基于KANO模型的后共享时代单车设计决策研究——从设计师与消费者视角

目的 探究消费者对共享单车的需求偏好，获取用户和设计师对产品的认知差距，并提出相应的设计决策，为共享单车以及两轮车行业的产品创新提供启迪与参考。方法 从设计师思维与消费者偏好的视角出发，对共享单车消费者偏好的各项设计原则(属性)进行细致分类，建立8个评价维度与41个评价特征，采用KANO模型对有效回收样本进行定量统计及定性分析。结果 基于前期调研与KANO模型分析，提出后共享时代单车设计的相关策略。结论 在后共享单车时代下，设计师需要根据用户真实的产品偏好与体验感知进行设计策略的研究，以设计出真正满足用户需求和体验期望的产品。同时也证明KANO模型作为一种阐明用户不同感性需求的方法，有助于设计师进行设计决策的综合判断，提升设计的竞争力。     

Capsiate Intake with Exercise Training Additively Reduces Fat Deposition in Mice on a High-Fat Diet,but Not without Exercise Training

While exercise training (ET) is an efficient strategy to manage obesity, it is recommended with a dietary plan to maximize the antiobesity functions owing to a compensational increase in energy intake. Capsiate is a notable bioactive compound for managing obesity owing to its capacity to increase energy expenditure. We aimed to examine whether the antiobesity effects of ET can be further enhanced by capsiate intake (CI) and determine its effects on resting energy expenditure and metabolic molecules. Mice were randomly divided into four groups (n = 8 per group) and fed high-fat diet. Mild-intensity treadmill ET was conducted five times/week; capsiate (10 mg/kg) was orally administered daily. After 8 weeks, resting metabolic rate and metabolic molecules were analyzed. ET with CI additively reduced the abdominal fat rate by 18% and solely upregulated beta-3-adrenoceptors in adipose tissue (p = 0.013) but did not affect the metabolic molecules in skeletal muscles. Surprisingly, CI without ET significantly increased the abdominal fat rate (p = 0.001) and reduced energy expenditure by 9%. Therefore, capsiate could be a candidate compound for maximizing the antiobesity effects of ET by upregulating beta-3-adrenoceptors in adipose tissue, but CI without ET may not be beneficial in managing obesity.     

Dairy cow preference for different types of outdoor access

Dairy cows display a partial preference for being outside, but little is known about what aspects of the outdoor environment are important to cows. The primary aim of this study was to test the preference of lactating dairy cattle for pasture versus an outdoor sand pack during the night. A secondary aim was to determine whether feeding and perching behavior changed when cows were provided outdoor access. A third objective was to investigate how the lying behavior of cows changed when given access to different outdoor areas. Ninety-six lactating pregnant cows were assigned to 8 groups of 12 animals each. After a baseline phase of 2 d in which cows were kept inside the freestall barn, cows were habituated to the outdoor areas by providing them access to each of the 2 options for 24 h. Cows were then given access, in random order by group, to either the pasture (pasture phase) or the sand pack (sand phase). As we tested the 2 outdoor options using space allowances consistent with what would be practical on commercial dairy farms, the space provided on pasture was larger (21,000 m²) than that provided on the sand pack (144 m²). Cows were tested at night (for 2 nights in each condition), from 2000 h until morning milking at approximately 0800 h, as preference to be outdoors is strongest at this time. During the next 3 nights cows were given access to both outside options simultaneously (choice phase). Feeding and perching behaviors were recorded when cows were indoors during the day and night periods. Lying behavior was automatically recorded by HOBO data loggers (Onset, Bourne, MA). Cows spent more time outside in the pasture phase (90.0 ± 5.9%) compared with the sand phase (44.4 ± 6.3%). When provided simultaneous access to both options, cows spent more time on pasture than on the sand pack (90.5 ± 2.6% vs. 0.8 ± 0.5%, respectively). Time spent feeding indoors during the day did not change regardless of what type of outdoor access was provided, but there was a decline in perching during the day when cows were provided access to either outdoor option at night. Lying time in the pasture phase was lower than in the baseline or sand phase. During the nighttime, lying time outside was not different between the sand (55.4 ± 7.9%) and pasture (52.0 ± 7.4%) phases. In summary, cows spent a considerable amount of time outside during the night when given the opportunity and showed a preference for a large pasture versus a small sand pack as an outdoor area.     

Radon and moisture impacts from interventions integrated with housing energy retrofits

Energy retrofits can reduce air exchange, raising the concern of whether indoor radon and moisture levels could increase. This pre/post-intervention study explored whether simple radon interventions implemented in conjunction with energy retrofits can prevent increases in radon and moisture levels. Treatment homes (n = 98) were matched with control (no energy retrofits or radon intervention) homes (n = 12). Control homes were matched by geographic location and foundation type. t-tests were used to determine whether post-energy retrofit radon and moisture level changes in treatment homes significantly differed from those in control homes. The radon interventions succeeded in preventing statistically significant increases in first floor radon using arithmetic (p = 0.749) and geometric means (p = 0.120). In basements, arithmetic (p = 0.060) and geometric (p = 0.092) mean radon levels statistically significantly increased, consistent with previous studies which found that basement radon levels may increase even if first floor levels remain unchanged. Changes in infiltration were related to changes in radon (p = 0.057 in basements; p = 0.066 on first floors). Only 58% of the change in infiltration was due to air sealing, with the rest due to weather changes. There was no statistically significant association between air sealing itself and radon levels on the first floor (p = 0.664). Moisture levels also did not significantly increase.     

