全文获取类型
收费全文 | 2135篇 |
免费 | 243篇 |
国内免费 | 210篇 |
专业分类
电工技术 | 193篇 |
综合类 | 232篇 |
化学工业 | 382篇 |
金属工艺 | 14篇 |
机械仪表 | 56篇 |
建筑科学 | 20篇 |
矿业工程 | 5篇 |
能源动力 | 19篇 |
轻工业 | 298篇 |
水利工程 | 15篇 |
石油天然气 | 9篇 |
武器工业 | 2篇 |
无线电 | 271篇 |
一般工业技术 | 180篇 |
冶金工业 | 29篇 |
原子能技术 | 12篇 |
自动化技术 | 851篇 |
出版年
2024年 | 7篇 |
2023年 | 44篇 |
2022年 | 162篇 |
2021年 | 175篇 |
2020年 | 55篇 |
2019年 | 53篇 |
2018年 | 46篇 |
2017年 | 70篇 |
2016年 | 65篇 |
2015年 | 77篇 |
2014年 | 88篇 |
2013年 | 126篇 |
2012年 | 148篇 |
2011年 | 142篇 |
2010年 | 116篇 |
2009年 | 115篇 |
2008年 | 131篇 |
2007年 | 146篇 |
2006年 | 119篇 |
2005年 | 114篇 |
2004年 | 93篇 |
2003年 | 70篇 |
2002年 | 74篇 |
2001年 | 46篇 |
2000年 | 42篇 |
1999年 | 44篇 |
1998年 | 22篇 |
1997年 | 25篇 |
1996年 | 28篇 |
1995年 | 26篇 |
1994年 | 25篇 |
1993年 | 15篇 |
1992年 | 16篇 |
1991年 | 13篇 |
1990年 | 13篇 |
1989年 | 4篇 |
1988年 | 6篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1984年 | 5篇 |
1982年 | 1篇 |
1980年 | 4篇 |
1979年 | 4篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1962年 | 1篇 |
1961年 | 2篇 |
1955年 | 1篇 |
排序方式: 共有2588条查询结果,搜索用时 15 毫秒
1.
正交曲线坐标下三维代数应力通量模型 总被引:7,自引:1,他引:6
针对弯曲及不规则明渠的水动力及物质输运特性,本文建立了曲线坐标系下的三维代数应力通量数学模型,对平面上弯曲及不规则复杂边界情形,采用Poisson方程进行正交曲线坐标变换,各向异性的湍流代数应力通量模型被引用于本文的模拟计算中,以体现复杂边界条件引起的水动力及物质输运特性的变化。通过180度强弯曲明渠水槽及贵溪电厂不规则边界河段物理模型试验两个实例计算表明,实测值与计算吻合良好,效果令人满意。 相似文献
2.
Lisa David Jianing Kang Daniel Dufresne Dan Zhu Sixue Chen 《International journal of molecular sciences》2021,22(1)
Systemic Acquired Resistance (SAR) improves immunity of plant systemic tissue after local exposure to a pathogen. Guard cells that form stomatal pores on leaf surfaces recognize bacterial pathogens via pattern recognition receptors, such as Flagellin Sensitive 2 (FLS2). However, how SAR affects stomatal immunity is not known. In this study, we aim to reveal molecular mechanisms underlying the guard cell response to SAR using multi-omics of proteins, metabolites and lipids. Arabidopsis plants previously exposed to pathogenic bacteria Pseudomonas syringae pv. tomato DC3000 (Pst) exhibit an altered stomatal response compared to control plants when they are later exposed to the bacteria. Reduced stomatal apertures of SAR primed plants lead to decreased number of bacteria in leaves. Multi-omics has revealed molecular components of SAR response specific to guard cells functions, including potential roles of reactive oxygen species (ROS) and fatty acid signaling. Our results show an increase in palmitic acid and its derivative in the primed guard cells. Palmitic acid may play a role as an activator of FLS2, which initiates stomatal immune response. Improved understanding of how SAR signals affect stomatal immunity can aid biotechnology and marker-based breeding of crops for enhanced disease resistance. 相似文献
3.
