低渗油田高压注水井在线酸化技术研究与试验

为实现对注水井的酸化解堵及增注降压的效果，保障低渗油田开发的高效性与安全性，对低渗油田高压注水井在线酸化技术进行研究和试验分析。制备复合酸液体系，确定在线酸化施工中的注酸速度与强度等参数，并设计在线监测装置实时监控在线酸化施工，检验结果表明，该复合酸液具有较高的螯合性与沉淀抑制性，具有较高的岩粉溶蚀率；应用该复合酸液实施在线酸化施工，施工后试验注水井的地层吸液性及注水量显著上升，井口油压及施工压力显著下降，增注降压效果明显，可解除注水井储层的堵塞物，为提升低渗油田开发的安全性与高效性提供保障。实验结果表明，所提技术使井口的油压由9.11MPa降到1.71MPa、泵注压力由9.77MPa降到7.51MPa，说明能有效缓解井口油压以及泵注压力，加大整体的施工排量，实现增注降压的目标。     

基于现代审美下的赣傩艺术元素分析与设计应用

目的 赣傩艺术元素内容丰富并保存完整,是研究我国古代赣傩地区文化与艺术的珍贵史料.研究赣傩艺术元素的提取及衍生图案的设计方法,在设计应用中表达赣傩傩面具、选取傩舞形和构筑傩庙魂,能给当代赣傩艺术元素的产品设计以指引.方法 通过直接引用、形意结合和局部强化的设计方法,增厚其丰富内涵、设计个性和主题意蕴.通过现代化审美中"绿色化、感性化、地域化"的要求,遵循"以退为进,化繁为简""多元并存,个性体现"的原则,强化赣傩艺术元素的独特风格.结论 用现代的手法,将特色的赣傩艺术元素植入到理性的产品设计中去,使赣傩艺术元素与现代设计思想有机结合.在继承传统文化与现代流行中找到契合点,深入挖掘赣傩艺术元素蕴含的文化精神、文化胸怀和文化自信,使中华传统文化在现代审美下进行创新再现.     

矿井电气自动化控制系统优化探究

随着煤矿产业的持续发展,矿井生产的自动化要求也不断提升,将PLC可编程技术应用到矿井电气自动化控制系统中,对于提升矿井综合效益意义重大。以此为着手点,以矿井提升机为对象,在分析PLC技术在提升机电气自动控制系统中应用的基础上,对电气设备单片机选型开展分析,同时总结了矿井提升机电气自动化控制系统的改造要求,希望能够为其他矿井相似工程的开展提供借鉴与参考。     

仓泵技术应用于电石粉尘回收装置的探讨

根据陕西金泰氯碱化工有限公司新建的电石粉尘回收装置的运行情况,探讨了仓泵技术的应用及仓泵在运行过程中的异常情况。指出装置运行后降低了电石消耗,每年可产生约400万元的经济效益,同时也降低了企业的安全风险,改善了乙炔生产现场环境。     

少量有机碳对单级自养脱氮工艺性能的影响

采用序批式生物膜反应器(SBBR),经过4个阶段的培养,快速富集好氧氨氧化细菌(AOB)和厌氧氨氧化细菌(AnAOB),并考察不同低碳氮比对工艺脱氮性能的影响。结果表明,NH4^+-N去除率可达到99%以上,TN去除率可达到90%以上。对应C/N=0、1和2时,反应器出水NH4^+-N和TN去除率分别为99.59%、99.5%、98.47%和93.75%、97.22%、98.11%。说明少量COD的存在,可实现同步硝化-厌氧氨氧化-反硝化,且在一定程度上提高脱氮效率。     

CD34⁺ CD38^- subpopulation without CD123 and CD44 is responsible for LSC and correlated with imbalance of immune cell subsets in AML

Acute myeloid leukemia (AML) is regarded as a stem cell disease. However, no one unique marker is expressed on leukemia stem cells (LSC) but not on leukemic blasts nor normal hematopoietic stem cells (HSC). CD34⁺ CD38- with or without CD123 or CD44 subpopulations are immunophenotypically defined as putative LSC fractions in AML. Nevertheless, markers that can be effectively and simply held responsible for the intrinsical heterogeneity of LSC is still unclear. In the present study, we examined the frequency of three different LSC subtypes (CD34⁺ CD38^-, CD34⁺ CD38^- CD123⁺ , CD34⁺ CD38^- CD44⁺ ) in AML at diagnosis. We then validated their prognostic significance on the relevance of spectral features for diagnostic stratification, immune status, induction therapy response, treatment effect maintenance, and long-term survival. In our findings, high proportions of the above three different LSC subtypes were all significantly characterized with low complete remission (CR) rate, high relapse/refractory rate, poor overall survival (OS), frequent FLT3-ITD mutation, the high level of regulatory T cells (Treg) and monocytic myeloid-derived suppressor cells (M-MDSC). However, there was no significant statistical difference in all kinds of other clinical performance among the three different LSC groups. It was demonstrated that CD34⁺ CD38^- subpopulation without CD123 and CD44 might be held responsible for LSC and correlated with an imbalance of immune cell subsets in AML.     

MSCs-exosomes in regeneration medicine: Current evidence and future perspectives

Exosomes, especially from mesenchymal stem cells, have attracted extensive attention in regeneration medicine. Mesenchymal stem cells derived exosomes (MSCs-exosomes) have shown anti-inflammatory, anti-oxidant, anti-apoptosis and tissue regeneration effects in a variety of tissue injury repair models. MSCs-exosomes hold many excellent properties such as low immunogenicity, biocompatibility, and targeting capability. With the in-depth study on the generation and function of exosomes, MSCs-exosomes are considered to be the bright stars in the field of regenerative medicine. However, there are still many obstacles to overcome in terms of exosomes isolation, clinical trials and safety evaluation. In this article, what we should focus on about MSCs-exosomes in regeneration medicine will be discussed.     

一株产低温脂肪酶酵母菌的鉴定及酶学性质

低温脂肪酶已成为工业低温工艺良好候选物，在生物质能源、食品、皮制品、废水处理等领域发挥重要作用。本文从实验室保藏的55株产低温脂肪酶酵母菌株中筛选出一株高产菌株NYNU 19160，通过形态学、生理生化以及ITS和26S rDNA序列分析，将该菌株鉴定为Papiliotrema fonsecae。经过硫酸铵分级沉淀、透析、浓缩将该脂肪酶纯化后，对酶学性质进行了研究。结果表明，该脂肪酶最适反应温度为20℃，最适作用pH为7.5，属于低温碱性脂肪酶；Cu²⁺显著促进该酶的水解活性，而Li⁺表现为显著抑制作用；有机溶剂乙腈、甲醇、乙酸对酶活性有较强的促进作用，而苯和正己烷则抑制了该酶的活性；该酶对对硝基苯酚丁酸脂（pNPC₄）底物表现出较强特异性。     

环保管家服务实例探索——以山西某热力公司为例

本文以山西某热力公司为例,介绍了环保管家定制化综合服务过程.企业通过引入环保管家,成功解决了企业发展的制约问题,全方位提升了企业实施环境管理,提高企业的竞争力.