented US Patents

From its foundation until 2004, ETRI has registered over 1,000 US patents. This letter analyzes the characteristics of these patents and addresses the explanatory factors affecting their citation counts. For explanatory variables, research team related variables, invention specific variables, and geographical domain related variables are suggested. Zero‐altered count data models are used to test the impact of independent variables. A key finding is that technological cumulativeness, the scale of invention, outputs in the electronic field, and the degree of dependence on the US technology domain positively affect the citation counts of ETRI‐invented US patents. The magnitude of international presence appears to negatively affect the citation counts of ETRI‐invented US patents.     

低密度微泡沫压井液的研究与应用

吐哈油田部分区块地层压力系数小于0.9,常规水基压井液对储层伤害大,若使用油基压井液成本高,环境污染严重。通过实验优选出了一种低密度水基微泡沫压井液。该压井液具有密度低、泡沫强度高、稳定性好、携砂能力强等优点。现场应用表明,低密度微泡沫压井液稳定时间大于48 h,密度在0.70~0.99 g/cm3之间可调,抗油污染能力强,抗油大于8%,抗温在100℃以上,岩心污染后渗透率恢复值大于80%;并且施工方便,成本低,具有储层保护能力,使用微泡沫压井液的井表皮系数在0.20~2.34之间。     

回热损失对磁斯特林制冷循环制冷率的影响

从铁磁质的磁化强度一般表示式出发，探讨热阻和回热损失对磁斯特林制冷循环性能的影响，导出最大制冷率及其它性能参数。得到了结果适用于以顺磁质为工质的磁斯特林制冷循环。并指出在理想回热条件下的结论也适用于磁卡诺制冷循环。     

T8钢－聚有机硅氧烷仿生减粘降阻复合涂层的特性

研究了Ｔ８钢－聚有机硅氧烷仿生减粘降阻复合涂层的表面润湿性、磨料磨损特性及对土壤的减粘降阻性能与金属材料相比，仿生复合涂层的表面憎水性显著提高，水在其表面上的接触角达９２°；与４５钢相比，其磨料磨损的体积相对耐磨系数为６３％，降阻率达１５．２２％～２２．２７％     

浅谈无缝钢管的壁厚偏差

通过探讨、分析无缝钢管壁厚偏差产生的原因，提出了改善钢管壁厚偏差的一些措施，并结合实际生产，得出了比较满意的结果。     

Improving Wear Resistance of the Ni-base Thermal Spray-Welding Coating Using Rare Earths

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Intracellular localization of the antitumour drug adriamycin in living cultured cells: A confocal microscopy study

The intracellular distribution of the anthracyclinic antibiotic adriamycin in living cultured cells has been investigated by confocal microscopy. In human melanoma cells (M14), adriamycin was localized inside the nuclei. When adriamycin-treated M14 cells were allowed to recover in drug-free medium, a complete efflux of the drug from the nucleus was revealed. In recovered cells, a weakly fluorescent signal was observed in the perinuclear region. When M14 cells were recovered in a medium containing colcemid, a microtubule depolymerizing agent, the drug transport from the nucleus to the cell periphery appeared to be inhibited, suggesting that the microtubule network is strongly involved in drug transport mechanisms. In multidrug-resistant (MDR) cells the intracellular location of adriamycin was shown to be noticeably different from that of the parental wild-type cells. In particular, in resistant human breast carcinoma cells (MCF-7), adriamycin appeared to be exclusively located within the cytoplasm whereas the nuclei were shown to be completely negative. When adriamycin treatment was performed in association with MDR revertants, such as Lonidamine (inhibitor of the energy metabolism) or verapamil (inhibitor of the P-glycoprotein efflux pump), a marked enhancement of the cytoplasmic signal was observed in resistant cells. Under these conditions, adriamycin appeared concentrated in the perinuclear region, but the nuclei were still negative. Confocal microscopy proved to be a very useful method for the study of the intracellular transport of fluorescent substances, such as anthracyclinic antibiotics, and for the investigation of the multidrug resistance phenomenon in tumour cells.