Study on the performance of Cd2+ sorption using dimethylethylenediamine-modified zinc-based MOF (ZIF-8-mmen): optimization of the process by RSM technique

ABSTRACT

Cadmium as a highly toxic metal is released into the environment through paper production, metal processing, phosphate fertilizers, insecticides, and treatment of wastewater. Cadmium also inhibits the body activities and is very toxic for kidney and other organisms. In the current study, zinc-based metal–organic framework, zeolitic imidazolate framework (ZIF)-8, was synthesized and modified by dimethylethylenediamine (ZIF-8-mmen) for the removal of cadmium. To optimize the experiments, response surface methodology was applied with three variables including pH, adsorbent dosage, and contact time using central composite design. The optimum conditions for pH, dosage, and time were 2, 0.1 g, and 89 min, respectively, with removal efficiency of 85.38%. The Langmuir isotherm (q _m = 1000 mg/g) indicates the monolayer adsorption. The kinetic studies reveal that the Lagergren model was predominant and cadmium was not chemisorbed. Thermodynamic parameters show spontaneous, endothermic, and physisorption processes.     

Defect Engineering of MOF-Based Membrane for Gas Separation

Metal–organic frameworks (MOFs) are highly versatile materials that have been identified as promising candidates for membrane-based gas separation applications due to their uniformly narrow pore windows and virtually unlimited structural and chemical features. Defect engineering of MOFs has opened new opportunities for manipulating MOF structures, providing a simple yet efficient approach for enhancing membrane separation. However, the utilization of this strategy to tailor membrane microstructures and enhance separation performance is still in its infancy. Thus, this summary aims to provide a guideline for tailoring defective MOF-based membranes. Recent developments in defect engineering of MOF-based membranes will be discussed, including the synthesis strategies for defective MOFs, the effects of defects on the gas adsorption properties, gas transport mechanisms, and recently reported defective MOF-based membranes. Furthermore, the emerging challenges and future prospects will be outlined. Overall, defect engineering offers an exciting opportunity to improve the performance of MOF-based gas membranes. However, there is still a long way to go to fully understand the influence of defects on MOF properties and optimize the design of MOF-based membranes for specific gas separation applications. Nonetheless, continued research in this field holds great promise for the development of next-generation membrane-based gas separation technologies.     

(CoFe)Se2@NC超级电容器电极材料的制备及其电化学性能

金属-有机框架(MOF)衍生的过渡金属硒化物和多孔碳纳米复合材料具有巨大的储能优势,是应用于电化学储能的优良电极材料。采用共沉淀法制备CoFe类普鲁士蓝(CoFe-PBA)纳米立方,并通过静电组装在CoFe-PBA上包覆聚吡咯(PPy)得到CoFe-PBA@PPy;通过在400℃氮气中退火并硒化成功制备了氮掺杂的碳(NC)包覆(CoFe)Se₂的(CoFe)Se₂@NC纳米复合材料,并对其结构和形貌进行了表征。以(CoFe)Se₂@NC为电极制备了超级电容器,测试了其电化学性能,结果表明,在电流密度1 A/g时超级电容器的比电容达到1047.9 F/g,在电流密度5 A/g下1000次循环后具有良好的循环稳定性和96.55%的比电容保持率。由于其性能优越、无毒、成本低和易于制备,未来(CoFe)Se₂@NC纳米复合材料在超级电容器中具有非常大的应用潜力。     

GraftFast Surface Engineering to Improve MOF Nanoparticles Furtiveness

Controlling the outer surface of nanometric metal–organic frameworks (nanoMOFs) and further understanding the in vivo effect of the coated material are crucial for the convenient biomedical applications of MOFs. However, in most studies, the surface modification protocol is often associated with significant toxicity and/or lack of selectivity. As an alternative, how the highly selective and general grafting GraftFast method leads, through a green and simple process, to the successful attachment of multifunctional biopolymers (polyethylene glycol (PEG) and hyaluronic acid) on the external surface of nanoMOFs is reported. In particular, effectively PEGylated iron trimesate MIL‐100(Fe) nanoparticles (NPs) exhibit suitable grafting stability and superior chemical and colloidal stability in different biofluids, while conserving full porosity and allowing the adsorption of bioactive molecules (cosmetic and antitumor agents). Furthermore, the nature of the MOF–PEG interaction is deeply investigated using high‐resolution soft X‐ray spectroscopy. Finally, a cell penetration study using the radio‐labeled antitumor agent gemcitabine monophosphate (³H‐GMP)‐loaded MIL‐100(Fe)@PEG NPs shows reduced macrophage phagocytosis, confirming a significant in vitro PEG furtiveness.     

