Adaptive Discretization for Computerized Tomography

Two adaptive discretization frameworks are tested for computerized tomography (CT) data reconstruction. Removal of inactive pixels is primary motivation. Efficient and user independent entropy optimized masking is employed for spatial filtering purposes. Density of nodes at high gradient of reconstructed physical property is used as adaptation criterion. An alternative option, independent from noisy projection data and nature of the physical properties, is also discussed. Sensitivity analysis between the uniform and nonuniform (evolved via adaptive route) reconstruction grid reveals the utility of nonuniform grids. Iterative and transform based reconstruction techniques are used. Outcomes are tested successfully on three real world projection data from two different compact CT setups and one commercial high-resolution micro-CT scanner.     

融合环境因素的有限空间毒气扩散危害程度分析

为探究环境因素对毒气扩散危害程度的影响,通过对比有限空间内外环境差异,了解气体在有限空间内受力情况,并以传统高斯烟羽模型为基础,考虑扩散气体与有限空间边界碰撞产生的反射作用,建立了适用于有限空间气体扩散的改进高斯烟羽模型。深度剖析有限空间气体扩散环境,挖掘气体扩散主要关联因子,构建风速、地表粗糙度对有限空间气体扩散的影响函数;参照有限空间环境特征,分别设置3种不同风速与2种不同地表粗糙度,推求6种不同环境条件下气体扩散面积,阐明风速与地表粗糙度对有限空间气体扩散的影响程度。结果表明:在单一风速条件下,风速越高,地表粗糙度越低,洞室内H2S气体滞留时间越短,洞室内气体的扩散面积越小;风速越低,地表粗糙度越高,洞室内气体的扩散面积越大。     

Assessing students' conceptual understanding using an online three‐tier diagnostic test

When solving a mathematical problem, students who do not have sufficient conceptual understanding may perform poorly and exhibit misconceptions. This study was aimed to examine students' conceptual understanding and significant misconceptions when solving number sense‐related problems. An online three‐tier diagnostic test was administered to 125 fifth‐grade students with varied socio‐economic backgrounds in Hong Kong. Only 14.40% of the students exhibited high performance with high confidence, indicating that these students had a profound conceptual understanding of number sense. In addition, the majority of the students (66.40%) did not demonstrate number sense; these students exhibited several significant misconceptions and could solve the questions only by using a rule‐based method or guessing. Accordingly, most students performed unsatisfactorily on number sense‐related problems. This study is imperative in identifying early predictors and provides information for further compatible interventions in the teaching and learning of number sense in Hong Kong in particular and worldwide in general.     

Sense of place and mental wellness amongst African immigrants in Canada

This study examines the effects of self-perceived mental wellness and other socio-economic variables on sense of place amongst Ghanaian and Somali immigrants living in Hamilton, Ontario. Research results are based on the analysis of survey questionnaires (n = 236) of Ghanaian and Somali immigrant adults, with recent (0–5 years), mid-term (6–10 years), and long-term (more than 10 years) residency in Canada. Our findings revealed several significant factors of sense of place, including self-perceived mental wellness, income, age, employment, citizenship status, marital status, dwelling type, and length of residency in Canada. The findings highlight the need for research to incorporate sense of place into studies on visible minority immigrants and to focus on those factors contributing to place attachment amongst recent immigrants.     

Determining robust reaction kinetics from limited data

Accurate chemical kinetics are essential for reactor design and operation. However, despite recent advances in “big data” approaches, availability of kinetic data is often limited in industrial practice. Herein, we present a comparative proof-of-concept study for kinetic parameter estimation from limited data. Cross-validation (CV) is implemented to nonlinear least-squares (LS) fitting and evaluated against Markov chain Monte Carlo (MCMC) and genetic algorithm (GA) routines using synthetic data generated from a simple model reaction. As expected, conventional LS is fastest but least accurate in predicting true kinetics. MCMC and GA are effective for larger data sets but tend to overfit to noise for limited data. LS-CV strongly outperforms these methods at much reduced computational cost, especially for significant noise. Our findings suggest that implementation of CV with conventional regression provides an efficient approach to kinetic parameter estimation with high accuracy, robustness against noise, and only minimal increase in complexity.     

