Comparative Genomics Reveals 13 Different Isoforms of Mytimycins (A-M) in Mytilus galloprovincialis

Mytimycins are cysteine-rich antimicrobial peptides that show antifungal properties. These peptides are part of the immune network that constitutes the defense system of the Mediterranean mussel (Mytilus galloprovincialis). The immune system of mussels has been increasingly studied in the last decade due to its great efficiency, since these molluscs, particularly resistant to adverse conditions and pathogens, are present all over the world, being considered as an invasive species. The recent sequencing of the mussel genome has greatly simplified the genetic study of some of its immune genes. In the present work, we describe a total of 106 different mytimycin variants in 16 individual mussel genomes. The 13 highly supported mytimycin clusters (A–M) identified with phylogenetic inference were found to be subject to the presence/absence variation, a widespread phenomenon in mussels. We also identified a block of conserved residues evolving under purifying selection, which may indicate the “functional core” of the mature peptide, and a conserved set of 10 invariable plus 6 accessory cysteines which constitute a plastic disulfide array. Finally, we extended the taxonomic range of distribution of mytimycins among Mytilida, identifying novel sequences in M. coruscus, M. californianus, P. viridis, L. fortunei, M. philippinarum, M. modiolus, and P. purpuratus.     

气藏平均地层压力跟踪计算新方法

平均地层压力是产能评价和动态分析的基础，准确、快速获取平均地层压力对高效开发气藏意义重大。基于地层压力随时间变化的规律，分析了平均地层压力的变化规律。研究结果表明：平均地层压力等效点仅随时间发生改变，平均地层压力的下降速率等于或者近似等于井底流压的下降速率。从封闭弹性驱动气藏的物质平衡方程出发，考虑偏差系数和井底流压随平均地层压力的变化，推导建立了平均地层压力跟踪计算新方法，根据生产数据可迭代计算平均地层压力。方法验证结果显示，采气速度和采出程度共同影响模型的计算结果。应用实例表明，跟踪计算法与压力恢复试井和物质平衡法之间的相对误差均较小，满足工程计算精度要求，且跟踪计算法不需依托生产测试数据，节约了测试费用，避免了测试占产。     

基于双时间点检测的毫米波雷达人流量监测方法

针对现有基于视频监控的人流量统计方案成本高、算法复杂且不利于个人隐私保护的局限性，利用毫米波雷达体积小、成本低、分辨率高的特点，提出了一种基于双时间点检测的人流量监测方法。该方法先获取人体目标散射点位置和多普勒频移信息来构成点云数据，然后根据多普勒频移正负来判断人体的运动方向，并筛选具有高多普勒频移值的点云数据以降低干扰点对聚类结果的影响；在双时间点对特定区域内人员数量进行统计，并根据双时间点之间所获取的点云数据聚类结果对所统计人员数据进行修正。实验结果表明，该方法能够用匿名的方式以较高的正确率统计人员进出。     

基于纸浆纤维的贵重物品内包装塑造系统研究

为解决贵重物品与其内包装“契合度”不高的问题，提出基于纸浆纤维的贵重物品内包装塑造系统。系统通过三维扫描获取待包装物品的点云信息，经主控计算机进行数据处理，以下位机为执行中枢，辅之其他外部设备，利用纸浆纤维为贵重物品塑造“量身定制”的内包装，提升内包装契合度，增强保护效果，绿色环保，安全稳定。     

创新扩散视野下颈椎枕的产品设计策略研究

目的 针对现有产品设计在功能创新与产品采纳等方面的问题，基于创新扩散理论，以产品的功能、观念等方面及迭代策略方法为研究对象，创造和优化颈椎枕产品设计方法。方法 以智能助眠颈椎枕产品设计为实验样本，从创新扩散理论视角归纳产品创新过程中的核心问题，将产品的设计及优化方向纳入核心功能、用户体验、应用场景创新等不同优化路径，并在用户群体中划分出具有强扩散倾向的用户群体，根据其需求制定不同迭代策略，从而获得不同优化策略的细分迭代产品并投放市场进行扩散检验。结果 将2类不同产品线的迭代产品进行交叉对比验证，发现了总采纳比原产品提升了15.8%。同时对潜在用户群体进行针对性扩散实验结果，显示出显著的扩散潜量边界突破的表达。结论 探索了以创新扩散为目标的设计思路，在颈椎枕产品优化设计中的应用。提出了“扩散特征表达需求，并驱动创新，而后影响创新采纳效果”的产品设计模式。证明了根据扩散过程的信息反馈进行的产品迭代，提升了用户的新增采纳概率和模仿采纳概率。同时验证了以创新扩散需求为导向的产品设计策略研究的可行性。     

