面向智慧小镇建设的机房电气管线多目标优化布置方法

常规的管线布置优化方法难以在优化过程中得到全局搜索的最优解,导致安全性能无法得到保障,因此面向智慧小镇建设设计一个新的机房电气管线多目标优化布置方法。设置电气管线约束条件,将电压均值、单位时间内电流量、电气管线损耗恢复能力作为目标函数。优化管线布置全局搜索,使用交叉操作的方式不断得到更优解。建立多目标优化电气管线模型,得到电气管线多目标优化的数学模型。通过实验数据可知,该管线布置方法在算法测试中优于常规的3种算法,且在安全性能的检测中只与标准最优值相差6.22×10⁴,3个常规方法与标准最优值的差距为6.813×10⁴、7.6×10⁴、8.32×10⁴,因此可知该多目标优化的管线布置方法可以得到更优解。     

Dynamic Passivation in Perovskite Quantum Dots for Specific Ammonia Detection at Room Temperature

Perovskite structured CsPbX₃ (X = Cl, Br, or I) quantum dots (QDs) have attracted considerable interest in the past few years due to their excellent optoelectronic properties. Surface passivation is one of the main pathways to optimize the optoelectrical performance of perovskite QDs, in which the amino group plays an important role for the corresponding interaction between lead and halide. In this work, it is found that ammonia gas could dramatically increase photoluminescence of purified QDs and effectively passivate surface defects of perovskite QDs introduced during purification, which is a reversible process. This phenomenon makes perovskite QDs a kind of ideal candidate for detection of ammonia gas at room temperature. This QD film sensor displays specific recognition behavior toward ammonia gas due to its significant fluorescence enhancement, while depressed luminescence in case of other gases. The sensor, in turn‐on mode, shows a wide detection range from 25 to 350 ppm with a limit of detection as low as 8.85 ppm. Meanwhile, a fast response time of ≈10 s is achieved, and the recovery time is ≈30 s. The fully reversible, high sensitivity and selectivity characteristics make CsPbBr₃ QDs ideal active materials for room‐temperature ammonia sensing.     

It is in the box! Improving the usability and benefits of surgical safety checklists – A feasibility study

Up to 50% of preventable hospital medical errors occur in or after visiting an operating theater in the United States. To address this issue, hospitals use a Surgical Safety Checklist (SSC), which can reduce complications and mortality rates when used systematically. To execute it, surgeons read aloud from a poster hanging on a wall. However, studies report usability issues with posters and often surgeons execute the checklist from memory, which can reduce completion rates at the expense of patient safety. We present a novel approach to increase the SSC's usability in view of improving patient safety. Our DigitalChecklistBox displays the SSC directly on a patient's surgical drape and enables surgeons to navigate through the checklist using hand gestures. Evaluated with 10 surgeons, it increased the checklist elements' readability and navigation and brought additional functionalities to limit the number of missed elements.     

大新锰矿复杂空区群三维数值模型构建方法及胶结充填治理研究

矿山岩土工程数值分析中研究复杂空区群三维数值模型构建方法对空区治理具有现实意义。为精确分析矿山地下工程围岩移动和应力变化规律，特别是不同采矿方法形成的复杂空区的稳定性和矿柱应力变化，提出了3DMine-Surfer-Rhino-ANSYS-FLAC3D多软件联合建模方法，解决了复杂空区群三维数值模型构建和大数量小尺寸矿房矿柱网格剖分问题。以广西大新锰矿矿体开采为案例，构建了留矿法与房柱法形成的采空区的三维数值模型，模拟分析空区的稳定性和决策胶结充填治理方案。研究结果表明：（1）大新锰矿留矿法开采的空区部分顶柱有垮落风险；（2）房柱法开采的空区部分矿柱变形大，有塑性破坏；（3）对于胶结充填留矿法的空区，隔一充一充填方案治理效果更好，在治理初期地表沉降更小。     

重大活动保障中餐饮服务单位冷拼间自主开展快速检测技术的研究

目的 探讨在重大活动保障中餐饮服务单位冷拼间自主开展快速检测技术对及时筛选和排查冷拼间食品原料、操作工具和容器的可利用性。方法 针对2019年1月~2019年6月张家口市参与重大活动保障的部分餐饮服务单位冷拼间操作人员进行快检技术的培训和操作指导, 比较干预前后各单位在冷拼间的合格率。结果 2019年1~6月张家口市各类重大活动保障餐饮服务单位中冷拼间样品快速检测总合格率达到85.89%; 自主在冷拼间开展相关快速检测技术的餐饮服务接待单位合格率达到94.20%, 二者具有显著性差异(X2=65.09, P＜0.005)。结论 本研究充分证明了在重大活动保障中餐饮服务单位冷拼间自主开展快速检测技术的重要作用和意义。     

A two level metaheuristic for the operating room scheduling and assignment problem

