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1.
Obesity and hyperlipidemia are major risk factors for developing vascular diseases. Bee bread (BB) has been reported to exhibit some biological actions, including anti-obesity and anti-hyperlipidemic. This study aims to investigate whether bee bread can ameliorate vascular inflammation and impaired vasorelaxation activity through eNOS/NO/cGMP pathway in obese rats. Forty male Sprague-Dawley rats were randomly divided into four groups (n = 10/group), namely: control (normal group), obese rats (OB group), obese rats treated with bee bread (0.5 g/kg/day, OB/BB group) and obese rats treated with orlistat (10 mg/kg/day, OB/OR group). The latter three groups were given a high-fat diet (HFD) for 6 weeks to induced obesity before being administered with their respective treatments for another 6 weeks. After 12 weeks of the total experimental period, rats in the OB group demonstrated significantly higher Lee obesity index, lipid profile (total cholesterol, triglyceride, low-density lipoprotein), aortic proinflammatory markers (tumor necrosis factor-α, nuclear factor-κβ), aortic structural damage and impairment in vasorelaxation response to acetylcholine (ACh). Bee bread significantly ameliorated the obesity-induced vascular damage manifested by improvements in the lipid profile, aortic inflammatory markers, and the impaired vasorelaxation activity by significantly enhancing nitric oxide release, promoting endothelial nitric oxide synthase (eNOS) and cyclic guanosine monophosphate (cGMP) immunoexpression. These findings suggest that the administration of bee bread ameliorates the impaired vasorelaxation response to ACh by improving eNOS/NO/cGMP-signaling pathway in obese rats, suggesting its vascular therapeutic role.  相似文献   
2.
针对多目标绿色柔性作业车间调度问题(MGFJSP)的特点,提出从碳排放量、噪声和废弃物这3个指标来综合评定环境污染程度,建立了以最小化最大完成时间和环境污染程度为优化目标的MGFJSP模型,并提出了一种改进的人工蜂群算法来求解该模型。算法的具体改进包括:设计了一种三维向量的编码和对应解码方案,在跟随蜂搜索阶段引入一种有效的动态邻域搜索操作来提高算法的局部搜索能力,在侦查蜂阶段提出产生新食物源的策略用于增加种群的多样性。最后进行了实验研究与算法对比,以验证所建模型和所提算法的有效性。  相似文献   
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Artificial bee colony (ABC) algorithm has several characteristics that make it more attractive than other bio-inspired methods. Particularly, it is simple, it uses fewer control parameters and its convergence is independent of the initial conditions. In this paper, a novel artificial bee colony based maximum power point tracking algorithm (MPPT) is proposed. The developed algorithm, does not allow only overcoming the common drawback of the conventional MPPT methods, but it gives a simple and a robust MPPT scheme. A co-simulation methodology, combining Matlab/Simulink™ and Cadence/Pspice™, is used to verify the effectiveness of the proposed method and compare its performance, under dynamic weather conditions, with that of the Particle Swarm Optimization (PSO) based MPPT algorithm. Moreover, a laboratory setup has been realized and used to experimentally validate the proposed ABC-based MPPT algorithm. Simulation and experimental results have shown the satisfactory performance of the proposed approach.  相似文献   
5.
针对具有移动关节的7自由度机械臂逆运动学求解困难的问题,提出了一种基于改进人工蜂群算法的逆运动学求解方法。首先根据冗余机械臂的物理结构简化出几何模型,利用D-H法建立运动学模型,由坐标系变换得到正运动学的解。由于该冗余机械臂不满足Pieper准则,难以用传统方法求得封闭解;因此采用改进人工蜂群智能算法,利用位置误差与姿态误差的标准差作为目标函数,求取逆运动学的最优解,并利用Matlab编程进行仿真验证,仿真结果表明该方法准确有效,为具有移动关节的冗余机械臂逆运动学的求解提供了一种新的途径。  相似文献   
6.
针对核聚类中核参数选择依赖经验,最优聚类中心难以有效获取的问题,提出了一种仿电磁蜂群加权核聚类算法。首先,考虑不同特征对聚类结果的影响,对样本进行加权处理,利用核空间的Xie-Beni指标建立加权核聚类模型;然后,提出并引入仿电磁蜂群算法求解聚类模型,实现聚类中心、特征权重与核参数的同步寻优。利用该方法分别对3组标准测试样本集以及水电机组故障样本进行聚类测试,并与传统方法进行对比分析。试验结果表明,提出的仿电磁蜂群加权核聚类算法较传统聚类方法具有更高的精度,能够有效实现水电机组振动故障的准确聚类与识别,完成故障诊断。  相似文献   
7.
As a hot‐spot of 5G, the research on detection algorithms for massive multiple input multiple output (MIMO) system is significant but difficult. The traditional MIMO detection algorithms or their improvements are not appropriate for large scaled antennas. In this paper, we propose artificial bee colony (ABC) detection algorithm for massive MIMO system. As one advanced technology of swarm intelligence, ABC algorithm is most efficient for large scaled constrained numerical combinatorial optimization problem. Therefore, we employ it to search the optimum solution vector in the modulation alphabet with linear detection result as initial. Simulation and data analysis prove the correctness and efficiency. Versus the scale of massive MIMO systems from 64 × 64 to 1024 × 1024 with uncoded four‐quadrature‐amplitude‐modulation signals, the proposed ABC detection algorithm obtains bit error rate of 10 − 5 at low average received signal‐to‐noise‐ratio of 12 dB with rapid convergence rate, which approximates the optimum bit error rate performance of the maximum likelihood and achieves the theoretical optimum spectral efficiency with low required average received signal‐to‐noise‐ratio of 10 dB in similar increasing regularity, over finite time of low polynomial computational complexity of per symbol, where NT denotes the transmitting antennas' number. The proposed ABC detection algorithm is efficient for massive MIMO system. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
8.
Generation scheduling is an important concern of the current power system which is suffering from many obstacles of limited generation resources, grown energy demand and fuel price, inconsistent load demand and fluctuations of available wind power in case of the thermal–wind system. Smart grid system has a great potential of tumbling existing power system difficulties with intelligent infrastructure and computation technologies. Three different distributed energy resources, namely, distributed generation, demand response and gridable vehicles are used in this paper to overcome the power system hitches. The classical generation scheduling is solved with insertion of the cost of demand response and the cost model pertaining to underestimation and overestimation of fluctuating wind power. The modified optimization problem is solved using an efficient Global best artificial bee colony algorithm for 10 generating units test system. Generation scheduling in the smart grid environment yields a significant reduction in the total cost.  相似文献   
9.
利用混沌的特点设计了一种混沌局部搜索算子,将该算子加入到原始人工蜂群算法中提出了一种混沌蜂群算法(CABC),并用之来优化焊接条的结构设计问题。该问题的目标是在满足约束条件下使得制造焊接条所需的总费用最小,是一个典型多维多约束非线性规划问题。为了不让人工蜂群算法优化该问题时陷入局部最优解,在原始蜂群算法末期的最优值附近进行混沌局部搜索,使其跳出局部最优,有效提高了算法的局部寻优能力。最后对焊接条设计问题进行了仿真计算,并将结果与其他文献中的结果进行了对比,显示了混沌人工蜂群算法优化焊接条设计问题的优越性。  相似文献   
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