Large neighborhood search for the bike request scheduling problem

This paper introduces an efficient algorithm for the bike request scheduling problem (BRSP). The BRSP is built around the concept of request, defined as the pickup or dropoff of a number of identical items (bikes) at a specific station, within a certain time window, and with a certain priority. The aim of the BRSP is to sequence requests on (and hence determine the routes of) a set of vehicles, in such a way that the sum of the priorities of the executed requests is maximized, all time windows are respected, and the capacity of the vehicles is not exceeded. The generation of the set of requests is explicitly not a part of the problem definition of the BRSP. The primary application of the BRSP, from which it derives its name, is to determine the routes of a set of repositioning vehicles in a bike sharing system, although other applications exist. The algorithm introduced in this paper is based on a set of related greedy randomized adaptive search procedure followed by variable neighborhood descent (GRASP + VND) operators embedded in a large neighborhood search (LNS) framework. Since this paper presents the first heuristic for the BRSP, a computational comparison to existing approaches is not possible. We therefore compare the solutions found by our LNS heuristic to those found by an exact solver (Gurobi). These experiments confirm that the proposed algorithm scales to realistic dimensions and is able to find near‐optimal solutions in seconds.     

增材制造技术在超高膨胀封隔器中的应用

石油和天然气行业不断关注增材制造技术在航空航天和汽车行业的应用发展。研发了利用增材制造技术的超高膨胀封隔器,该封隔器的支承环系统由增材制造。增材制造设计大幅减少了支承系统的构件数量,同时显著提高了膨胀能力和额定压力。密封元件系统与增材制造支承环安装在一起,提供了极端膨胀比、零挤压间隙和对不规则孔的良好适应性。分析和测试结果表明:直径膨胀比高达111%,与常规封隔器相比,提高50%以上; 至少涵盖5种线重的套管(外径相同); 在148.89 ℃的温度下,密封元件能够保持压力68.95 MPa。介绍了增材制造技术、增材制造支承环概念、增材制造材料力学性能、密封元件系统优化和测试情况,以期给我国的完井作业提供借鉴。     

The role of Persian-language word exercise games in improving spelling of students with dyslexia: Word exercise games in improving spelling

Children with dyslexia have reduced sensitivity to phonological sounds and words, and this deficiency in lexical processing causes many problems for them. Word exercise games based on phonological awareness have emphasized the mistakes of students with dyslexia, attempting to help children avoid these mistakes. This study was conducted to investigate the effect of Persian-language word exercise games on the spelling of students with dyslexia. The design of the present study was quasi-experimental, with a pretest and posttest of an experimental group and a control group. Participants were 30 students with dyslexia from second grade to fifth grade in elementary schools in Bojnord, who completed the spelling test as a pretest and posttest. The experimental group played eleven 40-min sessions of word exercise games. The results showed that the word exercise programme improved the spelling of the children with dyslexia. This suggests that basing training on the phonological mistakes of students with dyslexia and using the word exercise games can improve their spelling.     

A general mechanistic model for predicting the fate and transport of phthalates in indoor environments

A mechanistic model that considers particle dynamics and their effects on surface emissions and sorptions was developed to predict the fate and transport of phthalates in indoor environments. A controlled case study was conducted in a test house to evaluate the model. The model‐predicted evolving concentrations of benzyl butyl phthalate in indoor air and settled dust and on interior surfaces are in good agreement with measurements. Sensitivity analysis was performed to quantify the effects of parameter uncertainties on model predictions. The model was then applied to a typical residential environment to investigate the fate of di‐2‐ethylhexyl phthalate (DEHP) and the factors that affect its transport. The predicted steady‐state DEHP concentrations were 0.14 μg/m³ in indoor air and ranged from 80 to 46 000 μg/g in settled dust on various surfaces, which are generally consistent with the measurements of previous studies in homes in different countries. An increase in the mass concentration of indoor particles may significantly enhance DEHP emission and its concentrations in air and on surfaces, whereas increasing ventilation has only a limited effect in reducing DEHP in indoor air. The influence of cleaning activities on reducing DEHP concentration in indoor air and on interior surfaces was quantified, and the results showed that DEHP exposure can be reduced by frequent and effective cleaning activities and the removal of existing sources, though it may take a relatively long period of time for the levels to drop significantly. Finally, the model was adjusted to identify the relative contributions of gaseous sorption and particulate‐bound deposition to the overall uptake of semi‐volatile organic compounds (SVOCs) by indoor surfaces as functions of time and the octanol‐air partition coefficient (K_oa) of the chemical. Overall, the model clarifies the mechanisms that govern the emission of phthalates and the subsequent interactions among air, suspended particles, settled dust, and interior surfaces. This model can be easily extended to incorporate additional indoor source materials/products, sorption surfaces, particle sources, and room spaces. It can also be modified to predict the fate and transport of other SVOCs, such as phthalate‐alternative plasticizers, flame retardants, and biocides, and serves to improve our understanding of human exposure to SVOCs in indoor environments.     

Aerobic Exercise Ameliorates Cancer Cachexia-Induced Muscle Wasting through Adiponectin Signaling

Cachexia is a multifactorial syndrome characterized by muscle loss that cannot be reversed by conventional nutritional support. To uncover the molecular basis underlying the onset of cancer cachectic muscle wasting and establish an effective intervention against muscle loss, we used a cancer cachectic mouse model and examined the effects of aerobic exercise. Aerobic exercise successfully suppressed muscle atrophy and activated adiponectin signaling. Next, a cellular model for cancer cachectic muscle atrophy using C2C12 myotubes was prepared by treating myotubes with a conditioned medium from a culture of colon-26 cancer cells. Treatment of the atrophic myotubes with recombinant adiponectin was protective against the thinning of cells through the increased production of p-mTOR and suppression of LC3-II. Altogether, these findings suggest that the activation of adiponectin signaling could be part of the molecular mechanisms by which aerobic exercise ameliorates cancer cachexia-induced muscle wasting.