Veronique Demers-Mathieu Ciera DaPra Gabrielle Mathijssen David A. Sela Kirsi M. Jrvinen Antti Seppo Shawn Fels Elena Medo 《International journal of molecular sciences》2021,22(4)
Background: Preexisting immunity to SARS-CoV-2 could be related to cross-reactive antibodies to common human-coronaviruses (HCoVs). This study aimed to evaluate whether human milk antibodies against to S1 and S2 subunits SARS-CoV-2 are cross-reactive to S1 and S2 subunits HCoV-OC43 and HCoV-229E in mothers with a confirmed COVID-19 PCR test, in mothers with previous viral symptoms during COVID-19 pandemic, and in unexposed mothers; Methods: The levels of secretory IgA (SIgA)/IgA, secretory IgM (SIgM)/IgM, and IgG specific to S1 and S2 SARS-CoV-2, and reactive to S1 + S2 HCoV-OC43, and HCoV-229E were measured in milk from 7 mothers with a confirmed COVID-19 PCR test, 20 mothers with viral symptoms, and unexposed mothers (6 Ctl1-2018 and 16 Ctl2-2018) using ELISA; Results: The S2 SARS-CoV-2 IgG levels were higher in the COVID-19 PCR (p = 0.014) and viral symptom (p = 0.040) groups than in the Ctl1-2018 group. We detected a higher number of positive correlations between the antigens and secretory antibodies in the COVID-19 PCR group than in the viral symptom and Ctl-2018 groups. S1 + S2 HCoV-OC43-reactive IgG was higher in the COVID-19 group than in the control group (p = 0.002) but did not differ for the other antibodies; Conclusions: Mothers with a confirmed COVID-19 PCR and mothers with previous viral symptoms had preexisting human milk antibodies against S2 subunit SARS-CoV-2. Human milk IgG were more specific to S2 subunit SARS-CoV-2 than other antibodies, whereas SIgA and SIgM were polyreactive and cross-reactive to S1 or S2 subunit SARS-CoV-2. 相似文献
4.
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal disease with a 5-year survival rate of less than 10% following diagnosis. The aggressive and invasive properties of pancreatic cancer tumors coupled with poor diagnostic options contribute to the high mortality rate since most patients present with late-stage disease. Accordingly, PDAC is linked to the highest rate of cancer-associated venous thromboembolic disease of all solid tumor malignancies. However, in addition to promoting clot formation, recent studies suggest that the coagulation system in PDAC mediates a reciprocal relationship, whereby coagulation proteases and receptors promote PDAC tumor progression and dissemination. Here, upregulation of tissue factor (TF) by tumor cells can drive local generation of the central coagulation protease thrombin that promotes cell signaling activity through protease-activated receptors (PARs) expressed by both tumor cells and multiple stromal cell subsets. Moreover, the TF-thrombin-PAR1 signaling axis appears to be a major mechanism of cancer progression in general and PDAC in particular. Here, we summarize the current literature regarding the role of PAR1 in PDAC and review possibilities for pharmacologically targeting PAR1 as a PDAC therapeutic approach. 相似文献
5.
6.
在Matlab/Simulink仿真的平台上,利用跳频通信基本原理,在给定仿真条件下,建立了跳频通信系统模型,对系统进行了仿真,得到了宽带噪声干扰下的误码率信噪比曲线。通过跳频仿真图形前后对比,得出跳频通信系统的抗干扰能力优于传统的定频通信,在现代通信中有更高可靠性的结论。 相似文献
7.
基于神经网络原理、免疫系统和遗传算法的相关机理,构造了一个网络安全平衡器。该平衡器建立了抗原与抗体平衡态检测的数学模型、抗原与抗体的促进和抑制函数,提出了安全平衡态的概念,给出了抗原与抗体浓度的计算公式和模块化多层分类处理模型,利用促进、抑制函数和遗传算法适应度函数使已受攻击的网络再次达到一种新的安全平衡状态,这为网络安全提供了一个新的途径。理论证明网络安全方案是有效的。 相似文献
8.
讨论设计积分方程的数值解法在理论上需要研究两个问题.首先是逼近解的存在性(也就是数值解的存在性),其次是逼近解φn在一定意义下逼近φ,即可行性问题和收敛性问题.前者一般依赖后者的结果,而研究收敛性问题是一个相当困难的事. 相似文献
9.
黄清龙 《江苏石油化工学院学报》2010,(1):69-71
讨论同时求解代数方程所有单根时Halley迭代法的收敛性,给出了保证其收敛的初值应满足的一个充分条件,使Halley迭代法的收敛性获得新的表述和证明。 相似文献
10.
借助L-fuzzy映射和L-fuzzy集的像,给出了由L-fuzzy映射诱导的L-fuzzy闭包算子及其等价刻画.当L为有限分配格时,讨论了代数的L-fuzzy闭包算子及其所诱导的闭包系统的等价刻画. 相似文献