基于SRAM的通用存算一体架构平台在物联网中的应用

最近,存算一体(IMC)架构引起了广泛关注,并被认为有望成为突破冯诺依曼瓶颈的新型计算机架构,特别是在数据密集型(data-intensive)计算中能够带来显著的性能和功耗优势.其中,基于SRAM的IMC架构方案也被大量研究与应用.该文在一款基于SRAM的通用存算一体架构平台——DM-IMCA的基础上,探索IMC架构在物联网领域中的应用价值.具体来说,该文选取了物联网中包括信息安全、二值神经网络和图像处理在内的多个轻量级数据密集型应用,对算法进行分析或拆分,并将关键算法映射到DM-IMCA中的SRAM中,以达到加速应用计算的目的.实验结果显示,与基于传统冯诺依曼架构的基准系统相比,利用DM-IMCA来实现物联网中的轻量级计算密集型应用,可获得高达24倍的计算加速比.     

草原石林：东北亚早白垩世花岗岩伸展穹隆和岩浆成矿爆发的地质遗迹及其形成过程

东北亚地区至少发育9个大型草原石林,属花岗岩石林的一种,是东北亚早白垩世巨量伸展和第四系冰川、风化作用的共同产物,主要特点是发育密集的近水平节理。本文通过整理岩浆岩专题填图和构造研究发现,这些石林的主体是早白垩世东北亚地区巨量伸展过程中形成众多的不对称花岗岩穹隆或同减薄岩体,岩体边部发育韧性剪切带,核部发布近水平岩浆流动面理,伸展和岩浆多期侵位导致与成矿密切相关的岩浆热液大量上涌,岩体抬升至地表,沿岩浆面理发育密集的近水平节理和部分垂直节理,后期沿这些构造面理发生的物理风化和化学作用(包括风蚀、冰川以及盐风化等)造就了千奇百怪的形态。草原石林是花岗岩地貌中的“另类”,不仅具有指示东北亚地区花岗岩形成时代(早白垩世)的特点,也是寻找晚中生代中国北方大规模成矿的良好标志体,而且风化形成的千姿百态的景色极具观赏价值,可以作为整个蒙古草原地区和大兴安岭南段地区特色的地学科普和生态旅游资源。     

柔性纤维结构超级电容器研究进展

为了提高电源器件与人体高曲率表面的适配性，电源器件突破平板结构的限制，衍生出了柔性纤维结构。柔性纤维超级电容器具有高功率密度、超长循环寿命和柔性舒适等特点有望成为最具前景的柔性可穿戴电源之一。因此，本文主要介绍了碳材料、过渡金属氧化物以及复合材料三种功能材料对柔性纤维超级电容器结构和性能的影响。每种材料凭借自身独特的性质在柔性纤维超级电容器器件中发挥着重要作用，并助力可穿戴电源器件的发展。     

谷氨酰胺代谢在原发性肝癌发生发展及治疗中的研究进展

肝癌是我国高发并且危害性极大的恶性肿瘤，其具有高死亡率并起病隐匿等特点。目前，肝癌治疗主要是以靶向药物，手术和放化疗为主，容易出现复发率高、耐药性强等现象。本文以谷氨酰胺代谢为切入点，对目前研究较多的肝癌相关的谷氨酰胺代谢酶及相关基因分别予以综述，以期为肝癌的发病机制及药物治疗提供开放性新思路。     

二次喷丸诱导应力及变形工程预测方法

为建立二次喷丸的等效分析方法,在单次喷丸诱导应力及饱和度已知的情况下,进行金属零件二次喷丸的诱导应力和变形的工程预测.以单次喷丸的饱和度曲线为分析基础,讨论了二次喷丸饱和度与喷丸时间的变化规律.用正弦函数的形式表达喷丸诱导应力,并建立了零件的平均诱导应力和饱和度之间的关系.结果表明:针对弹丸尺寸不同的二次喷丸过程,进行了基于多弹丸随机喷丸技术的有限元仿真,得到的喷丸诱导应力与理论结果相差5％左右;针对喷丸压力不同的二次喷丸过程,使用标准阿尔门试片进行了喷丸试验,试片变形与理论结果相差3％左右.仿真和试验结果均表明提出的预测方法有效、准确,可较好地预测二次喷丸后零件的残余应力和变形.     

认知双向中继网络在κ-μ衰落信道下的中断性能分析

针对认知双向中继网络在进行数据传输时面临的复杂无线信道场景问题,采用广义κ-μ分布构建认知双向中继网络中的视距和非视距无线传输信道,推导次网络在κ-μ衰落信道下的统一中断概率,并分析次网络在多种单一和混合衰落信道情况下的中断性能。仿真结果表明,无线信道的衰落程度对次网络的中断概率影响显著,依据衰落信道类型合理设置网络参数将有助于提升次网络中断性能。     

Non-Halogenated-Solvent Processed and Additive-Free Tandem Organic Solar Cell with Efficiency Reaching 16.67%

Organic solar cells (OSCs) have recently reached a remarkably high efficiency and become a promising technology for commercial application. However, OSCs with top efficiency are mostly processed by halogenated solvents and with additives that are not environmentally friendly, which hinders large-scale manufacture. In this study, high-performance tandem OSCs, based on polymer donors and two small-molecule acceptors with different bandgaps, are fabricated by solution processing with non-halogenated solvents without additive. Importantly, the two active layers developed from non-halogenated solvents show better phase segregation and charge transport properties, leading to superior performance than halogenated ones. As a result, a tandem OSC with high efficiency of up to 16.67% is obtained, showing unique advantages in future massive production.     

Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells

Tumor-specific enhanced delivery of chemotherapeutics and modulators to tumor cells and activated pancreatic stellate cells (aPSCs), respectively, represents safer and more effective therapy for pancreatic cancer. Herein, a membrane type 1-matrix metalloproteinase (MT1-MMP)-cleavable spacer is used to assemble low-density cRGDfK onto thermosensitive liposomes loaded with phosphorylated calcipotriol (PCAL) and doxorubicin (DOX), yielding MR-T-PD. The liposome-linked cRGDfK prodrug on MR-T-PD surface is first activated by MT1-MMP, which is selectively expressed on tumor endothelial cells, to release cRGDfK. The free cRGDfK specifically promotes tumor angiogenesis, leading to 3.4-fold higher accumulation and a wider distribution of MR-T-PD in tumors. Furthermore, MR-T-PD rapidly releases PCAL and DOX into the interstitium under heat treatment. The released DOX enters tumor cells to induce apoptosis, whereas the PCAL prodrug is converted to CAL by alkaline phosphatase on the surface of aPSCs; CAL can then enter aPSCs to induce quiescence and promote the antitumor effect of DOX. Finally, by enhancing the exposure of DOX and CAL to tumor cells and aPSCs, respectively, in a tumor-specific manner, MR-T-PD exerts superior efficacy (a 5.9-fold decrease in tumor weight) without causing additional side effects. Overall, this prodrug-based smart liposome system represents a promising paradigm for pancreatic cancer therapy.