Combating Biofilm Associated Infection In Vivo: Integration of Quorum Sensing Inhibition and Photodynamic Treatment based on Multidrug Delivered Hollow Carbon Nitride Sphere

Recently, quorum sensing (QS) inhibitors (QSIs) have been combined with antibiotics to enhance antibiofilm efficacy in vitro and in vivo. However, targeting QS signals alone is not enough to prevent bacterial infections. Drug resistance and recurrence of biofilms makes it difficult to eradicate. Herein, photodynamic therapy (PDT) is selected to unite QSIs and antibiotics. A synergistically antibiofilm system, which combines QSIs, antibiotics, and PDT based on hollow carbon nitride spheres (HCNSs) is envisaged. First, HCNS provides the multidrug delivering ability, enabling QSIs and antibiotics to be released in sequence. Subsequently, multistage releases sensitize bacteria effectively, potentiating the chemotherapeutic effects of the antibiotics. Finally, the integration of QSIs and PDT not only minimizes the possibility of drug resistance, but also overcomes the problem of limited mass and extension of PDT. Even after 48 h of incubation, the bacterial biofilm is obviously inhibited. And its biofilm disperse efficiency exceeds 48% (compared with QSI‐potentiated chemotherapy group) and 40% (compared with PDT group). Besides, the inhibition of the QS system influences phenotypes related to virulence factor production and surface hydrophobicity, which weaken biofilm invasion and formation. Eventually, this system is applied to disperse bacterial biofilm in vivo. Overall, PDT and QS modulation are devoted to eradicate drug resistance and recurrence of the biofilm.     

结合深度学习与相关反馈的遥感图像检索

目的 针对基于内容的图像检索存在低层视觉特征与用户对图像理解的高层语义不一致、图像检索的精度较低以及传统的分类方法准确度低等问题，提出一种基于卷积神经网络和相关反馈支持向量机的遥感图像检索方法。方法 通过对比度受限直方图均衡化算法对遥感图像进行预处理，限制遥感图像噪声的放大，采用自学习能力良好的卷积神经网络对遥感图像进行多层神经网络的监督学习提取丰富的图像特征，并将支持向量机作为基分类器，根据测试样本数据到分类超平面的距离进行排序得到检索结果，最后采用相关反馈策略对检索结果进行重新调整。结果 在UC Merced Land-Use遥感图像数据集上进行图像检索实验，在mAP（mean average precision）精度指标上，当检索返回图像数为100时，本文方法比LSH（locality sensitive Hashing）方法提高了29.4%，比DSH（density sensitive Hashing）方法提高了37.2%，比EMR（efficient manifold ranking）方法提高了68.8%，比未添加反馈和训练集筛选的SVM（support vector machine）方法提高了3.5%，对于平均检索速度，本文方法比对比方法中mAP精度最高的方法提高了4倍，针对复杂的遥感图像数据，本文方法的检索效果较其他方法表现出色。结论 本文提出了一种以距离评价标准为核心的反馈策略，以提高检索精度，并采用多距离结合的Top-k排序方法合理筛选训练集，以提高检索速度，本文方法可以广泛应用于人脸识别和目标跟踪等领域，对提升检索性能具有重要意义。     

复杂膨胀性围岩条件下交岔点支护技术研究

针对复杂膨胀性围岩条件下交岔点高应力集中区围岩稳定性控制和支护技术难题，通过对交岔点围岩变形表现形式、交岔点围岩变形机理的研究分析，提出了交岔点支护难点及重点。基于围岩控制理论分析，提出了“有限让压的柔性支护+全断面封闭抗压的刚性支护技术”，前期柔性支护采用“高强、高预应力锚杆+锚索+喷浆”联合支护有限度控制围岩变形，允许围岩在可控范围内释放围岩应力|后期通过架设异形支架与支撑架组成的联合支护体并喷射混凝土对交岔点围岩进行全断面封闭抗压支护，有效控制巷道交岔点围岩的变形。确保了交岔点围岩变形的整体可控性、稳定性，达到了预期支护效果。     

受限空间安全作业管理浅析

受限空间因受作业场所限制,存在的危险因素较多,受限空间安全管理控制措施为:建立许可制,落实责任和措施,做好受限空间作业人员的个体防护,对受限空间作业的安全管理要实行从审批到应急处理全过程的控制。介绍了受限空间的危险特点和事故类型,提出了受限空间作业安全管理的具体措施。     

集团装药浅层水中爆炸数值模拟技术

探索了基于ANSYS／LS-DYNA进行集团装药浅层水中爆炸数值模拟的建模-求解-后处理过程，通过计算，对压力时程图、冲击波传播过程、水底变形形态进行了探讨，发展了水中爆炸问题研究的一种新手段。