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M. R. Thompson 《Drug development and industrial pharmacy》2015,41(8):1223-1231
Twin screw granulation (TSG) is a new process of interest to the pharmaceutical community that can continuously wet granulate powders, doing so at lower liquid concentrations and with better product consistency than found by a high shear batch mixer. A considerable body of research has evolved over the short time since this process was introduced but generally with little comparison of results. A certain degree of confidence has been developed through these studies related to how process variables and many attributes of machinery configuration will affect granulation but some major challenges still lay ahead related to scalability, variations in the processing regimes related to degree of channel fill and the impact of wetting and granulation of complex powder formulations. This review examines the current literature for wet granulation processes studied in twin screw extrusion machinery, summarizing the influences of operational and system parameters affecting granule properties as well as strives to provide some practical observations to newly interested users of the technique. 相似文献
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In order to protect bolts from corrosion, electroplating such as zinc plating is widely used. However, hydrogen can easily penetrate or diffuse into the vacancies and dislocations between the lattices of bolt steel during electroplating. As the diffused hydrogen defects inside the lattice are in gaseous form, small cracks can easily be produced due to high pressure from the hydrogen gas. In this research, in order to determine the root cause of the fracture in pole fastening screws resulting from hydrogen embrittlement in typical electric motors, additional factors that accelerate hydrogen embrittlement fracture were selectively applied, including a small fillet in the head–shank transition and excessive hardness, and parametric study was performed experimentally. 相似文献
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针对烧结厂烧结电除尘灰的工况特性,介绍了输送烧结电除尘灰的正压气力输灰系统的特点、组成,还对在调试和试运行过程中遇到的故障进行了分析并制订了解决措施。 相似文献
5.
李彩虹 《南京工业职业技术学院学报》2008,8(2):1-3
根据PET薄膜的特点和高分子熔融态流动理论,分析了挤出回收用螺杆的各段结构,及螺杆参数选择,设计出大长径比、深槽、双排气、高效专用螺杆。 相似文献
6.
Industry widely uses rotary valves and blow tanks for the pneumatic conveying of products, each having their pros and cons depending on the specific application. This article shows the differing results obtained when low-velocity conveying a product through a common pipeline using both a drop-through rotary valve and a bottom-discharge blow tank feeder. A number of issues arise in the rotary valve system, the main one being rotary valve air leakage. A blow tank system, on the other hand, does not leak, as it is an enclosed system. The experimental results show dramatic differences in product throughput. Further exploration leads to a novel modification being made to the rotary valve system in an attempt to increase its capacity. The result of this modification shows a slight increase in output tonnage, but still significantly less than that obtained from the blow tank. 相似文献
7.
螺杆泵的检测方法及检测标准制定 总被引:2,自引:0,他引:2
螺杆泵检测是避免不合格螺杆泵下井、螺杆泵早期失效和提高螺杆泵使用寿命与采油效益的重要技术手段。重点介绍了模拟不同工况的螺杆泵工作特性检测系统及检测定子通径为10-60mm的定子衬套偏心度检测仪的组成及其检测方法和原理。针对大庆油田的实际情况,在进行大量室内和现场试验的基础上,制定了GLB120-27、GLB40-42和GLB500-14型螺杆泵的检测标准。检测技术及其标准实施以来见到了明显效果。 相似文献
8.
The standard deviation of differential pressure fluctuations between pressure taps in a 31.7 mm i.d. vertical downer was found to be proportional to the square root of the distance between the taps when measured under otherwise constant conditions. This finding confirms the prediction of a theoretical model based on the Central Limit Theorem of sampling statistics. Although the paper only presents experimental confirmation for downward flow, the theoretical model should be valid for flows in all orientations. Except at very low solids flows, the pressure gradient was found to be positive in the flow direction, indicating that rise in pressure due to static pressure more than compensated for frictional pressure losses. 相似文献
9.
地面驱动单螺杆泵杆柱的组合设计 总被引:21,自引:2,他引:19
根据地面驱动单螺杆泵的工作特点,分析了传递动力的抽油杯柱受力状况,认为抽油杆柱受复合载荷的作用,在承受扭矩的同时承受较大的轴向力,给出了各种载荷的计算方法。由第四强度理论,提出了把抽油杯柱设计成两级杆柱的等强度组合设计方法,即先按要求及标准确定两级杆柱的直径和长度,然后扶强度条件进行校核。根据油田的实际情况,编制了抽油杆柱电算程序,并给出了设计训一算实例。 相似文献
10.
随着设备高速化的日益发展,传统的螺杆设计方法及相应的供送特性评价体系已显落后。参照蜗型凸轮动力学性能的评价方法,建立了高速供送螺杆的动态性能评价体系,为高速化供送螺杆的设计提供了性能参照指标。 相似文献