A Temperature‐Responsive Boronate Core Cross‐Linked Star (CCS) Polymer for Fast and Highly Efficient Enrichment of Glycoproteins

Fast and highly efficient enrichment and separation of glycoproteins is essential in many biological applications, but the lack of materials with high capture capacity, fast, and efficient enrichment/separation makes it a challenge. Here, a temperature‐responsive core cross‐linked star (CCS) polymer with boronate affinity is reported for fast and efficient enriching and separating of glycoproteins from biological samples. The temperature‐responsive CCS polymers containing boronic acid in its polymeric arms and poly(N‐isopropyl acrylamide) in its cross‐linked core are prepared using reversible addition‐fragmentation chain transfer polymerization via an “arm‐first” methodology. The soluble boronate polymeric arms of the CCS polymers provide a homogeneous reaction system and facilitate interactions between boronic acid and glycoproteins, which leads to a fast binding/desorption speed and high capture capacity. Maximum binding capacity of the prepared CCS polymer for horseradish peroxidase is determined to be 210 mg g^?1, which can be achieved within 20 min. More interestingly, the temperature‐responsive CCS polymers exhibit rapid reversible thermal‐induced volume phase transition by increasing the temperature from 15 to 30 °C, resulting in a facile and convenient sample collection and recovery for the target glycoproteins. Finally, the temperature‐responsive CCS polymer is successfully applied to enrichment of low abundant glycoproteins.     

Fluorescent polyacrylate derivate from 4-biphenylmethanol with UV-green emission

In this paper we report the synthesis of a new polyacrylate named poly(1,1?-BP4MA) which is a derivate from 4-biphenylmethanol monomer. Poly(1,1?-BP4MA) was obtained by solution and bulk polymerization techniques to yield polymers with high molecular weight and high solubility. The study of the optical properties showed that poly(1,1?-BP4MA) is a fluorescent material with emission in the UV-green region and it has similar quantum yield to tryptophan.     

响应面法优化复方北冬虫夏草颗粒多糖提取工艺的研究

采用Box-Behnken设计星点响应面法对复方北冬虫夏草颗粒中多糖提取工艺进行优化研究。通过单因素试验考察料液比、提取时间和浸泡时间、提取次数4个因素对多糖得率的影响;通过Box-Behnken设计星点响应面试验,对北冬虫夏草、灵芝、甘草、大枣、小麦和桔梗中多糖提取工艺进行优化试验。优化后的提取工艺为:料液比1∶16.75(g/mL)、提取时间2 h、浸泡时间2.4 h、提取次数3次。通过Box-Behnken星点响应面试验方法进行的提取工艺优化,试验结果合理有效,优化效果良好。     

明星IP驱动的服装品牌产品创新模式研究

目的 针对当下服装品牌与明星IP合作常态化趋势下，明星IP服装同质化严重、服装品牌的投入与产出不断缩小等问题，服装品牌需要进行产品创新以更好地迎合市场提升品牌竞争力。方法 基于明星IP驱动的服装品牌产品创新视角，对产品创新模式分别从核心设计、产品语义设计与产品延伸设计三个方面提出假设，架构“行为—感知—购买意向”的研究模型，然后通过设计消费者调查问卷，对该假设进行实证检验。结果 产品核心设计通过产品感知与品牌感知，显著影响消费者对服装的购买意愿。产品语义设计变量对购买意愿的意向不显著，产品延伸设计对购买意向的影响为正。结论 说明了明星IP核心产品、明星IP语义产品、明星IP延伸产品促进了消费者对服装品牌的购买意愿。     

星轮装载机构技术参数的确定

根据星轮装载机构的工作运动特点及掘进机的工作性能,通过对星轮装载机构的力学分析,介绍了星轮装载机构的星轮结构、星轮转速及装载功率的确定方法,为研究设计提供理论依据,以供参考。     

星锥状药型罩形成射流侵彻混凝土的数值模拟

为了提高串联随进战斗部前级聚能装药结构对混凝土介质的破坏威力.文中利用LS-DYNA有限元分析软件对一种星锥状药型罩聚能装药结构形成射流侵彻混凝土靶板的过程进行数值模拟,分析了其成型过程以及对混凝土靶板的侵彻结果.通过与传统单锥状药型罩聚能装药结构形成射流侵彻混凝土靶板数值模拟结果的对比,表明由星锥状药型罩所形成的射流对混凝土靶板具有更强的破坏能力.为新型复合战斗部的前级聚能装药结构设计提供了依据.     

聚丙烯酸酯共混改性水性聚氨酯乳液性能研究

自制水性聚氨酯乳液,并采用共混方法制备聚丙烯酸酯改性水性聚氨酯乳液。研究了共混改性涂膜的结构和性能,结果表明,聚丙烯酸酯共混改性水性聚氨酯乳液的涂膜性能比水性聚氨酯乳液涂膜性能有明显的提高。经过机械共混改性后,PU/PA膜的耐热性有了较大的提高,拉伸强度比PU膜大,而膜变硬、断裂伸长率大大降低。     

Effect of milling time and pH on the dispersibility of lead zirconate titanate in aqueous media for inkjet printing

Micrometre-sized Pb(Zr_0.53Ti_0.47)O₃ (PZT) powder was dispersed in water, stabilized with the ammonium polyacrylate (PAANH₄) and milled to reduce the particle size. The influence of the pH, the amount of PAANH₄, and the milling time on the zeta potential, the PZT particle size and the particle size distribution was studied. The agglomeration took place regardless the milling time at pH 3. The suspension, containing 5 vol.% of PZT and 5 wt.% of PAANH₄, milled at pH 10 for 240 min, was stable and contained particles with a narrow, log-normal particle size distribution with the median size of 160 nm. The dissociated carboxyl groups from the PAANH₄ interacted with the PZT particles as evidenced by Fourier transform infrared spectroscopy and electrosterically stabilized the particles in water at pH 10. The PZT particle size and the stability of the suspension fitted the requirements for the ink, suitable for ink-jet printing.     

纳米二氧化钛/聚丙烯酸酯复合乳液的研究进展

对纳米二氧化钛/聚丙烯酸酯复合乳液的制备方法进行了综述,并对其存在的问题和未来的发展前景进行了展望。