A type-centric framework for specifying heterogeneous, large-scale, component-oriented, architectures

Maintaining integrity and consistency, and effecting conformance in architectures of large-scale systems require specification and enforcement of many different forms of structural constraints. While type systems have proved effective for enforcing structural constraints in programs and data structures, most architectural modeling frameworks include only weak notions of typing or rely on first order logic constraint languages that have steep learning curves associated with them and that become unwieldy when scaling to large systems.We present the Cadena Architecture Language with Meta-modeling (CALM) — that uses multi-level type systems to specify and enforce a variety of architectural constraints relevant to the development of large-scale component-based systems. Cadena is a robust and extensible tool that has been used to specify a number of industrial strength component models and applied in multiple industrial research projects on model-driven development and software product lines.     

A representation method for performance specifications in UML domain

Performance related problems play a key role in the Software Development Process (SDP). In particular an early integration of performance specifications in the SDP has been recognized during last years as an effective approach to speed up the production of high quality and reliable software. In this context we defined and implemented a technique for automatically evaluating performance aspects of UML software architectures. To achieve this goal the starting UML model of the software architecture under exam has been mapped into a performance domain afterwards analyzed. The performance indices are inserted in the UML model exploiting the OMG Profile for Schedulability, Performance and Time Specification standard. However, to really automate the process, it was mandatory to specify the UML software representation by fixing semantic rules. The goal of this paper is the formalization of the model representation, characterizing the syntax and the semantics through which specifying performance requirements and behaviors into UML models in order to be compliant with the technique we implemented.     

基于CIM的嵌入式管理系统开发

为解决嵌入式环境下系统集成度的增加给管理和维护带来的困难,提出了基于通用信息模型的嵌入式管理系统方案。该模型提出创建通用模型的思想,它对各种设备的模型做出了规范,并对这些模型的管理操作进行标准化,因此,基于这种模型的管理系统和各种设备模型就具备了很好的扩展性和通用性。通过把通用信息模型的思想应用到嵌入式环境,对各个模块对象进行标准建模,以达到易于管理的目的。最后,实例应用结果表明了该方案的可行性。     

一个利用模型驱动体系结构技术的分布式系统实现

模型驱动体系结构(ModelDrivenArchitecture)的提出是OMG对于分布式互操作问题提供的一条新的解决途径。该文对MDA的产生背景、核心技术以及互操作模型框架作了深入剖析。以此为基础,在一个软件系统的开发中应用了MDA和核心技术收到了良好的效果。获得了应用MDA的实践经验。     

MIL-100(Fe) Sub-Micrometric Capsules as a Dual Drug Delivery System

Nanoparticles of metal–organic frameworks (MOF NPs) are crystalline hybrid micro- or mesoporous nanomaterials that show great promise in biomedicine due to their significant drug loading ability and controlled release. Herein, we develop porous capsules from aggregate of nanoparticles of the iron carboxylate MIL-100(Fe) through a low-temperature spray-drying route. This enables the concomitant one-pot encapsulation of high loading of an antitumor drug, methotrexate, within the pores of the MOF NPs, and the collagenase enzyme (COL), inside the inter-particular mesoporous cavities, upon the formation of the capsule, enhancing tumor treatment. This association provides better control of the release of the active moieties, MTX and collagenase, in simulated body fluid conditions in comparison with the bare MOF NPs. In addition, the loaded MIL-100 capsules present, against the A-375 cancer cell line, selective toxicity nine times higher than for the normal HaCaT cells, suggesting that MTX@COL@MIL-100 capsules may have potential application in the selective treatment of cancer cells. We highlight that an appropriate level of collagenase activity remained after encapsulation using the spray dryer equipment. Therefore, this work describes a novel application of MOF-based capsules as a dual drug delivery system for cancer treatment.