Description of the thermodynamic properties and fluid-phase behavior of aqueous solutions of linear,branched, and cyclic amines

The SAFT-γ Mie group-contribution equation of state is used to represent the fluid-phase behavior of aqueous solutions of a variety of linear, branched, and cyclic amines. New group interactions are developed in order to model the mixtures of interest, including the like and unlike interactions between alkyl primary, secondary, and tertiary amine groups (NH₂, NH, N), cyclic secondary and tertiary amine groups (cNH, cN), and cyclic methine-amine groups (cCHNH, cCHN) with water (H₂O). The group-interaction parameters are estimated from appropriate experimental thermodynamic data for pure amines and selected mixtures. By taking advantage of the group-contribution nature of the method, one can describe the fluid-phase behavior of mixtures of molecules comprising those groups over broad ranges of temperature, pressure, and composition. A number of aqueous solutions of amines are studied including linear, branched aliphatic, and cyclic amines. Liquid–liquid equilibria (LLE) bounded by lower critical solution temperatures (LCSTs) have been reported experimentally and are reproduced here with the SAFT-γ Mie approach. The main feature of the approach is the ability not only to represent accurately the experimental data employed in the parameter estimation, but also to predict the vapor–liquid, liquid–liquid, and vapor–liquid–liquid equilibria, and LCSTs with the same set of parameters. Pure compound and binary phase diagrams of diverse types of amines and their aqueous solutions are assessed in order to demonstrate the main features of the thermodynamic and fluid-phase behavior.     

Impacts of slip and mass transpiration on Newtonian liquid flow over a porous stretching sheet

This article focuses on analytic solutions for Newtonian fluid flow with slip and mass transpiration on a porous stretching sheet using the differential transform method and Pade approximants of an exceptionally nonlinear differential equation. The impacts of different parameters including mass transpiration (suction/injection), Navier's slip, and Darcy number parameters on the velocity of the liquid and tangential stress are discussed. A comprehensive comparison of our results with the previous one in the literature is made, and the results showed good agreement. An investigation is conducted of a combination of magnetic liquids that are conceivably pertinent for wound medicines, skin repair, and astute coatings for natural gadgets. It is found that there is a decrease in the velocity profiles and the boundary layer thickness for the case of suction.     

高耸桥墩保护性爆破拆除关键技术

为解决高耸钢砼桥墩上部倾斜导致的工程质量不合格问题,采用保护性控制爆破将上部倾斜部分钢砼桥墩予以拆除,同时保留下部未偏斜部分桥墩不受破坏。采用开设组合形状切口,预开定向窗、导向窗;设置组合高差卸荷槽,预伤钢筋弱化抗压抗拉能力为关键措施的控制爆破方案。方案实施取得了十分满意的效果,上部拟拆除部分桥墩顺利倾倒下坠,下部保留部分桥墩完好无损。采用保护性控制爆破技术能高效、安全地解决类似高耸钢砼桥墩(构筑物)部分拆除、部分保留利用的问题,并能取得可观的经济、社会效益。     

Designing amorphous formulations of polyphenols with naringin by spray-drying for enhanced solubility and permeability

Naringin (NAR), a major flavanone (FVA) glycoside, is a component of food mainly obtained from grapefruit. We used NAR as a food additive to improve the solubility and permeability of hydrophobic polyphenols used as supplements in the food industry. The spray-dried particles (SDPs) of NAR alone show an amorphous state with a glass transition temperature (T_g) at 93.2 °C. SDPs of hydrophobic polyphenols, such as flavone (FVO), quercetin (QCT), naringenin (NRG), and resveratrol (RVT) were prepared by adding varying amounts of NAR. All SDPs of hydrophobic polyphenols with added NAR were in an amorphous state with a single T_g, but SDPs of hydrophobic polyphenols without added NAR showed diffraction peaks derived from each crystal. The SDPs with NAR could keep an amorphous state after storage at a high humidity condition for one month, except for SDPs of RVT/NAR. SDPs with NAR enhanced the solubility of hydrophobic polyphenols, especially NRG solubility, which was enhanced more than 9 times compared to NRG crystal. The enhanced solubility resulted in the increased membrane permeability of NRG. The antioxidant effect of the hydrophobic NRG was also enhanced by the synergetic effect of NAR. The findings demonstrated that NAR could be used as a food additive to enhance the solubility and membrane permeability of hydrophobic polyphenols.     

Electrochemical Quantification of Neurotransmitters in Single Live Cell Vesicles Shows Exocytosis is Predominantly Partial

Exocytosis plays an essential role in the communication between cells in the nervous system. Understanding the regulation of neurotransmitter release during exocytosis and the amount of neurotransmitter content that is stored in vesicles is of importance, as it provides fundamental insights to understand how the brain works and how neurons elicit a certain behavior. In this minireview, we summarize recent progress in amperometric measurements for monitoring exocytosis in single cells and electrochemical cytometry measurements of vesicular neurotransmitter content in individual vesicles. Important steps have increased our understanding of the different mechanisms of exocytosis. Increasing evidence is firmly establishing that partial release is the primary mechanism of release in multiple cell types.     

梁结构振动支承约束反力控制

支承或连接构件对梁结构的动力学性能有至关重要影响,必须保证其在振动过程中不发生破坏或者失效。通过合理设计和布局附加弹性支承可以实现对这些重要连接构件所承受约束反力的控制。应用微分变换法推导含附加支承的梁结构支承约束反力及其对于附加支承位置和刚度的灵敏度表达式,并通过优化设计附加支承位置和刚度实现具有弹性约束端的简支梁结构各支承约束反力的平衡,可提高结构的动力学性能。     

电容式力感知牙周探针设计建模与实验研究

针对当前牙周探针在探诊力控制方面的不足,提出一种基于悬臂梁挠曲效应的差动电容式力感知牙周探针解决方案,设计了探针验证结构,建立了探诊力作用下具有不规则形状的探针工作尖的挠曲模型,导出了探诊力和差动电容之间的求解方程,并通过仿真和实验对模型与方程进行了验证。结果表明,所建立的探针工作尖挠曲模型与静应力仿真结果的最大相对误差不超过±4.5%,所设计的力感知牙周探针多次重复探诊力检测实验的标准差小于均值的0.1%,所导出的求解方程的计算值与实验数据之间趋向一致,以探诊力为拟合权重进行修正后全量程的平均偏差为2.49%,具备进一步产品开发的可行性。