Given a surgery department comprising several specialties that share a fixed number of operating rooms and post-surgery beds, we study the joint operating room (OR) planning and advanced scheduling problem. More specifically, we consider the problem of determining, over a one week planning horizon, the allocation of OR time blocks to specialties together with the subsets of patients to be scheduled within each time block. The aim of this paper is to extend and generalize existing approaches for the joint OR planning and scheduling problem. First, by allowing schedules that include patients requiring weekend stay beds which was not the case previously. Second, by tackling simultaneously both the OR planning and patient scheduling decision levels, instead of taking them into account in successive phases. To achieve this, we exploit the inherent hierarchy between the two decision levels, i.e., the fact that the assignment decisions of OR time blocks to surgical specialties directly affect those regarding the scheduling of patients, but not the reverse. The objective function used in this study is an extension of an existing one. It seeks to optimize both patient utility (by reducing waiting time costs) and hospital utility (by reducing production costs measured in terms of the number of weekend stay beds required by the surgery planning). 0–1 linear programming formulations exploiting the stated hierarchy are proposed and used to derive a formal proof that the problem is NP-hard. A two level metaheuristic is then developed for solving the problem and its effectiveness is demonstrated through extensive numerical experiments carried out on a large set of instances based on real data.     

常压室温等离子体诱变选育高产油脂皮状丝孢酵母的研究

研究了常压室温等离子体(ARTP)诱变时间对皮状丝孢酵母(Trichosporon cutaneum)致死率的影响,考察了不同质量浓度芝麻酚对皮状丝孢酵母生长的抑制程度,建立了一种快速高效选育高产油脂菌株的方法。结果表明:经过ARTP的40 s诱变后,接种到质量浓度为0. 15 mg/m L的芝麻酚培养基中28℃培养2 d,筛选出生长旺盛的菌株,然后接种到48孔液体培养基培养,并利用96孔板尼罗红荧光染色对培养菌株进行高通量筛选,选育出一株高产油脂菌株Trichosporon cutaneum A1。该菌株较原始菌株的生物量、油脂产量、油脂含量分别提高了41. 6%、123. 1%、57. 4%,且具有较好的遗传稳定性;通过气相色谱分析,其油脂脂肪酸组成与原始菌株相同,均为十六烷酸、硬脂酸、油酸、亚油酸。说明建立的芝麻酚抗性筛选和荧光标记高通量筛选相结合的ARTP选育方法是可行的,为其他产油脂菌株的筛选提供重要参考。     

高职院校计算机理实一体化实训室建设的探索

The integration of computer theory and practice in higher vocational colleges is the necessary condition to realize the train- ing of professional talents and improve the comprehensive quality of skilled talents. It is also the problem that needs to be solved first in the teaching of computer major in higher vocational colleges. This paper firstly introduces the definition and connotation of the integration of computer theory and practice, discusses on its construction objectives and basic concepts, then analyzes the con- struction value of the integration of computer theory and practice, including the contents of employment, professional teaching, cur- riculum supporting and qualification examination, finally discusses on the construction scheme of the training room of the integra- tion of computer theory and practice, and gives the objective evaluation of the construction results, hoping to effectively improve the level of the integration of computer theory and practice, and achieve the sustainable development of teaching.     

Anhydride‐Assisted Spontaneous Room Temperature Sintering of Printed Bioresorbable Electronics

Bioresorbable electronic devices are promising replacements for conventional build‐to‐last electronics in implantable biomedical systems and consumer electronics. However, bioresorbable devices are typically achieved by complex complementary metal oxide semiconductor fabrication processes that minimize exposure to humidity. Emerging printable techniques for bioresorbable electronics demand further improvement in electrical conductivity and mechanical robustness. This paper presents a room‐temperature spontaneous sintering method of bioresorbable inks that contain zinc nanoparticles and anhydride. The entire process can be conducted in atmosphere environment under 90% humidity within 300 min. It has minimum requirement for external heating and special ambient conditions, allowing humidity to trigger the surface chemistry of zinc nanoparticles and spontaneous welding between neighboring nanoparticles. The resulting bioresorbable patterns are highly conductive (σ = 72 400 S m^?1) and mechanically robust (>1500 bending cycles) to enable practical applications. A radio circuit achieved through the above method can operate stably over 14 days in air and disappear in water for less than 30 min. The spontaneous room‐temperature sintering represents a rapid and energy‐efficient approach to achieve high‐performance bioresorbable electronics with improved mechanical robustness and electrical performance, leading to broader impacts in the areas of healthcare, information security, and consumer electronics.     

常压室温等离子诱变与微生物微滴培养选育几丁质脱乙酰基酶高产菌株

该研究将室温等离子（ARTP）诱变与微生物微滴培养（MMC）技术应用于几丁质脱乙酰基酶（CDA）高产菌株的诱变选育，构建高产CDA菌株的诱变及高通量筛选方法。结果表明，经过4轮的ARTP诱变及MMC筛选，从200个不同的液滴中共筛选出5个发酵产酶明显提升的液滴，并通过进一步的平板筛选、24-深孔板复筛，获得了17株产酶提高300%以上的诱变菌株。通过对比分析17株高产菌株产CDA的能力，确定了1株最佳CDA高产菌株B4，其CDA最大产量比出发菌株提高了3.15倍，发酵产酶总量达到419.11 U/mL，为原始菌种的3.90倍。该研究为CDA高产菌株的诱变选育及高通量筛选提供了借鉴。