A robust model-free controller for a three-phase grid-connected photovoltaic system based on ultra-local model

In this paper, a robust model-free controller for a grid-connected photovoltaic (PV) system is designed. The system consists of a PV generator connected to a three-phase grid by a DC/AC converter. The control objectives of the overall system are to extract maximum power from the PV source, to control reactive power exchange and to improve the quality of the current injected into the grid. The model-free control technique is based on the use of an ultra-local model instead of the dynamic model of the overall system. The local model is continuously updated based on a numerical differentiator using only the input–output behavior of the controlled system. The model-free controller consists of a classical feedback controller and a compensator for the effects of internal parameter changes and external disturbances. Simulation results illustrate the efficiency of the controller for grid-connected PV systems.     

Design and validation of robotic bionic eye with multiple flexible ropes parallel mechanism inspired by oculomotor law

Producing a stable and agile bionic eye for visual image acquisition in robotics is a challenging task. In this paper, we design a bionic eye with mirror-symmetric distribution and cross-connection of flexible ropes. This mechanism is based on oculomotor law and the physiological structure of the extraocular muscles (EOMs). Specifically, the basic structural parameters are determined by Listing’s law, and the unique connection of the flexible ropes can realize the functions of the recti and oblique muscles. Furthermore, to mimic the trochlea structure, a pulley mechanism is constructed to permit the free movement of the flexible ropes. Through simulation and physical experiments, it is demonstrated that the bionic eye mechanism can move with agility under the structural parameters. The experimental results indicate that the proposed bionic eye mechanism has a superior motion accuracy of 2.798 mm, which is 6.7% of the maximum motion distance, and the repeatable accuracy of the mechanism can up to 0.210 mm.     

基于虚拟格网的建筑物点云轮廓线自动提取

在分析现有轮廓线提取方法不足的基础上，提出基于虚拟格网的建筑物轮廓线自动提取方法。该方法利用建筑物点云生成虚拟格网并进行二值填充；采用邻域分析方法进行边界格网的标记与追踪；为了避免边界追踪错误，设计了基于方向的单边缘格网抑制方法及基于距离的连接关系调整方法以改善提取结果质量；根据格网追踪结果，从原始建筑物点云中提取真实轮廓点以保持原始建筑物轮廓形态；采用随机抽样一致性估计及最小二乘拟合方法进行轮廓线规则化处理，实现建筑物轮廓线的自动提取。实验结果表明，该方法能快速从建筑物点云中提取轮廓线，可为建筑物轮廓线的自动提取提供一种可行的解决方案。     

基于多基表示的滑动窗口椭圆曲线多标量乘算法

标量乘运算从整体上决定了椭圆曲线密码体制的快速实现效率，在一些椭圆曲线公钥密码体制中需要计算多标量乘。多基数链的标量表示长度更短、非零比特数目更少，较好地适用于椭圆曲线标量乘的快速计算。为了提高椭圆曲线密码的效率，在已有的二进制域和素域的标量乘算法的基础上，结合滑动窗口技术、多基算法，提出新的更高效的多标量乘算法。实验结果表明，新算法与传统Shamir算法和交错NAF算法相比，其所需的运算量更少，能有效地提高椭圆曲线多标量乘算法的效率，使多标量乘的运算更高效。相比于其他算法，新算法的计算效率比已有的多标量乘算法提高了约7.9%~20.6%。     

放射性气载流出物取样代表性分析

为获取核设施放射性气载流出物单点连续监测取样位置,提出基于随机轨道模型(DRW)的气-固多相湍流耦合方法求解代表性取样区域。借助k-epsilon湍流模型模拟连续相,并引入离散颗粒模型(DPM)模拟离散相,建立基于DRW模型的排风管道内流道气-固多相湍流耦合计算模型,计算了核设施气载流出物在管道内流道流场分布规律,分析了内流道流体气旋角、气流速度、示踪气体浓度、气溶胶粒子浓度与管道高度间的关联关系。分析结果表明,随着截面高度的增加,气旋角、气流速度变异系数(COV)、示踪气体浓度COV及示踪气体浓度最大值与平均值的偏差逐渐降低并趋于稳定,气溶胶粒子浓度COV在截面6与截面8满足取样代表性要求;基于计算流体动力学方法可快速地确定出代表性取样位置,为气载流出物单点取样现场试验提供了理论参考依据。